BacMap

Definition	Yersinia pestis KIM 10 chromosome, complete genome.
Accession	NC_004088
Length	4,600,755

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The map label for this gene is gabD [H]

Identifier: 22124095

GI number: 22124095

Start: 179440

End: 179778

Strand: Reverse

Name: gabD [H]

Synonym: y0175

Alternate gene names: 22124095

Gene position: 179778-179440 (Counterclockwise)

Preceding gene: 22124096

Following gene: 22124094

Centisome position: 3.91

GC content: 52.21

Gene sequence:

>339_bases
GTGATTGCAGATGCCAATGAGCAGATGAAAGTGGCCTCGGAAGAGACATTTGGCCCGCTGGCCGCCTGCTTCCGTTTCAG
CACTGAAGCCGAAGTGATTCAACGGGCCAATAATACGCCATTTGGGCTGGCGGCCTATTTCTATACGCAGAACTTGCAAC
GGGTGTTCCGCGTTTCAGAGGCGTTGGAAAGCGGTATGATTGGCGTCAATGAATGCTCGGTTTCGACCGAGTTGGCCCCT
TTCGGTGGTGTTAAAGAGTCTGGCCTAGGTCGTGAAGGTTCGGTGCTGGGGTTGGATGAATTTATGGAAGTGAAAACCCT
GCATTTGGGTAACTTGTAG

Upstream 100 bases:

>100_bases
AGAAAGTAGAAGAGCACGTAAAAGATGCGCTTGAGAAGGGGGGGCGTCTTTTAGCGGGGGGCATCGCCATGCGCTGGGCG
GTAATTTCTTCCAGCCAACG

Downstream 100 bases:

>100_bases
ACAACCTTGTCGGTCGAGTTAATGGGTTAGCGTTAAGTATGAGTTGTAATAATGATGTGTGATATGAATAGTCATAATGA
TATGAATGGTCCTAATGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: SSDH [H]

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MIADANEQMKVASEETFGPLAACFRFSTEAEVIQRANNTPFGLAAYFYTQNLQRVFRVSEALESGMIGVNECSVSTELAP
FGGVKESGLGREGSVLGLDEFMEVKTLHLGNL

Sequences:

>Translated_112_residues
MIADANEQMKVASEETFGPLAACFRFSTEAEVIQRANNTPFGLAAYFYTQNLQRVFRVSEALESGMIGVNECSVSTELAP
FGGVKESGLGREGSVLGLDEFMEVKTLHLGNL
>Mature_112_residues
MIADANEQMKVASEETFGPLAACFRFSTEAEVIQRANNTPFGLAAYFYTQNLQRVFRVSEALESGMIGVNECSVSTELAP
FGGVKESGLGREGSVLGLDEFMEVKTLHLGNL

Specific function: Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=112, Percent_Identity=50, Blast_Score=107, Evalue=2e-24,
Organism=Homo sapiens, GI25777721, Length=112, Percent_Identity=50, Blast_Score=107, Evalue=2e-24,
Organism=Homo sapiens, GI12007648, Length=108, Percent_Identity=44.4444444444444, Blast_Score=96, Evalue=7e-21,
Organism=Homo sapiens, GI301500698, Length=108, Percent_Identity=44.4444444444444, Blast_Score=96, Evalue=8e-21,
Organism=Homo sapiens, GI25952152, Length=108, Percent_Identity=44.4444444444444, Blast_Score=96, Evalue=9e-21,
Organism=Homo sapiens, GI25777730, Length=104, Percent_Identity=43.2692307692308, Blast_Score=93, Evalue=4e-20,
Organism=Homo sapiens, GI25777726, Length=107, Percent_Identity=41.1214953271028, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI25777724, Length=107, Percent_Identity=41.1214953271028, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI25777728, Length=107, Percent_Identity=41.1214953271028, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI153266822, Length=107, Percent_Identity=41.1214953271028, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI115387104, Length=107, Percent_Identity=40.1869158878505, Blast_Score=90, Evalue=4e-19,
Organism=Homo sapiens, GI21361176, Length=107, Percent_Identity=39.2523364485981, Blast_Score=89, Evalue=5e-19,
Organism=Homo sapiens, GI25777732, Length=107, Percent_Identity=42.0560747663551, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI238814322, Length=111, Percent_Identity=36.9369369369369, Blast_Score=81, Evalue=1e-16,
Organism=Homo sapiens, GI21614513, Length=109, Percent_Identity=36.697247706422, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789015, Length=110, Percent_Identity=56.3636363636364, Blast_Score=137, Evalue=2e-34,
Organism=Escherichia coli, GI1786504, Length=106, Percent_Identity=39.622641509434, Blast_Score=90, Evalue=4e-20,
Organism=Escherichia coli, GI1787558, Length=107, Percent_Identity=36.4485981308411, Blast_Score=83, Evalue=5e-18,
Organism=Escherichia coli, GI87081896, Length=107, Percent_Identity=33.6448598130841, Blast_Score=77, Evalue=2e-16,
Organism=Escherichia coli, GI87082295, Length=99, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI87081926, Length=107, Percent_Identity=34.5794392523364, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1787715, Length=105, Percent_Identity=32.3809523809524, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1787684, Length=109, Percent_Identity=28.4403669724771, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562198, Length=109, Percent_Identity=43.1192660550459, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17534119, Length=101, Percent_Identity=46.5346534653465, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564736, Length=107, Percent_Identity=41.1214953271028, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144435, Length=107, Percent_Identity=41.1214953271028, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25143876, Length=100, Percent_Identity=43, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25143874, Length=100, Percent_Identity=43, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI133930964, Length=109, Percent_Identity=36.697247706422, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71995606, Length=109, Percent_Identity=36.697247706422, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551164, Length=107, Percent_Identity=34.5794392523364, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=102, Percent_Identity=51.9607843137255, Blast_Score=110, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324950, Length=107, Percent_Identity=35.5140186915888, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=110, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323821, Length=109, Percent_Identity=28.4403669724771, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325196, Length=106, Percent_Identity=34.9056603773585, Blast_Score=74, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323822, Length=109, Percent_Identity=27.5229357798165, Blast_Score=71, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321828, Length=99, Percent_Identity=29.2929292929293, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362580, Length=112, Percent_Identity=50.8928571428571, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI62472918, Length=112, Percent_Identity=50.8928571428571, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI62472926, Length=112, Percent_Identity=50.8928571428571, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI62472936, Length=112, Percent_Identity=50.8928571428571, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI21356737, Length=112, Percent_Identity=50.8928571428571, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24650465, Length=109, Percent_Identity=36.697247706422, Blast_Score=88, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129399, Length=107, Percent_Identity=41.1214953271028, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585660, Length=109, Percent_Identity=31.1926605504587, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010102 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.79 [H]

Molecular weight: Translated: 12142; Mature: 12142

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIADANEQMKVASEETFGPLAACFRFSTEAEVIQRANNTPFGLAAYFYTQNLQRVFRVSE
CCCCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ALESGMIGVNECSVSTELAPFGGVKESGLGREGSVLGLDEFMEVKTLHLGNL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIADANEQMKVASEETFGPLAACFRFSTEAEVIQRANNTPFGLAAYFYTQNLQRVFRVSE
CCCCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ALESGMIGVNECSVSTELAPFGGVKESGLGREGSVLGLDEFMEVKTLHLGNL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8297211; 9205837; 9278503 [H]