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The map label for this gene is tatD [H]

Identifier: 22124370

GI number: 22124370

Start: 506492

End: 507031

Strand: Direct

Name: tatD [H]

Synonym: y0455

Alternate gene names: 22124370

Gene position: 506492-507031 (Clockwise)

Preceding gene: 22124369

Following gene: 22124371

Centisome position: 11.01

GC content: 48.52

Gene sequence:

>540_bases
ATGTTTGATATTGGTGTTAATTTAACCAGCGTACAGTTTGCAAAAGATTATCATCAGGTAGTCAACCGGGCAAAAGAGGC
TGGGGTTCTCGGTATCCTGATTACCGGTACTGATGCAGATGAAAGCTTGGCAGCACAGACTTTGGCCGCTGAATACCCTG
GCTATTGTTGGTCGACTACAGGCGTTCATCCTCACCATGCGAGCAGTTGGCAAGATAGTGTCGAGCAGAAAATTCGAACC
TTGGCAGCCACTGCCTCCGTCGTCGGTATTGGTGAGTGCGGGTTAGACTTTAACCGTAACTTTTCCACCCCAGCGCAACA
AGAAGTCGCATTTACCGCTCAATTAGCTCTGGCTGCCGAACTTTCGCTGCCGGTATTTTTGCATTGTCGTGATGCCCATG
AGCGTTTTATTGATTTGCTGGTTCCTTGGCTAGATAAAATACCGGCGGCTGTTGTGCATTGTTTCACGGGTAACAGTGAT
TGTAACGAACGGTGCAATAGTGATCCACACCCAACGCCTGAAATCAGATCCAGGGGGTAA

Upstream 100 bases:

>100_bases
ACTGAAGAAGATGAAGGTATAGATAGCCATCCGAAAGCACCTTAAATCGATGCGTTGATATTTAGCCGCCCTTCTGGGCG
GTTTCTGTTTTGGAACACTT

Downstream 100 bases:

>100_bases
TCTGCTCTCCTGATTCAGGAGAGTTTATGGTCACTTTTGAGACAGTTATGGAAATTAAAATCCTGCACAAGCAGGGAATG
AGTAGCCGGGCGATTGCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MFDIGVNLTSVQFAKDYHQVVNRAKEAGVLGILITGTDADESLAAQTLAAEYPGYCWSTTGVHPHHASSWQDSVEQKIRT
LAATASVVGIGECGLDFNRNFSTPAQQEVAFTAQLALAAELSLPVFLHCRDAHERFIDLLVPWLDKIPAAVVHCFTGNSD
CNERCNSDPHPTPEIRSRG

Sequences:

>Translated_179_residues
MFDIGVNLTSVQFAKDYHQVVNRAKEAGVLGILITGTDADESLAAQTLAAEYPGYCWSTTGVHPHHASSWQDSVEQKIRT
LAATASVVGIGECGLDFNRNFSTPAQQEVAFTAQLALAAELSLPVFLHCRDAHERFIDLLVPWLDKIPAAVVHCFTGNSD
CNERCNSDPHPTPEIRSRG
>Mature_179_residues
MFDIGVNLTSVQFAKDYHQVVNRAKEAGVLGILITGTDADESLAAQTLAAEYPGYCWSTTGVHPHHASSWQDSVEQKIRT
LAATASVVGIGECGLDFNRNFSTPAQQEVAFTAQLALAAELSLPVFLHCRDAHERFIDLLVPWLDKIPAAVVHCFTGNSD
CNERCNSDPHPTPEIRSRG

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=177, Percent_Identity=35.0282485875706, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI225903439, Length=135, Percent_Identity=35.5555555555556, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI225903424, Length=103, Percent_Identity=33.0097087378641, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI48994985, Length=165, Percent_Identity=64.2424242424242, Blast_Score=216, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17559024, Length=157, Percent_Identity=42.6751592356688, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24648690, Length=167, Percent_Identity=33.5329341317365, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221330018, Length=187, Percent_Identity=33.1550802139037, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24586117, Length=163, Percent_Identity=33.7423312883436, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 19477; Mature: 19477

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIGVNLTSVQFAKDYHQVVNRAKEAGVLGILITGTDADESLAAQTLAAEYPGYCWSTT
CEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEECC
GVHPHHASSWQDSVEQKIRTLAATASVVGIGECGLDFNRNFSTPAQQEVAFTAQLALAAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLPVFLHCRDAHERFIDLLVPWLDKIPAAVVHCFTGNSDCNERCNSDPHPTPEIRSRG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDIGVNLTSVQFAKDYHQVVNRAKEAGVLGILITGTDADESLAAQTLAAEYPGYCWSTT
CEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEECC
GVHPHHASSWQDSVEQKIRTLAATASVVGIGECGLDFNRNFSTPAQQEVAFTAQLALAAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLPVFLHCRDAHERFIDLLVPWLDKIPAAVVHCFTGNSDCNERCNSDPHPTPEIRSRG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]