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The map label for this gene is emrR [H]

Identifier: 22124831

GI number: 22124831

Start: 1040620

End: 1041156

Strand: Reverse

Name: emrR [H]

Synonym: y0923

Alternate gene names: 22124831

Gene position: 1041156-1040620 (Counterclockwise)

Preceding gene: 22124832

Following gene: 22124830

Centisome position: 22.63

GC content: 45.62

Gene sequence:

>537_bases
TTGAAATTAATGAGGCGCCTCATAATGGAAAGTTCATTCTCCCCCATAGAACAGATGCTGAACTCTCGAGCAAAACGTCA
GAAGGATTTCCCCTACCAGGAAATTCTACTCACCCGCTTGAGTATGCATATGCACAGTAAATTGCTAGAAAATCGCAATA
AAATGCTGAAAGCGCAAGGAATTAACGAAACCTTGTTTATGGCATTAATTACGCTAGACGCCCAAGAGAGTCGCAGTATC
CAACCATCAGAATTGAGTGCCGCGTTGGGTTCTTCGCGCACGAATGCGACGCGTATCGCTGATGAATTAGAGAAGAAAGG
CTGGATTGAGCGTCGGGAAAGCCATAATGACCGCCGTTGCCTACATTTGCATCTCACCGAGGCTGGGATTGAGTTTTTAC
ATCAACTTCTCCCGCCACAACATAAATGCCTGCATTTTCTTTGGTCGACCCTGACGGAGCAAGAGCAGCAACAGCTTGAA
ATGCTGACCCGTAAGTTGTTAACCCGTTTAGATCAGATGGAAATATCGGAACAGTAA

Upstream 100 bases:

>100_bases
AATGCCAATGGCCGATTCACCTTGGCTGAATAACACTAATTGCTAAATTTTTCTCGTAATATACCGTTTACATTATTAGT
AACTATCGTTACTGTACCAT

Downstream 100 bases:

>100_bases
TTCCACTATTTCTATCCAGAGAACAAACCATGTCATTCCAACATAACGGGGAATGGGCGCCTTTTGGTGCCATTTGTTTA
TGAATGGGCGGTAATAAAAA

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKLMRRLIMESSFSPIEQMLNSRAKRQKDFPYQEILLTRLSMHMHSKLLENRNKMLKAQGINETLFMALITLDAQESRSI
QPSELSAALGSSRTNATRIADELEKKGWIERRESHNDRRCLHLHLTEAGIEFLHQLLPPQHKCLHFLWSTLTEQEQQQLE
MLTRKLLTRLDQMEISEQ

Sequences:

>Translated_178_residues
MKLMRRLIMESSFSPIEQMLNSRAKRQKDFPYQEILLTRLSMHMHSKLLENRNKMLKAQGINETLFMALITLDAQESRSI
QPSELSAALGSSRTNATRIADELEKKGWIERRESHNDRRCLHLHLTEAGIEFLHQLLPPQHKCLHFLWSTLTEQEQQQLE
MLTRKLLTRLDQMEISEQ
>Mature_178_residues
MKLMRRLIMESSFSPIEQMLNSRAKRQKDFPYQEILLTRLSMHMHSKLLENRNKMLKAQGINETLFMALITLDAQESRSI
QPSELSAALGSSRTNATRIADELEKKGWIERRESHNDRRCLHLHLTEAGIEFLHQLLPPQHKCLHFLWSTLTEQEQQQLE
MLTRKLLTRLDQMEISEQ

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=166, Percent_Identity=80.1204819277108, Blast_Score=272, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 20992; Mature: 20992

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMRRLIMESSFSPIEQMLNSRAKRQKDFPYQEILLTRLSMHMHSKLLENRNKMLKAQG
CHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INETLFMALITLDAQESRSIQPSELSAALGSSRTNATRIADELEKKGWIERRESHNDRRC
CCHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LHLHLTEAGIEFLHQLLPPQHKCLHFLWSTLTEQEQQQLEMLTRKLLTRLDQMEISEQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLMRRLIMESSFSPIEQMLNSRAKRQKDFPYQEILLTRLSMHMHSKLLENRNKMLKAQG
CHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INETLFMALITLDAQESRSIQPSELSAALGSSRTNATRIADELEKKGWIERRESHNDRRC
CCHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LHLHLTEAGIEFLHQLLPPQHKCLHFLWSTLTEQEQQQLEMLTRKLLTRLDQMEISEQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]