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The map label for this gene is mreB [H]

Identifier: 22124122

GI number: 22124122

Start: 214951

End: 215994

Strand: Reverse

Name: mreB [H]

Synonym: y0202

Alternate gene names: 22124122

Gene position: 215994-214951 (Counterclockwise)

Preceding gene: 22124123

Following gene: 22124121

Centisome position: 4.69

GC content: 52.97

Gene sequence:

>1044_bases
ATGTTTAAGAAATTTCGTGGCATGTTTTCCAACGACTTGTCCATCGACTTGGGTACCGCCAATACCCTTATATATGTTAA
AGGACAAGGCATTGTACTGAATGAGCCTTCAGTGGTGGCTATTCGTCAGGATCGTGCCGGTTCACCAAAGAGCGTTGCAG
CGGTTGGCCATGATGCCAAACAGATGCTGGGGCGTACTCCTGGTAATATCGCGGCTATTCGTCCAATGAAAGACGGCGTT
ATCGCCGATTTCTTTGTCACGGAAAAAATGCTGCAGCACTTTATCAAGCAAGTTCACAGCAACAGCTTCATGCGCCCGAG
TCCGCGCGTGTTGGTGTGCGTGCCGGTCGGGGCTACTCAGGTTGAGCGCCGTGCGATCCGTGAATCTGCCCAGGGCGCAG
GTGCCCGTGAGGTGTTCCTAATTGAAGAGCCGATGGCTGCGGCCATTGGCGCGGGCTTGCCTGTTTCTGAAGCCACCGGT
TCAATGGTTGTGGATATTGGTGGCGGTACCACAGAAGTGGCCGTCATCTCTCTGAACGGGGTGGTTTACTCTTCTTCTGT
GCGTATCGGTGGTGACCGCTTTGATGAAGCTATCATTAATTATGTCCGTCGTAATTACGGTTCATTAATTGGTGAAGCAA
CCGCCGAACGTATCAAACACAGCATTGGTTCTGCTTACCCGGGCGACGAAGTGCTGGAAATCGAAGTGCGTGGTCGTAAC
CTTGCTGAAGGGGTACCACGTGGCTTTACGCTGAATTCCAACGAGATCCTTGAAGCGTTGCAAGAACCGCTGACAGGTAT
TGTGAGCGCAGTTATGGTGGCGCTGGAACAGTGCCCACCAGAATTGGCTTCTGACATCTCTGAGCGCGGTATGGTATTGA
CCGGTGGCGGCGCATTGCTGCGTAACCTGGACCGCCTGCTGATGGAAGAGACCGGTATTCCCGTCGTGGTCGCAGAAGAT
CCATTGACCTGCGTTGCACGTGGTGGCGGTAAAGCGTTGGAAATGATCGACATGCATGGCGGCGATTTGTTCAGCGAAGA
ATAG

Upstream 100 bases:

>100_bases
CCGAGTCAGGACGTTTTTGCGCCTTGTTGCTGATTCGTGTGGTTGGTAAAGTAGGCGGATTTTATTTTTCGCCCCCAGCT
TGCAGGATTATCCTTTCGTT

Downstream 100 bases:

>100_bases
TCAGCCAAAGAAGAGGGCTAGGTCGGTTAAGTCTATACCCAAATTAATTGGGGTTGCAGCAAGTCAGCGAATCCCGATGC
GCTGATCCAGGTCAGTGATT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHSIGSAYPGDEVLEIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE

Sequences:

>Translated_347_residues
MFKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHSIGSAYPGDEVLEIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE
>Mature_347_residues
MFKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHSIGSAYPGDEVLEIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=99.135446685879, Blast_Score=690, Evalue=0.0,
Organism=Escherichia coli, GI1786870, Length=339, Percent_Identity=25.3687315634218, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36902; Mature: 36902

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK
CCCHHHCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCEECCCCHHH
QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHH
VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHSIGSAYPGDEVLEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL
HHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHH
RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK
CCCHHHCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCEECCCCHHH
QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHH
VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHSIGSAYPGDEVLEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL
HHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHH
RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]