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The map label for this gene is can [H]

Identifier: 22124692

GI number: 22124692

Start: 872565

End: 873497

Strand: Reverse

Name: can [H]

Synonym: y0779

Alternate gene names: 22124692

Gene position: 873497-872565 (Counterclockwise)

Preceding gene: 22124697

Following gene: 22124689

Centisome position: 18.99

GC content: 43.94

Gene sequence:

>933_bases
TTGGTCAACTGCGTTATTTCCAGTGCATATGTCATAAGTAAAAAGGAACCTTATTCAATGGGGCTCTTGGTGGTCCTGCG
TACCCATGAAGTATTTAACCCTCCCCACATGAGGGACGTTACGGGTAACATAAAAAATCAAACAGGCACCGAGAAGATAT
TACGCAGACAATATCGCGTTATTACCGAAACTACTGTTCCGATTTCAAAATCGGAATCCTTGCCGTATATTATTCTATCG
CAACCCGAACACTACAGGCTATTTACATTGATGAAAGAAATAGAAAAGCTCATCGCGAACAATCGAACTTGGTCAAATAC
CATTTGTAAAGATGATCCCGGTTTTTTTGAGCACTTGGCACAATCTCAGAAACCGCGCTTCTTATGGATTGGTTGTTCAG
ACAGTCGCGTTCCCGCAGAGCAGTTAACTGGATTGAAATCAGGCGAGTTATTTGTTCACCGTAACGTTGCCAATCTGGTT
ATCCATACCGATCTTAACTGCCTATCGGTCGTCCAATACGCTATTGATGTTCTTCAGGTAGAACACATTATTATCTGTGG
CCACCTTGGCTGTGGTGGTGTTGAAGCGGCCATCAAAGGCGAAGAGATGGGGCTTATCGATAACTGGTTACTGCACATTC
GGGACCTTTGGTATAAACACAGTTCATTGTTGGGTGAACTGCCACAAGAAGAACGCAGTAATGTGTTGTGTCAGATAAAC
GTGGTAGAGCAAGTGTATAACCTTGGTCATTCAACCATTGTGCGTTCAGCCTGGAAGCGCGGGCAAAAAGCCATGATCCA
CGGCTGGGTATATGGTATTGAAAATGGCCTGCTGCGTGATTTAGAAGTCTCAGCCACCAGCCTTGGTAGCCTGGAAATGG
TGTATCGCAAAGCAATGGCTGAGTTATTACAAAACAATAAAGAAGACCATTAA

Upstream 100 bases:

>100_bases
GGATTTCCCCGCCCCATTCGGCCCGAGCAGAGCATAAAAGTCGCCTGCCTCTACGTGCAGATCGATACCACGCAGTGCCT
GAACGCCACCCATATAGGTT

Downstream 100 bases:

>100_bases
GTCGCTCTGGGAGGGTACGTTAAAACGCGCCCTCTCCCACAAAACCCTTCCGCTAAATTAAGCGTCCCAGCGCGCAAGAA
CCGGAGCGTACATGCAGTAC

Product: carbonic anhdrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVNCVISSAYVISKKEPYSMGLLVVLRTHEVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILS
QPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLV
IHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQIN
VVEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Sequences:

>Translated_310_residues
MVNCVISSAYVISKKEPYSMGLLVVLRTHEVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILS
QPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLV
IHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQIN
VVEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
>Mature_310_residues
MVNCVISSAYVISKKEPYSMGLLVVLRTHEVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILS
QPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLV
IHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQIN
VVEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=73.1132075471698, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1786534, Length=174, Percent_Identity=35.0574712643678, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=212, Percent_Identity=31.6037735849057, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 35231; Mature: 35231

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNCVISSAYVISKKEPYSMGLLVVLRTHEVFNPPHMRDVTGNIKNQTGTEKILRRQYRV
CCEEEEECEEEEECCCCCCCCEEEEEEEHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
ITETTVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLA
HHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
QSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQV
HCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHH
EHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQIN
CEEEEEECCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEE
VVEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMA
HHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHH
ELLQNNKEDH
HHHHCCCCCC
>Mature Secondary Structure
MVNCVISSAYVISKKEPYSMGLLVVLRTHEVFNPPHMRDVTGNIKNQTGTEKILRRQYRV
CCEEEEECEEEEECCCCCCCCEEEEEEEHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
ITETTVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLA
HHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
QSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQV
HCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHH
EHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQIN
CEEEEEECCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEE
VVEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMA
HHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHH
ELLQNNKEDH
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]