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The map label for this gene is aegA [H]

Identifier: 22124513

GI number: 22124513

Start: 676119

End: 678134

Strand: Direct

Name: aegA [H]

Synonym: y0599

Alternate gene names: 22124513

Gene position: 676119-678134 (Clockwise)

Preceding gene: 22124511

Following gene: 22124514

Centisome position: 14.7

GC content: 52.93

Gene sequence:

>2016_bases
ATGAATCCATTTATTGTTGCTGACGCTGAGAGCTGTATTGGTTGTCGGAGTTGTGAAGTGGCTTGTGTGGTCGCCCATCA
TGAGGGCCAGTTTCCTGATAAACCGGAATATTTCACCCCACGGGTGAAAGTATTCAAAGGCGATCAATGTGCGACGGCAG
TATTTTGCCATCATTGTGAAGATGCCCCTTGTGCCAGCACCTGCCCGAATGGTGCCATTGTTGAATTGAATAATCGTGTT
CAGGTGATTCAGGAAAAATGTATTGGCTGTAAAACCTGTATGATCGCCTGCCCGTTTGGCATGATGACCGTAGTCACCGA
AACGGTTCAACCCGCCAGCCACCGCTTAGCGGATGTCTATCGGCGTACAGAAGCACAAAAATGTGACCTTTGTCTTGATC
AGCCTGATGGCCCTGCCTGTATTAAAACCTGCCCTACGCAGGCTCTGACCTTGGTGGACCAACAATATTTACTGCATCAA
CAGCAGCAAAAGCGCCAACACATGGCGCTGAATGAGCACAATGGCCGCTTGTTCAGTCGCGCGGTGGTACAGGCGGCCAG
TGCATCGTCAAATAAAAGCATCCGCGACGCAACACCGGTTAACCTCTTGCAGCGGCCACGGGCACCACGTCTGGAGCCGA
AAAAAATTCCGTTGGCAGAGCGTAAAACGGGTTTTGCTGAAATCTATCTGCCATTTACCGAAAGCCAAATCCATGAACAG
GCTGAACGCTGCCTGGAATGCGGTGATAAAACCATATGTCAGTGGACATGCCCACTGCATAACGCCATCCCGAAATGGAT
CTCGCTGGCCCATCAGGGGCGGATCCATGAAGCAGCAGAATTATCCCATCAAACCAGCAGCTTGCCCGAAGTGTGTGGCC
GGGTATGCCCGCAAGATCGCTTATGTGAGCAGTCCTGTACGCTGAATGACCACGATGGCGCGGTCACTATCGGGCAGATT
GAGCGGCATATCACGGAAACGGCACTGGCGACCGGCTGGCGGCCTGATCTGTCACAGGTGAAACCCAGCGGTAAACGGGT
CGCTATTATTGGCGCTGGCCCAGCAGGTTTGGGCTGTGCGGATATTCTGGTACGTAATGGCATCACGCCAGTGGTGTTTG
ATCGTTATCCCGAAATTGGCGGTTTGCTGACATTTGGTATTCCGGCTTTCAAGCTGGAAAAATCGGTGATGACTCGGCGG
AGAGAAATTTTCACCGAGATGGGCGTGGAGTTTTGCCTGAATACAGAAATTGGCCGCGATATCACCATGGAAAACCTGCT
CCACGACTTCGATGCTCTGTTCCTCGGGGTTGGGACCTACCGTTCCATGCGCTCAGGATTAGAAAATGAGGATGCTCAGG
GCGTTTACGATGCCTTGCCATTCCTGATCGGTAACACCCAGCATTTGATGGGTTACACCGCCAATGGCGCTCACCCTTAT
GTCAGTATGCAGGACCAACGCGTGGTGGTGTTGGGGGGCGGTGATACCGCCATGGATTGTGTTCGAACCTCCCTGCGTCA
GGGGGCAAGCCGCGTAGTGTGCGCGTATCGGCGTGATGAGAAGAATATGCCTGGTTCTAAACGTGAGGTGAAAAATGCGC
GTGAGGAGGGGGCTGAATTTATGTTCAACCTCCAGCCGATGAGCATTGTGGTCGATGAATCGGGACAGGTGACGGGTATC
AAGATGGTTCGCACTGAAATGGGACAGGCAGATGCCCAAGGGCGGCGACAAGCCCTGCCTATCACCGGTTCCGAGCATCT
TATTCCTGCTGATGCCGTGATCATGGCCTTTGGTTTCAGCCCGCACCGGATGTCATGGCTGGCAGAACATAACGTGGTGC
TGGATAAACAGGGGCGCGTGGTTGCGCCGACTATCTCCGGCTATCCCTATCAAACCAGTAATCCCAAAATTTTTGCCGGT
GGCGACATTGTGCGAGGAGCTGACTTGATTGTGACCGCCATCGCGGAGGGGCGCAAAGCGGCAGAGAGTATTGCGTATTA
TTTGAACGTTTTATAA

Upstream 100 bases:

>100_bases
ATTATGTTTATAAGGTTAATTATGGGATAAGCATTGTGACGAGTTGTTGCAAATAATAACTATTTATCCGGCAATGGCAT
GACTTCTGGGAAGAAATATA

Downstream 100 bases:

