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The map label for this gene is araB [H]

Identifier: 22124151

GI number: 22124151

Start: 243779

End: 245431

Strand: Reverse

Name: araB [H]

Synonym: y0231

Alternate gene names: 22124151

Gene position: 245431-243779 (Counterclockwise)

Preceding gene: 22124152

Following gene: 22124150

Centisome position: 5.33

GC content: 52.15

Gene sequence:

>1653_bases
TTGAGGGACAAAACAATGGCAAGTTACTTTATCGGCGTAGACGTAGGGACCGGCAGTGCAAGAGCTGGGGTATTCGATTT
GCAGGGCCGTATGGTTGGGCAGGCCAGCCGTGAAATCACCATGTTTAAACCCAAGGCTGATTTTGTTGAGCAGTCTTCCG
AGAATATTTGGCAAGCGGTGTGTAATGCGGTGCGTGATGCGGTTAATCAGGCCGATATCAACCCGATTCAGGTCAAAGGG
CTGGGTTTTGATGCGACTTGCTCGCTGGTGGTGTTGGATAAAGAAGGGAATCCACTGACGGTTAGCCCTTCAGGGCGCAA
TGAGCAAAATGTGATTGTTTGGATGGACCACCGGGCGATCACTCAGGCGGAGCGGATTAATGCCACCAAGCACCCGGTCC
TGGAGTTTGTCGGTGGTGTGATTTCGCCAGAAATGCAGACACCAAAGTTGTTGTGGTTAAAGCAACATATGCCGAACACG
TGGAGTAATGTCGGCCATCTGTTTGATCTACCAGATTTTCTTACCTGGCGTGCCACGAAAGATGAAACCCGTTCGCTCTG
TTCCACCGTCTGCAAATGGACCTATCTGGGCCATGAAGATCGCTGGGATCCGTCCTACTTCAAATTGGTGGGGCTGGCCG
ATTTACTGGATAACAACGCGGCGAAGATCGGTGCGACGGTTAAACCCATGGGGGCACCGTTAGGGCATGGTTTAAGTCAG
CGGGCAGCATCAGAAATGGGGTTGATCCCCGGTACGGCGGTCAGTGTGTCGATTATTGATGCTCACGCTGGGACGATTGG
CATTCTCGGTGCCAGTGGTGTGACGGGGGAAAATGCTAACTTTGATCGGCGGATTGCGCTGATTGGTGGCACCTCTACCG
CCCATATGGCGATGTCGCGCTCAGCACACTTTATCAGTGGTATTTGGGGGCCATATTATTCGGCCATTTTACCGGAATAT
TGGTTGAACGAGGGCGGGCAGTCGGCAACGGGGGCTTTGATTGACCATATTATTCAATCACATCCTTGCTATCCGGCACT
GCTGGAACAGGCTAAAAATAAGGGCGAAACCATCTATGAGGCGCTGAATTATATTTTGCGTCAGATGGCGGGTGAACCTG
AAAATATCGCGTTCCTGACGAATGATATTCATATGTTGCCGTACTTCCACGGTAACCGCTCTCCCCGTGCCAACCCAAAT
CTGACGGGCATTATTACTGGCCTGAAACTCTCTACCACGCCAGAAGATATGGCGCTGCGTTATTTGGCAACCATTCAGGC
GCTGGCGTTGGGCACACGGCATATTATCGAAACCATGAATCAGAATGGCTATAACATCGACACTATGATGGCCAGCGGCG
GAGGCACCAAGAACCCCATATTTGTACAGGAGCATGCGAATGCGACGGGCTGCGCCATGCTGTTGCCAGAAGAGAGTGAG
GCGATGCTGTTGGGGAGTGCCATGATGGGTACCGTCGCTGCTGGGGTGTTTGAGTCATTGCCGGAAGCCATGGCGGCCAT
GAGCCGCATCGGTAAGACCGTGACCCCACAAACCAATAAAATCAAAGCCTATTACGATCGTAAGTACCGGGTATTCCATC
AGATGTATCACGACCATATGCGCTATCAGGCACTGATGCAGGAGGGCGCATGA

Upstream 100 bases:

>100_bases
TGGCCTGAATTTGCTGGGGGTGAGTAGCTACCTGACCATGGCGTTATGGGGTGGGGTACTGATCCTCTTTATCGCATTAC
AGAATCGTAAAGCCTAAGAA

Downstream 100 bases:

