| Definition | Streptococcus pyogenes MGAS315 chromosome, complete genome. |
|---|---|
| Accession | NC_004070 |
| Length | 1,900,521 |
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The map label for this gene is prtS [H]
Identifier: 21909834
GI number: 21909834
Start: 334685
End: 339553
Strand: Direct
Name: prtS [H]
Synonym: SpyM3_0298
Alternate gene names: 21909834
Gene position: 334685-339553 (Clockwise)
Preceding gene: 21909833
Following gene: 21909835
Centisome position: 17.61
GC content: 41.67
Gene sequence:
>4869_bases ATGATGATGACAACAACAGTAGCAGCAGATGAGCTAACCACAACGAGTGAACCAACAATCACGAATCACACTCAACAACA AGCGCAACATCTCACCAATACAGAGTTGAGCTCAGCTGAATCAAAACCTCAAGACACATCACAAATCACTCTCAAGACAA ATCGTGAAAAAGAGCAACCACAAGGTCTAGTCTCTGAGCCAACCACAACTGAGCTAGCTGACACAGATGCAGCACCAATG GCTAATACAGGTCCTGATGCGACTCAAAAAAGCGCTTCTTTACCGCCAGTCAATACAGATGTTCACGATTGGGTAAAAAC CAAAGGAGCTTGGGACAAGGGATACAAAGGACAAGGCAAGGTTGTCGCAGTTATTGACACAGGGATCGATCCGGCCCATC AAAGCATGCGCATCAGTGATGTATCAACTGCTAAAGTAAAATCAAAAGAAGACATGCTAGCACGCCAAAAAGCCGCCGGT ATTAATTATGGGAGTTGGATAAATGATAAAGTTGTTTTTGCACATAATTATGTGGAAAATAGCGATAATATCAAAGAAAA TCAATTCGAGGATTTTGATGAGGACTGGGAAAACTTTGAGTTTGATGCAGAGGCAGAGCCAAAAGCCATCAAAAAACACA AGATCTATCGTCCCCAATCAACCCAGGCACCGAAAGAAACTGTTATCAAAACAGAAGAAACAGATGGTTCACATGATATT GACTGGACACAAACAGACGATGACACCAAATACGAGTCACACGGTATGCATGTGACAGGTATTGTAGCCGGTAATAGCAA AGAAGCCGCTGCTACTGGAGAACGCTTTTTAGGAATTGCACCAGAGGCCCAAGTCATGTTCATGCGTGTTTTTGCCAACG ACGTCATGGGATCAGCTGAATCACTCTTTATCAAAGCTATCGAAGATGCCGTGGCTTTAGGAGCAGATGTGATCAACCTG AGTCTTGGAACCGCTAATGGGGCACAGCTTAGTGGCAGCAAGCCTCTAATGGAAGCAATTGAAAAAGCTAAAAAAGCCGG TGTATCAGTTGTTGTAGCAGCAGGAAATGAGCGCGTCTATGGATCTGACCATGATGATCCATTGGCAACAAATCCAGACT ATGGTTTGGTCGGTTCTCCCTCAACAGGTCGAACACCAACATCAGTGGCAGCTATAAACAGTAAGTGGGTGATTCAACGT CTAATGACGGTCAAAGAATTAGAAAACCGTGCCGATTTAAACCATGGTAAAGCCATCTATTCAGAGTCTGTCGACTTTAA AAACATAAAAGATAGCCTAGGTTATGATAAATCGCATCAATTTGCTTATGTCAAAGAGTCAACTGATGCGGGTTATAACG CACAAGACGTTAAAGGTAAAATTGCTTTAATTGAACGTGATCCCAATAAAACCTATGACGAAATGATTGCTTTGGCTAAG AAACATGGAGCCCTGGGAGTACTTATTTTTAATAACAAGCCTGGTCAATCAAACCGCTCAATGCGTCTAACAGCTAATGG GATGGGGATACCATCTGCTTTCATATCGCACGAATTTGGTAAGGTCATGTCCCAATTAAATGGCAATGGTACAGGAAGTT TAGAGTTTGACAGTGTGGTCTCAAAAGCACCGAGTCAAAAAGGCAATGAAATGAATCATTTTTCAAATTGGGGCCTAACT TCTGATGGCTATTTAAAACCTGACATTACTGCACCAGGTGGCGATATCTACTCTACCTATAACGATAACCACTATGGTAG CCAAACAGGAACAAGTATGGCCTCTCCTCAGATTGCTGGCGCCAGCCTTTTGGTCAAACAATACCTAGAAAAGACTCAGC CAAACTTGCCAAAAGAAAAAATTGCTGATATCGTTAAGAACCTATTGATGAGCAATGCTCAAATTCATGTTAATCCAGAG ACAAAAACGACCACCTCACCGCGTCAGCAAGGGGCAGGATTACTTAATATTGACGGAGCTGTCACTAGCGGCCTTTATGT GACAGGAAAAGACAACTATGGCAGTATATCATTAGGCAACATCACAGATACGATGACGTTTGATGTGACTGTTCACAACC TAAGCAATAAAGCCAAAACATTACGTTATGACACAGAATTGCTAACAGATCATGTAGACCCACAAAAGGGCCGCTTCACC TTGACTTCTCGCTCCTTAAAAACGTACCAAGGAGGAGAAGTTACAGTCCCAGCTAATGGAAAAGTGACTGTAAGGGTTAC CATGGATGTCTCACAGTTCACAAAAGAGCTAACAAAACAGATGCCAAATGGTTACTATCTAGAAGGTTTTGTCCGCTTTA GAGATAGTCAAGATGACCAACTAAATAGAGTAAACATTCCTTTTGTTGGTTTTAAAGGACAATTTGAAAACTTAGCAGTT GCAGAAGAGTCCATTTACAGGTTAAAATCTCAAGGCAAAACCGGTTTTTACTTTGATGAATCAGGTCCAAAAGACGATAT CTATGTCGGTAAACACTTTACAGGACTCGTCACTCTTGGTTCAGAGACCAATGTGTCAACCAAAATGATTTCTGACAATG GTCTACACACACTTGGCACCTTTAAAAATGCAGATGGCAAATTTATCTTAGAAAAAAATGCCCAAGGAAACCCTGTCTTA GCCATTTCTCCAAATGGTGATAACAACCAAGATTTTGCAGCCTTCAAAGGTGTTTTCTTGAGAAAATATCAAGGCTTAAA AGCAAGTGTCTACCATGCTAGTGACAAGGAACACAAAAATCCACTGTGGGTCAGCCCAGAAAGCTTTAAAGGAGATAAAA ACTTTAATAGTGACATTAGATTTGCAAAATCGACGACCCTGTTAGGCACAGCGTTTTCTGGAAAATCGTTAACAGGAGCT GAATTACCAGATGGGTATTATCATTATGTGGTGTCTTATTACCCAGATGTGGTCGGTGCCAAACGTCAAGAAATGACATT TGACATGATTTTAGACCGACAAAAACCGGTACTATCACAAGCAACATTTGATCCTGAAACAAACCGATTCAAACCAGAAC CCCTAAAAGACCGTGGATTAGCTGGTGTTCGCAAAGACAGTGTCTTTTATCTAGAAAGAAAAGACAACAAGCCTTATACA GTTACGATAAACGATAGCTACAAATATGTCTCAGTAGAAGACAGTAAAACATTTGTGGAGCGACAAGCTGATGGCAGCTT TATCTTGCCGCTTGATAAAGCAAAATTAGGGGATTTCTATTACATGGTCGAGGATTTTGCAGGGAACGTGGCCATTGCTA AGTTAGGAGATCACCTACCACAAACATTAGGTAAAACACCAATTAAACTTAAGCTTACAGACGGTAATTATCAGACCAAA GAAACGCTTAAAGATAATCTTGAAATGACACAGTCTGACACAGGTCTAGTCACAAATCAAGCCCAGCTAGCAGTGGTGCA CCGCAATCAGCCGCAAAGCCAGCTAACAAAGATGAATCAGGATTTCTTTATCTCACCAAACGAAGATGGGAATAAAGACT TCGTGGCCTTTAAAGGCTTGAAAAATAACGTGTATAATGACTTAACGGTTAACGTATACGCTAAAGATGACCACCAAAAA CAAACCCCTATCTGGTCTAGTCAAGCAGGCGCTAGTGCATCCGCTATTGAAAGTACAGCCTGGTATGGCATAACAGCCCG AGGAAGCAAGGTGATGCCAGGTGATTATCAGTATGTTGTGACCTATCGTGACGAACATGGTAAAGAACATCAAAAGCAGT ACACCATATCTGTGAATGACAAAAAACCAATGATCACTCAGGGACGTTTTGATACCATTAATGGCGTTGACCACTTTACT CCTGACAAGACAAAAGCCCTTGGCTCATCAGGCATTGTCCGCGAAGAAGTCTTTTACTTGGCCAAGAAAAATGGCCGTAA ATTTGATGTGACAGAAGGTAAAGATGGTATCACAGTTAGTGACAATAAGGTGTATATCCCTAAAAATCCAGATGGTTCTT ACACCATTTCAAAAAGAGATGGTGTCACACTGTCAGATTATTACTACCTTGTCGAAGATAGAGCTGGTAATGTGTCTTTT GCTACCTTGCGTGACCTAAAAGTGGTCGGAAAAGACAAAGCAGTAGTCAACTTTGGATTAGACTTACCGGTCCCTGAAGA CAAACAAATAGTGAACTTTACCTACCTTGTGCGGGATGCAGATGGTAAACCGATTGAAAACCTAGAGTATTATAATAACT CAGGTAACAGTCTTATCTTGCCATATGGCAAATACACGGTCGAATTGTTGACCTATGACACCAATGCAGCCAAACTAGAG TCAGATAAAATCGTTTCCTTTACCTTATCAGCTGATAATAACTTCCAACAAGTTACCTTTAAGATGACGATGTTAGCAAC TTCTCAAATAACTGCCCACTTTGATCATCTTTTGCCAGAAGGCAGTCGCGTTAGCCTTAAAACAGCTCAAGGTCAGCTGA TCCCGCTTGAACAGTCCTTGTATGTGCCTAAAGCTTATGGCAAAACCGTTCAAGAAGGTACTTACGAAGTTGTTGTCAGC CTGCCTAAAGGCTACCGTATCGAAGGCGACACAAAGGTGAATGCCCTACCAAATGAAGTGCACGAACTATCATTACGCCT TGTCAAAGTAGGAGATGCCTCAGATTCAACTGGTGATCATAAGGTTATGTCAAAAAATAATTCACAGGCTTTGACAGCCT CTGCCACACCAACCAAGACAACGACCTCAGCAACAGCAAAAGCCCTACCATCAGCGGGTGAAAAAATGGGTCTCAAGTTG CGCATAGTAGGTCTTGTGTTACTCGGACTTACTTGCGTCTTTAGCCGAAAAAAATCAACCAAAGATTGA
Upstream 100 bases:
>100_bases AAAACATTTAGGAGGGTATCAGGTGGAGAAAAAGCAACGTTTTTCCCTTAGAAAATACAAATCAGGAACGTTTTCGGTCT TAATAGGAAGCGTTTTCTTG
Downstream 100 bases:
>100_bases TAACAAAGCGCAAAGAGACAACAAATCATCCCTTTTAACAGTCTGACCTTTCTTTGAGATTGAGCTGGCAGATGATCATT TTTTAACAAAAGTTAAAGAG
Product: putative cell envelope proteinase
Products: NA
Alternate protein names: SCP [H]
Number of amino acids: Translated: 1622; Mature: 1622
Protein sequence:
>1622_residues MMMTTTVAADELTTTSEPTITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQPQGLVSEPTTTELADTDAAPM ANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLARQKAAG INYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDI DWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIEDAVALGADVINL SLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQR LMTVKELENRADLNHGKAIYSESVDFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAK KHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKVMSQLNGNGTGSLEFDSVVSKAPSQKGNEMNHFSNWGLT SDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPE TKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKGRFT LTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRDSQDDQLNRVNIPFVGFKGQFENLAV AEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKMISDNGLHTLGTFKNADGKFILEKNAQGNPVL AISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLGTAFSGKSLTGA ELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYT VTINDSYKYVSVEDSKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTK ETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLKNNVYNDLTVNVYAKDDHQK QTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFT PDKTKALGSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRAGNVSF ATLRDLKVVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSGNSLILPYGKYTVELLTYDTNAAKLE SDKIVSFTLSADNNFQQVTFKMTMLATSQITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVS LPKGYRIEGDTKVNALPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAKALPSAGEKMGLKL RIVGLVLLGLTCVFSRKKSTKD