>100_bases
CGCCTGCGGCCAGGAGAGAAAGATGAACCGTTTTGTTATCGCTGATATGACTCAGTGCATTGGCTGCCGGACCTGTGAAA
TCGCCTGTGTGGTGGCGCAT

Product: putative oxidoreductase Fe-S binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNRV
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDALPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPITGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL

Sequences:

>Translated_671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNRV
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDALPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPITGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL
>Mature_671_residues
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCEDAPCASTCPNGAIVELNNRV
QVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVYRRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQ
QQQKRQHMALNEHNGRLFSRAVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDRLCEQSCTLNDHDGAVTIGQI
ERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCADILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRR
REIFTEMGVEFCLNTEIGRDITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDALPFLIGNTQHLMGYTANGAHPY
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEFMFNLQPMSIVVDESGQVTGI
KMVRTEMGQADAQGRRQALPITGSEHLIPADAVIMAFGFSPHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAG
GDIVRGADLIVTAIAEGRKAAESIAYYLNVL

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=452, Percent_Identity=29.8672566371681, Blast_Score=165, Evalue=2e-40,
Organism=Escherichia coli, GI1788811, Length=670, Percent_Identity=56.4179104477612, Blast_Score=794, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=470, Percent_Identity=69.1489361702128, Blast_Score=694, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=666, Percent_Identity=51.6516516516517, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI1788468, Length=442, Percent_Identity=32.579185520362, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1789067, Length=173, Percent_Identity=52.6011560693642, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI2367245, Length=167, Percent_Identity=47.9041916167665, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1789243, Length=469, Percent_Identity=30.2771855010661, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87082179, Length=164, Percent_Identity=43.2926829268293, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1789079, Length=197, Percent_Identity=36.0406091370558, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87082114, Length=198, Percent_Identity=33.8383838383838, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787749, Length=180, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790326, Length=165, Percent_Identity=31.5151515151515, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI2367345, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787122, Length=165, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787872, Length=163, Percent_Identity=27.6073619631902, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17570289, Length=480, Percent_Identity=34.5833333333333, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71984108, Length=474, Percent_Identity=29.746835443038, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17543860, Length=260, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320030, Length=465, Percent_Identity=31.8279569892473, Blast_Score=218, Evalue=2e-57,
Organism=Drosophila melanogaster, GI28574881, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24665539, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24665547, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24665543, Length=473, Percent_Identity=36.1522198731501, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640763, Length=456, Percent_Identity=29.1666666666667, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI18858217, Length=456, Percent_Identity=29.1666666666667, Blast_Score=165, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 73781; Mature: 73781

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCE
CCCEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
DAPCASTCPNGAIVELNNRVQVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVY
CCCCCCCCCCCCEEEECCHHHHHHHHHCCHHHHEEECCCHHHHHHHHHHCHHHHHHHHHH
RRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQQQQKRQHMALNEHNGRLFSR
HHHCCCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHH
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDR
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCHHH
LCEQSCTLNDHDGAVTIGQIERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCA
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCCCHH
DILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRRREIFTEMGVEFCLNTEIGRD
HHHHHCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCC
ITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDALPFLIGNTQHLMGYTANGAHPY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCCE
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEF
EEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
MFNLQPMSIVVDESGQVTGIKMVRTEMGQADAQGRRQALPITGSEHLIPADAVIMAFGFS
EEECCCEEEEEECCCCEEEEEHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEEECCC
PHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAGGDIVRGADLIVTAIAEGRKA
HHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHH
AESIAYYLNVL
HHHHHHHHHCC
>Mature Secondary Structure
MNPFIVADAESCIGCRSCEVACVVAHHEGQFPDKPEYFTPRVKVFKGDQCATAVFCHHCE
CCCEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
DAPCASTCPNGAIVELNNRVQVIQEKCIGCKTCMIACPFGMMTVVTETVQPASHRLADVY
CCCCCCCCCCCCEEEECCHHHHHHHHHCCHHHHEEECCCHHHHHHHHHHCHHHHHHHHHH
RRTEAQKCDLCLDQPDGPACIKTCPTQALTLVDQQYLLHQQQQKRQHMALNEHNGRLFSR
HHHCCCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AVVQAASASSNKSIRDATPVNLLQRPRAPRLEPKKIPLAERKTGFAEIYLPFTESQIHEQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHH
AERCLECGDKTICQWTCPLHNAIPKWISLAHQGRIHEAAELSHQTSSLPEVCGRVCPQDR
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCHHH
LCEQSCTLNDHDGAVTIGQIERHITETALATGWRPDLSQVKPSGKRVAIIGAGPAGLGCA
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCCCHH
DILVRNGITPVVFDRYPEIGGLLTFGIPAFKLEKSVMTRRREIFTEMGVEFCLNTEIGRD
HHHHHCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCC
ITMENLLHDFDALFLGVGTYRSMRSGLENEDAQGVYDALPFLIGNTQHLMGYTANGAHPY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCCE
VSMQDQRVVVLGGGDTAMDCVRTSLRQGASRVVCAYRRDEKNMPGSKREVKNAREEGAEF
EEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
MFNLQPMSIVVDESGQVTGIKMVRTEMGQADAQGRRQALPITGSEHLIPADAVIMAFGFS
EEECCCEEEEEECCCCEEEEEHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEEECCC
PHRMSWLAEHNVVLDKQGRVVAPTISGYPYQTSNPKIFAGGDIVRGADLIVTAIAEGRKA
HHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHH
AESIAYYLNVL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]