>100_bases
GCCAGAATAAGGAGTGGCTGGCAGCCAGTGATGCCTGGATGATCTACAGCCGCGAACTGGCGGCATTAAAAGAGAATGTC
GATCAACAGGTGTGGTTGCA

Product: sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MRDKTMASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAVCNAVRDAVNQADINPIQVKG
LGFDATCSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAITQAERINATKHPVLEFVGGVISPEMQTPKLLWLKQHMPNT
WSNVGHLFDLPDFLTWRATKDETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQ
RAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSRSAHFISGIWGPYYSAILPEY
WLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYEALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPN
LTGIITGLKLSTTPEDMALRYLATIQALALGTRHIIETMNQNGYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESE
AMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHMRYQALMQEGA

Sequences:

>Translated_550_residues
MRDKTMASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAVCNAVRDAVNQADINPIQVKG
LGFDATCSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAITQAERINATKHPVLEFVGGVISPEMQTPKLLWLKQHMPNT
WSNVGHLFDLPDFLTWRATKDETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQ
RAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSRSAHFISGIWGPYYSAILPEY
WLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYEALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPN
LTGIITGLKLSTTPEDMALRYLATIQALALGTRHIIETMNQNGYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESE
AMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHMRYQALMQEGA
>Mature_550_residues
MRDKTMASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAVCNAVRDAVNQADINPIQVKG
LGFDATCSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAITQAERINATKHPVLEFVGGVISPEMQTPKLLWLKQHMPNT
WSNVGHLFDLPDFLTWRATKDETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQ
RAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSRSAHFISGIWGPYYSAILPEY
WLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYEALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPN
LTGIITGLKLSTTPEDMALRYLATIQALALGTRHIIETMNQNGYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESE
AMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHMRYQALMQEGA

Specific function: Unknown

COG id: COG1069

COG function: function code C; Ribulose kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=545, Percent_Identity=49.9082568807339, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI164663830, Length=569, Percent_Identity=47.8031634446397, Blast_Score=548, Evalue=1e-156,
Organism=Escherichia coli, GI1786249, Length=491, Percent_Identity=25.6619144602851, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790005, Length=547, Percent_Identity=20.2925045703839, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789987, Length=534, Percent_Identity=22.0973782771536, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787789, Length=276, Percent_Identity=25.7246376811594, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320314, Length=519, Percent_Identity=37.3795761078998, Blast_Score=366, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6324080, Length=503, Percent_Identity=26.441351888668, Blast_Score=156, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24657106, Length=543, Percent_Identity=46.7771639042357, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24657102, Length=543, Percent_Identity=46.7771639042357, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI21356323, Length=437, Percent_Identity=45.5377574370709, Blast_Score=389, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005929 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.16 [H]

Molecular weight: Translated: 60093; Mature: 60093

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKTMASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAV
CCCCEEEEEEEEEEECCCCCCCCEEECCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
CNAVRDAVNQADINPIQVKGLGFDATCSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAI
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCEEEEEECCHHH
TQAERINATKHPVLEFVGGVISPEMQTPKLLWLKQHMPNTWSNVGHLFDLPDFLTWRATK
HHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCCHHHCCCCCCCCHHHEECCCH
DETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHH
RAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSR
HHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHC
SAHFISGIWGPYYSAILPEYWLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYE
CCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
ALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPNLTGIITGLKLSTTPEDMALR
HHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCEEEEECCEECCCHHHHHHH
YLATIQALALGTRHIIETMNQNGYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEECCCCCC
AMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHM
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
RYQALMQEGA
HHHHHHHHCC
>Mature Secondary Structure
MRDKTMASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAV
CCCCEEEEEEEEEEECCCCCCCCEEECCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
CNAVRDAVNQADINPIQVKGLGFDATCSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAI
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCEEEEEECCHHH
TQAERINATKHPVLEFVGGVISPEMQTPKLLWLKQHMPNTWSNVGHLFDLPDFLTWRATK
HHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCCHHHCCCCCCCCHHHEECCCH
DETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHH
RAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSR
HHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHC
SAHFISGIWGPYYSAILPEYWLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYE
CCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
ALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPNLTGIITGLKLSTTPEDMALR
HHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCEEEEECCEECCCHHHHHHH
YLATIQALALGTRHIIETMNQNGYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEECCCCCC
AMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHM
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
RYQALMQEGA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9084180; 8969504; 9384377; 10417639 [H]