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The map label for this gene is lsp [H]

Identifier: 21910092

GI number: 21910092

Start: 609850

End: 610308

Strand: Direct

Name: lsp [H]

Synonym: SpyM3_0556

Alternate gene names: 21910092

Gene position: 609850-610308 (Clockwise)

Preceding gene: 21910091

Following gene: 21910093

Centisome position: 32.09

GC content: 36.17

Gene sequence:

>459_bases
ATGAAAAAACGATTGTTTGTGCTTAGCTTGATCCTCCTTGTAGCTTTGGATCAACTTAGTAAATTTTGGATTGTTTCTCA
TATAGCGCTTGGAGAAGTGAAACCCTTTATCCCAGGTATCGTCAGCTTGACTTACTTGCAAAACAATGGGGCTGCCTTTT
CCATATTGCAGGACCAGCAATGGTTCTTTGTTGTCATAACGGTTTTAGTTATCGGTTATGCTATTTATTACCTTGCTACT
CATCCCCATTTAAATATCTGGAAACAATTAGCTCTCTTGCTTATTATTTCTGGTGGAATCGGGAATTTTATTGATCGTTT
GCGTTTAGCTTACGTGATTGATATGGTTCATTTAGACTTTGTGGATTTTGCCATTTTTAATGTGGCAGATTCATACCTTA
CCGTTGGTGTCATATTATTAGTGATATGTTTATGGAAAGAAGAGGATTATGGAAATTAA

Upstream 100 bases:

>100_bases
TGATTTATGTCAAACGAAAAGATAAAAACCTTTCTGTTGCTGGGGCCACTTTTGTGACTATTTTAAAAGACTATTTTGAT
AAAAGAAGGAAGGCCTTAAC

Downstream 100 bases:

>100_bases
TGTGATAACATCGGGGCAACGCTTGGATAAGGCACTAGCTGATTTAAGTCCCCTGTCACGTGGTCAAGCCAATGACCAAA
TTAAGCAAGGCCTTGTTTTA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLAT
HPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN

Sequences:

>Translated_152_residues
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLAT
HPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN
>Mature_152_residues
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLAT
HPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=142, Percent_Identity=35.9154929577465, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17272; Mature: 17272

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCCEEEEECCCC
WFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMVHLDF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VDFAIFNVADSYLTVGVILLVICLWKEEDYGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCCEEEEECCCC
WFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMVHLDF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VDFAIFNVADSYLTVGVILLVICLWKEEDYGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]