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The map label for this gene is aroF [H]

Identifier: 161485750

GI number: 161485750

Start: 598493

End: 599659

Strand: Direct

Name: aroF [H]

Synonym: SpyM3_0544

Alternate gene names: 161485750

Gene position: 598493-599659 (Clockwise)

Preceding gene: 21910079

Following gene: 21910081

Centisome position: 31.49

GC content: 41.99

Gene sequence:

>1167_bases
TTGCGTTATTTAACAGCAGGAGAATCTCATGGGCCATCCTTAACAGCTATTATTGAAGGTATACCAGCAGGATTAACTCT
TCATCCAGCGGATATTGATCACGAATTACAGCGACGTCAAGGAGGTTATGGCCGTGGTGCCAGAATGTCTATTGAGACTG
ATCGGGTTCAAATATCCTCAGGAGTTCGTCATGGCAAAACAACAGGGGCCCCCATTACCTTAACGGTAATTAATAAGGAT
CACCAAAAATGGCTAGATGTCATGGCTGTAGGAGACATTGAAGAGACTCTCAAGTTAAAGCGTCGTGTTAAGCATCCTAG
ACCAGGACATGCGGATTTGGTAGGAGGTATTAAATATCATTTTAACGATTTAAGAGATGCCTTAGAGCGTTCCTCGGCTA
GAGAAACAACGATGAGAGTGGCTGTAGGCGCTGTTGCTAAACGTATCTTAGCTGAACTTGGAATTGATATGTTACATCAT
ATCTTAATATTTGGTGGTATAACGATCACAATACCTTCTAAGCTCTCTTTTAGAGAGCTGCAAGAAAGGGCTCTCCATTC
AGAATTATCTATTGTTAATCCAAAGCAAGAAAAAGAAATTAAAACGTATATTGATAAGATAAAAAAAGAAGGGGATACCA
TTGGTGGTATTATTGAAACGATAGTTCAAGGGGTGCCAGCAGGTCTTGGATCTTATGTCCAATGGGATAAAAAATTAGAT
GCCAAGCTGGCTCAAGCAGTTCTTTCCATTAATGCTTTTAAAGGGGTGGAATTTGGAGTTGGGTTTGATATGGGATTCCA
AAAGGGCTCTCAGGTAATGGATGAAATCACCTGGACACCTACCCAAGGCTATGGTCGTCAAACAAACCACTTAGGTGGCT
TTGAAGGTGGCATGACCACAGGACAACCTCTTGTTGTTAAAGGGGTTATGAAGCCCATTCCTACTTTGTATAAACCACTC
ATGTCGGTAGATATTGATAGTCATGAACCTTATAAAGCAACGGTGGAACGCTCTGATCCGACGGCCTTACCAGCTGCAGG
GGTTATCATGGAAAATGTGGTGGCGACGGTGCTTGCCAAAGAGATTTTAGAGACCTTTTCTTCTACTACCATGTCTGAAT
TGCAAAAAGCTTTTTCGGACTATCGTGCCTACGTCAAGCAATTTTAG

Upstream 100 bases:

>100_bases
TAACTAGTGAATGGTCTAAAAATATTATTTCTACAATAGTTAAGAAATGATGTTTTTAGATTAATGTTTTTAAAATAAGT
GGAACCAAAAAGGAGAAAAA

Downstream 100 bases:

>100_bases
ATAGCGAGATACTGGCTTTTATGGTATCATACAGGTATTAATGAACAAAAGGAGACTGTCATGTCACAGGAAATTTATGA
CTATGCTAATCAACTTGAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF

Sequences:

>Translated_388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
>Mature_388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=38.1868131868132, Blast_Score=181, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6321290, Length=372, Percent_Identity=32.7956989247312, Blast_Score=156, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 42566; Mature: 42566

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISS
CCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCEEHHC
GVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYH
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCCHHHH
QERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTT
HHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILETFSSTTMSELQKAFSDYRAYVKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISS
CCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCEEHHC
GVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYH
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCCHHHH
QERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTT
HHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILETFSSTTMSELQKAFSDYRAYVKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]