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The map label for this gene is hdhA [C]

Identifier: 21910917

GI number: 21910917

Start: 1383084

End: 1383266

Strand: Direct

Name: hdhA [C]

Synonym: SpyM3_1381

Alternate gene names: 21910917

Gene position: 1383084-1383266 (Clockwise)

Preceding gene: 21910916

Following gene: 21910918

Centisome position: 72.77

GC content: 36.61

Gene sequence:

>183_bases
ATGACACATACTAAAGAAGTTGCATTTATCACTGGTGCTGCAAGCGGAATTGGAAAACAAATCGGGGAAACCTTATTAAA
AGAAGGTAAAACGGTTGTTTTTTCTGACATTAATCAAGAAAAACTGGATCAGGTTGTTGCTGACTATACTAAAGAAGGCT
ATGACGCTTTTAGTGTTGTGTGA

Upstream 100 bases:

>100_bases
ACCAAGATTACACCTTTGAAGACGTGCAAAACGTTACCGAAGTTACCCTAATTGATAAAACAAACTAAAGACTAACCAAA
AGAAAGACGAGGATAGTATC

Downstream 100 bases:

>100_bases
GATGTCACCAAAGAAGAAGCCATCAATGCTGCTATTGATACGGTTGTTGAAAAATATGGTCGTATTGATATTTTGGTTAA
CAACGCAGGCCTTCAACATG

Product: putative oxidoreductase

Products: acetoacetate; NADH; H+

Alternate protein names: D-Beta-Hydroxybutyrate Dehydrogenase

Number of amino acids: Translated: 60; Mature: 59

Protein sequence:

>60_residues
MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYTKEGYDAFSVV

Sequences:

>Translated_60_residues
MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYTKEGYDAFSVV
>Mature_59_residues
THTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYTKEGYDAFSVV

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.30

Molecular weight: Translated: 6479; Mature: 6348

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYTKEGYDAFSVV
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
THTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYTKEGYDAFSVV
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-3-hydroxybutanoate; NAD+

Specific reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA