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The map label for this gene is mchE [H]

Identifier: 22124205

GI number: 22124205

Start: 308017

End: 309333

Strand: Reverse

Name: mchE [H]

Synonym: y0287

Alternate gene names: 22124205

Gene position: 309333-308017 (Counterclockwise)

Preceding gene: 22124210

Following gene: 22124204

Centisome position: 6.72

GC content: 39.33

Gene sequence:

>1317_bases
ATGATGGGTATAACGGAGCGAGGAATGAGCAGCAATCAGATATTCCGCCGGGACGCGGTAGAGTATATTAGAACAAAATG
GTTGGGGAAGGCGCTGTTAACTTCGGGTTATTCCACAACGTTCATAGCTGCTTTATGTGCTATCTTTTTGGTGTTATTAA
TTACTCTTATCATTTATGGAACATACACCCGTAGAATAAACGTTAATGGTGAGGTTATTTCTCAGCCTCACCCCATAAAC
ATTTTTTCTCCCCAACAAGGATTCATTACCAAAAAATGGGTGGAAGTGGGTGATATTGTCCGTAAAGGTCAGCACTTATA
TCAAATTGATGTCAGTCGAACGACCTTTTCAGGTAATGTTAGCCTTAACTCTTTAGAAGCAATAAATAACCAACTTTCTC
AAATTGATAGCATCATCAATAATACACAGAAAAATAAAGAACTTACGCTACTTAATTTACGTCAGCAGCTCGCACAATAC
CAAAAGGCACATAAGAAATCCCAAGAGCTGGTCGATAACGCAGGCAAAGGAATGGATGATATGCGGCGTACAATGGCCAG
TTATGGTACTTACCAACGTCAGGGTCTAATTACTAAAGATCAATTAACCAATCAGCGTTCCCTCTTTTATCAACAACAGA
ATGCCTTTCAAAGCCTGAATACTCAACTGATACAAGAAAGCTTACAGATAGCAAAACTTGAAAGTGAAATCTCTACGCGA
GCATCAGATTTTGATAATGATATCTCTCAGTATTTATTTCAAAAAGGTGATTTAAAGCGTCAATTGGCTGAAGTTGATGC
GAGTGGCATGTTACTCATTAATTCGCCAAGCGATGGCAAGATTGAAAATATGAGTGTGACCCAAGGACAGATGGTCAACG
TAAATGACAGTTTGGTCCAATTGACGCCTTCTGATAATCCCTATTATTGTCTTGTGCTTTGGGTACCAAACAATAGCGTC
CCTTATATAAATACTGGAGACAAAGTCAATATACGCTATGACGCTTTCCCCTTTGAAAAGTTTGGTCAATTTCCTGGGCG
TATAATCTCTATCTCTAATGTCCCCGTTTCACAACAAGAAATAGCCTCATACAATATTGCACCGCGGCTCCCGAACGGTG
GACTCATTGAGCCTTACTATAAAGTCATCGTGGCACTAGACGATATTCATTTTCGTTATCAGTCTAAACCTTTAATGCTA
TCCAATGGCCTTAAAGCTAATGTCACGTTATTCCTTGAAAAAAGGCCTCTTTATCAATGGATGCTATCTCCATTTTATGA
CATCAAGAAAAGTGTAACGGGGCCTGTAAATGAATGA

Upstream 100 bases:

>100_bases
AAATCAAACTGCAATTCGTAAATAATTAAATATACCGAAATAGAGTTACGTGAAAATGATTCAATTAAACCTTCTATTTT
TTGTGATATGTTGATTTGAA

Downstream 100 bases:

>100_bases
TACGCATTTTAACGAGATAAAAAACCGTCTGAATTTTAGCTTTCGTCGTAAAGTCCCACAGGTGCTTCAAACCGAAGCAG
CAGAATGCGGACTTGCCTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MMGITERGMSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPIN
IFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQY
QKAHKKSQELVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTR
ASDFDNDISQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSV
PYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLML
SNGLKANVTLFLEKRPLYQWMLSPFYDIKKSVTGPVNE

Sequences:

>Translated_438_residues
MMGITERGMSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPIN
IFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQY
QKAHKKSQELVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTR
ASDFDNDISQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSV
PYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLML
SNGLKANVTLFLEKRPLYQWMLSPFYDIKKSVTGPVNE
>Mature_438_residues
MMGITERGMSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPIN
IFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQY
QKAHKKSQELVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTR
ASDFDNDISQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSV
PYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLML
SNGLKANVTLFLEKRPLYQWMLSPFYDIKKSVTGPVNE

Specific function: Probably involved, in conjunction with mchF, in the secretion of microcin H47 [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49704; Mature: 49704

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGITERGMSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
TYTRRINVNGEVISQPHPINIFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNV
CEEEEEECCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCC
SLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQELVDNAGKGMDD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTR
HHHHHHHCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDFDNDISQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQ
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCEECEEECCCEEEECCCCEEE
LTPSDNPYYCLVLWVPNNSVPYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQE
ECCCCCCEEEEEEEECCCCCCEEECCCEEEEEEECCCHHHHCCCCCEEEEECCCCCCHHH
IASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANVTLFLEKRPLYQW
HHHCCCCCCCCCCCCCCHHHHHHEEEEHHEEEECCCCEEEECCCCEEEEEEEECCHHHHH
MLSPFYDIKKSVTGPVNE
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMGITERGMSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
TYTRRINVNGEVISQPHPINIFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNV
CEEEEEECCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCC
SLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQELVDNAGKGMDD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTR
HHHHHHHCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDFDNDISQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQ
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCEECEEECCCEEEECCCCEEE
LTPSDNPYYCLVLWVPNNSVPYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQE
ECCCCCCEEEEEEEECCCCCCEEECCCEEEEEEECCCHHHHCCCCCEEEEECCCCCCHHH
IASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANVTLFLEKRPLYQW
HHHCCCCCCCCCCCCCCHHHHHHEEEEHHEEEECCCCEEEECCCCEEEEEEEECCHHHHH
MLSPFYDIKKSVTGPVNE
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11181394 [H]