Sequences:
>Translated_1622_residues MMMTTTVAADELTTTSEPTITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQPQGLVSEPTTTELADTDAAPM ANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLARQKAAG INYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDI DWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIEDAVALGADVINL SLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQR LMTVKELENRADLNHGKAIYSESVDFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAK KHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKVMSQLNGNGTGSLEFDSVVSKAPSQKGNEMNHFSNWGLT SDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPE TKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKGRFT LTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRDSQDDQLNRVNIPFVGFKGQFENLAV AEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKMISDNGLHTLGTFKNADGKFILEKNAQGNPVL AISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLGTAFSGKSLTGA ELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYT VTINDSYKYVSVEDSKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTK ETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLKNNVYNDLTVNVYAKDDHQK QTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFT PDKTKALGSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRAGNVSF ATLRDLKVVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSGNSLILPYGKYTVELLTYDTNAAKLE SDKIVSFTLSADNNFQQVTFKMTMLATSQITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVS LPKGYRIEGDTKVNALPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAKALPSAGEKMGLKL RIVGLVLLGLTCVFSRKKSTKD >Mature_1622_residues MMMTTTVAADELTTTSEPTITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQPQGLVSEPTTTELADTDAAPM ANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLARQKAAG INYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDI DWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIEDAVALGADVINL SLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQR LMTVKELENRADLNHGKAIYSESVDFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAK KHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKVMSQLNGNGTGSLEFDSVVSKAPSQKGNEMNHFSNWGLT SDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPE TKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKGRFT LTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRDSQDDQLNRVNIPFVGFKGQFENLAV AEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKMISDNGLHTLGTFKNADGKFILEKNAQGNPVL AISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLGTAFSGKSLTGA ELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYT VTINDSYKYVSVEDSKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTK ETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLKNNVYNDLTVNVYAKDDHQK QTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFT PDKTKALGSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRAGNVSF ATLRDLKVVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSGNSLILPYGKYTVELLTYDTNAAKLE SDKIVSFTLSADNNFQQVTFKMTMLATSQITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVS LPKGYRIEGDTKVNALPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAKALPSAGEKMGLKL RIVGLVLLGLTCVFSRKKSTKD
Specific function: This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant [H]
COG id: COG1404
COG function: function code O; Subtilisin-like serine proteases
Gene ontology:
Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S8 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000209 - InterPro: IPR022398 - InterPro: IPR015500 - InterPro: IPR010435 - InterPro: IPR003137 - InterPro: IPR001899 [H]
Pfam domain/function: PF06280 DUF1034; PF02225 PA; PF00082 Peptidase_S8 [H]
EC number: =3.4.21.110 [H]
Molecular weight: Translated: 178290; Mature: 178290
Theoretical pI: Translated: 6.48; Mature: 6.48
Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMMTTTVAADELTTTSEPTITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQP CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCCC QGLVSEPTTTELADTDAAPMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGK CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC VVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVEN EEEEEECCCCCHHHCEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECC SDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDI CCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCC DWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAE CCCCCCCCCCHHHCCCEEEEEEECCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHCCCHH SLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVY HHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEC GSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIY CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEC SESVDFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAK CCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHH KHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKVMSQLNGNGTGSLEFDSVV CCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHH SKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAG HHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCH ASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDGA HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEECCC VTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKGRFT CCCCEEEEECCCCCCEEECCCCEEEEEEEEEECCCCCCCEEEECHHHHHCCCCCCCCEEE LTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRDSQDDQ EEECCEEEECCCEEEECCCCEEEEEEEECHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC LNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLG CCEECCCEEECCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCCEEEEEEEC SETNVSTKMISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQDFAAFKGVFL CCCCCEEEEECCCCCEEECCEECCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH RKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLGTAFSGKSLTGA HHHCCCEEEEEECCCCCCCCCEEECCHHCCCCCCCCCCEEEEECEEEEEEEECCCCCCCC ELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPLKDRGL CCCCCCEEEEEECCCHHHCCCHHHEEHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCC AGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDSKTFVERQADGSFILPLDKAKLGDFY CCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCCHHHHHHCCCCCEEEEECCCCCCCEE YMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKETLKDNLEMTQSDTGLVTNQ EEEEHHCCCEEEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCEEECC AQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLKNNVYNDLTVNVYAKDDHQK EEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCC QTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYTISVND CCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECC KKPMITQGRFDTINGVDHFTPDKTKALGSSGIVREEVFYLAKKNGRKFDVTEGKDGITVS CCCCEECCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEC DNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRAGNVSFATLRDLKVVGKDKAVVNFGL CCEEEECCCCCCCEEEECCCCCEEEEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEECC DLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSGNSLILPYGKYTVELLTYDTNAAKLE CCCCCCCCEEEEEEEEEECCCCCCCCCCCEECCCCCEEEEECCCEEEEEEEECCCCCEEC SDKIVSFTLSADNNFQQVTFKMTMLATSQITAHFDHLLPEGSRVSLKTAQGQLIPLEQSL CCCEEEEEEECCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHCC YVPKAYGKTVQEGTYEVVVSLPKGYRIEGDTKVNALPNEVHELSLRLVKVGDASDSTGDH CCCHHHCCHHHCCCEEEEEECCCCEEECCCCEECCCCHHHHEEEEEEEEECCCCCCCCCC KVMSKNNSQALTASATPTKTTTSATAKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKST EEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCHHCCEEEEHHHHHHHHHHHHHHCCCCC KD CC >Mature Secondary Structure MMMTTTVAADELTTTSEPTITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQP CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCCC QGLVSEPTTTELADTDAAPMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGK CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC VVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVEN EEEEEECCCCCHHHCEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECC SDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDI CCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCC DWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAE CCCCCCCCCCHHHCCCEEEEEEECCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHCCCHH SLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVY HHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEC GSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIY CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEC SESVDFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAK CCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHH KHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKVMSQLNGNGTGSLEFDSVV CCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHH SKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAG HHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCH ASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDGA HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEECCC VTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKGRFT CCCCEEEEECCCCCCEEECCCCEEEEEEEEEECCCCCCCEEEECHHHHHCCCCCCCCEEE LTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRDSQDDQ EEECCEEEECCCEEEECCCCEEEEEEEECHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC LNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLG CCEECCCEEECCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCCEEEEEEEC SETNVSTKMISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQDFAAFKGVFL CCCCCEEEEECCCCCEEECCEECCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH RKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLGTAFSGKSLTGA HHHCCCEEEEEECCCCCCCCCEEECCHHCCCCCCCCCCEEEEECEEEEEEEECCCCCCCC ELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPLKDRGL CCCCCCEEEEEECCCHHHCCCHHHEEHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCC AGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDSKTFVERQADGSFILPLDKAKLGDFY CCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCCHHHHHHCCCCCEEEEECCCCCCCEE YMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKETLKDNLEMTQSDTGLVTNQ EEEEHHCCCEEEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCEEECC AQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLKNNVYNDLTVNVYAKDDHQK EEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCC QTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYTISVND CCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECC KKPMITQGRFDTINGVDHFTPDKTKALGSSGIVREEVFYLAKKNGRKFDVTEGKDGITVS CCCCEECCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEC DNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRAGNVSFATLRDLKVVGKDKAVVNFGL CCEEEECCCCCCCEEEECCCCCEEEEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEECC DLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSGNSLILPYGKYTVELLTYDTNAAKLE CCCCCCCCEEEEEEEEEECCCCCCCCCCCEECCCCCEEEEECCCEEEEEEEECCCCCEEC SDKIVSFTLSADNNFQQVTFKMTMLATSQITAHFDHLLPEGSRVSLKTAQGQLIPLEQSL CCCEEEEEEECCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHCC YVPKAYGKTVQEGTYEVVVSLPKGYRIEGDTKVNALPNEVHELSLRLVKVGDASDSTGDH CCCHHHCCHHHCCCEEEEEECCCCEEECCCCEECCCCHHHHEEEEEEEEECCCCCCCCCC KVMSKNNSQALTASATPTKTTTSATAKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKST EEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCHHCCEEEEHHHHHHHHHHHHHHCCCCC KD CC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA