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The map label for this gene is lptA [H]

Identifier: 22124072

GI number: 22124072

Start: 160867

End: 161433

Strand: Direct

Name: lptA [H]

Synonym: y0152

Alternate gene names: 22124072

Gene position: 160867-161433 (Clockwise)

Preceding gene: 22124071

Following gene: 22124073

Centisome position: 3.5

GC content: 43.74

Gene sequence:

>567_bases
TTGAAAAGGTTAAAACCTCTTATGAAATCCAAAAATAAAATAAGTCATCTTTTACTTGCCTGCTCACTTTTAGCCGCAAG
CCTGTCTGCATTCGCATTAACTGGCGATACAGAACAACCTGCCGAGGTCAAATCCGACAAACAAACATTGGATATGGAAA
CCAATACGGTCACCTTTATTGATAACGTGGTGATCAAACAAGGCACGATCGAGATCAAAGCCGATAAAGTGGTCGTCACG
CGCCCCGGTGGCGATCAAAGTAAAATGATCATTGAAGGCTTTGGTAATCCAGTCACCTTCTACCAGATGCAAGATAGCGG
TAAACCGGTAAAAGGCCATGGGCAGAAATTACGTTACGAAATCGCTAACGACTTTGTGGTACTGACCGGCGATGCCTATC
TGGAACAGCTCGATAGCAATATCAAAGGCGATCGCATCACTTATTTGGTGAAAAAGCAGCAGATGGAAGCCTTTAGTGAT
AAAGGTAAGCGCGTCACTACCGTGTTATTACCGTCTCAATTACAAGATAAAGGGCCAGCAGCATCAGGCCAAAAGAAGAG
TAAGTAA

Upstream 100 bases:

>100_bases
GATGTCGCCTCAGACGATGAAGTGACCCTTTTCGGTATTGGATTTACCTCTGAAGGCATGAGAATACGTGGGAACTTGCG
GGACAAAACCGCTGAGCTGA

Downstream 100 bases:

>100_bases
TCATTTATGGCAACATTAATCGCAGAAAAGCTGGCTAAGGCGTACAAAGGCCGTAAAGTGGTCGAAGACGTTAGCCTAAA
CGTGAAGTCTGGGGAAATTG

Product: lipopolysaccharide transport periplasmic protein LptA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKRLKPLMKSKNKISHLLLACSLLAASLSAFALTGDTEQPAEVKSDKQTLDMETNTVTFIDNVVIKQGTIEIKADKVVVT
RPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYEIANDFVVLTGDAYLEQLDSNIKGDRITYLVKKQQMEAFSD
KGKRVTTVLLPSQLQDKGPAASGQKKSK

Sequences:

>Translated_188_residues
MKRLKPLMKSKNKISHLLLACSLLAASLSAFALTGDTEQPAEVKSDKQTLDMETNTVTFIDNVVIKQGTIEIKADKVVVT
RPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYEIANDFVVLTGDAYLEQLDSNIKGDRITYLVKKQQMEAFSD
KGKRVTTVLLPSQLQDKGPAASGQKKSK
>Mature_188_residues
MKRLKPLMKSKNKISHLLLACSLLAASLSAFALTGDTEQPAEVKSDKQTLDMETNTVTFIDNVVIKQGTIEIKADKVVVT
RPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYEIANDFVVLTGDAYLEQLDSNIKGDRITYLVKKQQMEAFSD
KGKRVTTVLLPSQLQDKGPAASGQKKSK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=167, Percent_Identity=70.059880239521, Blast_Score=252, Evalue=9e-69,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20661; Mature: 20661

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLKPLMKSKNKISHLLLACSLLAASLSAFALTGDTEQPAEVKSDKQTLDMETNTVTFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHCCCCCEECCCCCEEEEE
DNVVIKQGTIEIKADKVVVTRPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYE
EEEEEECCEEEEEECEEEEECCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCEEEEE
IANDFVVLTGDAYLEQLDSNIKGDRITYLVKKQQMEAFSDKGKRVTTVLLPSQLQDKGPA
ECCCEEEEECHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCHHCCCCCC
ASGQKKSK
CCCCCCCC
>Mature Secondary Structure
MKRLKPLMKSKNKISHLLLACSLLAASLSAFALTGDTEQPAEVKSDKQTLDMETNTVTFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHCCCCCEECCCCCEEEEE
DNVVIKQGTIEIKADKVVVTRPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYE
EEEEEECCEEEEEECEEEEECCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCEEEEE
IANDFVVLTGDAYLEQLDSNIKGDRITYLVKKQQMEAFSDKGKRVTTVLLPSQLQDKGPA
ECCCEEEEECHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCHHCCCCCC
ASGQKKSK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]