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The map label for this gene is wecD [H]

Identifier: 22124283

GI number: 22124283

Start: 411486

End: 412280

Strand: Direct

Name: wecD [H]

Synonym: y0368

Alternate gene names: 22124283

Gene position: 411486-412280 (Clockwise)

Preceding gene: 22124282

Following gene: 161484902

Centisome position: 8.94

GC content: 51.19

Gene sequence:

>795_bases
GTGCGGCAACCGCGCTGGCGAAAACCGGTTATGGCAAATATCTGTTGGATCTATTACATGCCCGTCCACGCCAGTATTGA
GCCACTGGGCTGGGAAAGTGAATTTTTCCAGCGCCAAAGTGCAAAATTGATTTTTTCCGACTCAGCCCCGCCACTTAACC
CGGCTGAGTTGGCTGCTTTTACTCTCGTTCAGGCTAAAGTACCTACTCATCGCCTTGATCTTATAGATGCCCTGAGCCAA
CTTGATTTTCATTTGGTTGAAGGGGAAATTGATCTGTCGCTGGTCGTGGGTGAAAAAGAAGGTATTGGCACGGAAAATGC
TACATCAGAACCCAATATGGGGGCCTACTCGCTACGGGTTGCCACCGAGGCAGATATTCCGCAGTTGCGCCGTGTTGCTG
CCAGTGCTTTTGCCTTAAGCCGCTTTCGTGCGCCTTGGTATGACGCACAGGACAGTGGGCGATTTTATGCTTTGTGGGTT
GAAAAGGCGGTGCTGGGAACCTTTGATCACCAATGTTTATTGGTGCTCGACCCTACGGATCAACCCGTCGGGTTTGTGAC
GTTGCGTGACTTGCAAGACGGGAGTGCGCGTATTGGCCTGTTGGCCGTATTCCCCGGTGCACAGAGTAAAGGTATAGGGT
TAAGATTAATGTCGGCGGCGAAGCAGTGGTGCCAGCATCATGGGTTACACCGGTTACGGGTAGCCACACAAATGAGCAAT
ATTGCTGCTTTACGTCTCTATATTCGTAGTGGTGCCTCCATTGAGAGTACCGCGTATTGGTTATGCAGGGGATGA

Upstream 100 bases:

>100_bases
ACTTTTGTTCAAACGGTTGAAAAACGCCAAGGTTTTAAAATTGCTTGTTTGGAAGAGATTGCCTGGCGTAACGGTTGGTT
GGATGATGATGGCGTAAAAC

Downstream 100 bases:

>100_bases
GATGATTCCATTTAACACTCCACCGATAGTGGGCACTGAACTGGGTTATATGCAGGCTGCGATGAGCAGTGGCAAGTTAT
GCGGTGATGGTGGTTTTACC

Product: TDP-fucosamine acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRQPRWRKPVMANICWIYYMPVHASIEPLGWESEFFQRQSAKLIFSDSAPPLNPAELAAFTLVQAKVPTHRLDLIDALSQ
LDFHLVEGEIDLSLVVGEKEGIGTENATSEPNMGAYSLRVATEADIPQLRRVAASAFALSRFRAPWYDAQDSGRFYALWV
EKAVLGTFDHQCLLVLDPTDQPVGFVTLRDLQDGSARIGLLAVFPGAQSKGIGLRLMSAAKQWCQHHGLHRLRVATQMSN
IAALRLYIRSGASIESTAYWLCRG

Sequences:

>Translated_264_residues
MRQPRWRKPVMANICWIYYMPVHASIEPLGWESEFFQRQSAKLIFSDSAPPLNPAELAAFTLVQAKVPTHRLDLIDALSQ
LDFHLVEGEIDLSLVVGEKEGIGTENATSEPNMGAYSLRVATEADIPQLRRVAASAFALSRFRAPWYDAQDSGRFYALWV
EKAVLGTFDHQCLLVLDPTDQPVGFVTLRDLQDGSARIGLLAVFPGAQSKGIGLRLMSAAKQWCQHHGLHRLRVATQMSN
IAALRLYIRSGASIESTAYWLCRG
>Mature_264_residues
MRQPRWRKPVMANICWIYYMPVHASIEPLGWESEFFQRQSAKLIFSDSAPPLNPAELAAFTLVQAKVPTHRLDLIDALSQ
LDFHLVEGEIDLSLVVGEKEGIGTENATSEPNMGAYSLRVATEADIPQLRRVAASAFALSRFRAPWYDAQDSGRFYALWV
EKAVLGTFDHQCLLVLDPTDQPVGFVTLRDLQDGSARIGLLAVFPGAQSKGIGLRLMSAAKQWCQHHGLHRLRVATQMSN
IAALRLYIRSGASIESTAYWLCRG

Specific function: Transaminase converting thymidine diphosphate(TDP)-4- keto-6-deoxy-D-glucose to TDP-4-amino-4,6-dideoxy-D-galactose, the immediate precursor of the ECA sugar TDP-Fuc4NAc [H]

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI145693203, Length=244, Percent_Identity=49.5901639344262, Blast_Score=217, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR012752
- InterPro:   IPR016181
- InterPro:   IPR002110
- InterPro:   IPR020683 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 29410; Mature: 29410

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPRWRKPVMANICWIYYMPVHASIEPLGWESEFFQRQSAKLIFSDSAPPLNPAELAAF
CCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHH
TLVQAKVPTHRLDLIDALSQLDFHLVEGEIDLSLVVGEKEGIGTENATSEPNMGAYSLRV
HEEEECCCCHHHHHHHHHHHCCEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEE
ATEADIPQLRRVAASAFALSRFRAPWYDAQDSGRFYALWVEKAVLGTFDHQCLLVLDPTD
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEECCCC
QPVGFVTLRDLQDGSARIGLLAVFPGAQSKGIGLRLMSAAKQWCQHHGLHRLRVATQMSN
CCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
IAALRLYIRSGASIESTAYWLCRG
HHEEEEEECCCCCCCCEEEEEEEC
>Mature Secondary Structure
MRQPRWRKPVMANICWIYYMPVHASIEPLGWESEFFQRQSAKLIFSDSAPPLNPAELAAF
CCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHH
TLVQAKVPTHRLDLIDALSQLDFHLVEGEIDLSLVVGEKEGIGTENATSEPNMGAYSLRV
HEEEECCCCHHHHHHHHHHHCCEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEE
ATEADIPQLRRVAASAFALSRFRAPWYDAQDSGRFYALWVEKAVLGTFDHQCLLVLDPTD
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEECCCC
QPVGFVTLRDLQDGSARIGLLAVFPGAQSKGIGLRLMSAAKQWCQHHGLHRLRVATQMSN
CCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
IAALRLYIRSGASIESTAYWLCRG
HHEEEEEECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 8366065 [H]