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The map label for this gene is insK [H]

Identifier: 22124222

GI number: 22124222

Start: 326762

End: 327361

Strand: Reverse

Name: insK [H]

Synonym: y0305

Alternate gene names: 22124222

Gene position: 327361-326762 (Counterclockwise)

Preceding gene: 22124223

Following gene: 22124219

Centisome position: 7.12

GC content: 45.33

Gene sequence:

>600_bases
ATGAATCAGCACGGGTTACTCAGCCTCATTCGGCGGAAAAAATATCGCTCCTATAGGGCCGATGGTGGCCGGGCATCCGA
TAATCTATTGGCTCGTAATTTTACATCCGAAATCAGTGGATTGAAGTGGTGTACAGATGTCACAGAGTTCCGAGTTGGAG
CACAGAAGCTGTATTTGTCGGTGATACAAGACCTGTTTAATAATGAGATTATTTCTTGGCATATGTCAGAAAGAGCAGCA
TTAATCCTGACGTGCAAGACGCTGGAAAAAGCGCTGAAAGTGAAAGGGAGAAAAGAAGGCCTGATGTTGCACAGCGATCA
GGGCTGGCATTACCGAACGCCGATGTGGCGCTCAATGCTTGTCGAGGCGGGGATAAGGCAAAGTATGTCACGCAAAGGCA
ATTGTTTAGATAATGCAGTGATGGAAAATTTCTTCAGTCACCTGAAAGCCGAGATGTATCACCGTAAGAAGTACGATTCA
GCCACAGTTTTAAAGCGTGACATTGTAGAATATATCCATTATTACAATACAGAGCGCATTAGCCTGAAAACAGGCGGAAT
GAGTCCGGCAGAATACCGGACTCAGGTAGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
CTAAGCAGACGACACGCACAGCGCTACGGTTATCGCCGGATGACGGTCGCACTGAGAAAAGAAGGGTTCACACCTGAATC
ACAAAACGGTGCGAAAACTG

Downstream 100 bases:

>100_bases
AGCAGATGTCCAAGTTTTGGGGTTCAGTGCACTTATGGCCCCATTGGCGGTTGGTTCATCGGAGGCCAGGTGAGCCGTAA
AGCCATAACAACCGAACCCG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAA
LILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDS
ATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ

Sequences:

>Translated_199_residues
MNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAA
LILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDS
ATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ
>Mature_199_residues
MNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAA
LILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDS
ATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=160, Percent_Identity=27.5, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1789981, Length=195, Percent_Identity=49.7435897435897, Blast_Score=196, Evalue=7e-52,
Organism=Escherichia coli, GI1788405, Length=177, Percent_Identity=36.1581920903955, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1787263, Length=177, Percent_Identity=36.1581920903955, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1786753, Length=177, Percent_Identity=36.1581920903955, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1786570, Length=177, Percent_Identity=36.1581920903955, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1786490, Length=177, Percent_Identity=36.1581920903955, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 23233; Mature: 23233

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLS
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSML
HHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHHHH
VEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
SLKTGGMSPAEYRTQVEKQ
EEECCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLS
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSML
HHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHHHH
VEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
SLKTGGMSPAEYRTQVEKQ
EEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]