| Definition | Streptococcus pyogenes MGAS315 chromosome, complete genome. |
|---|---|
| Accession | NC_004070 |
| Length | 1,900,521 |
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The map label for this gene is murG [H]
Identifier: 161485740
GI number: 161485740
Start: 1201782
End: 1202885
Strand: Reverse
Name: murG [H]
Synonym: SpyM3_1175
Alternate gene names: 161485740
Gene position: 1202885-1201782 (Counterclockwise)
Preceding gene: 21910712
Following gene: 21910710
Centisome position: 63.29
GC content: 40.85
Gene sequence:
>1104_bases TTGTTTAAGAGGAGATGCCTAATGCCTAAGAAGATTTTATTTACAGGTGGTGGAACTGTAGGTCATGTCACCTTGAACCT CATTCTCATACCAAAATTTATCAAGGACGGTTGGGAAGTACATTATATTGGTGATAAAAATGGTATTGAACATATAGAAA TTGAAAAGTCAGGCCTTGACGTGACCTTTCATGCTATCGCGACAGGCAAGCTTAGACGCTATTTTTCATGGCAAAATCTA GCTGATGTTTTTAAGGTTGCACTTGGCCTCCTACAGTCTCTCTTTATTGTTGCCAAGCTTCGCCCTCAAGCCCTTTTTTC CAAAGGTGGTTTTGTCTCAGTACCGCCAGTTGTGGCTGCTAAATTGCTTGGTAAACCAGTCTTTATTCATGAATCAGATC GGTCAATGGGACTAGCAAACAAGATTGCCTACAAATTTGCAACTACCATGTATACCACTTTTGAGCAGGAAGACCAGTTG TCTAAAGTTAAACACCTTGGAGCGGTGACAAAGGTTTTCAAAGATGCCAACCAAATGCCTGAATCAACTCAGTTAGAGGC GGTGAAAGAGTATTTTAGTAGAGACCTAAAAACCCTCTTGTTTATTGGTGGTTCGGCAGGGGCGCATGTGTTTAATCAGT TTATTAGTGATCATCCAGAATTGAAGCAACGTTATAATATCATCAATATTACAGGAGACCCTCACCTTAATGAATTGAGT TCTCATCTGTATCGAGTAGATTATGTTACCGATCTCTATCAACCTTTGATAGCGATGGCTGACCTTGTAGTGACAAGAGG GGGCTCTAATACACTTTTTGAGCTACTGGCAATGGCTAAGCTACACCTCATCGTTCCTCTTGGTAAAGAAGCTAGCCGTG GCGATCAGTTAGAAAATGCCACTTATTTTGAGAAGAGGGGCTACGCTAAACAATTACAGGAACCTGATTTAACTTTGCAT AATTTTGATCAGGCAATGGCTGATTTGTTTGAACATCAGGCTGATTATGAGGCTACTATGTTGGCAACTAAGGAGATTCA GTCACCGGACTTCTTTTATGACCTTTTGAGAGCTGATATTAGCTCCGCGATTAAGGAGAAGTAA
Upstream 100 bases:
>100_bases CCCAAACAGGCGATACTATCTTGCTTAGCCCAGCTAATGCTAGCTGGGATATGTATCCTAATTTTGAGGTTCGTGGGGAT GAATTTTTGGCAACCTTTGA
Downstream 100 bases:
>100_bases ATGGCAAAAGATAAAGAGAAACAAAGTGATGACAAGCTCGTTTTGACAGAGTGGCAAAAGCGTAACATTGAATTTTTAAA GAAAAAGAAGCAGCAAGCTG
Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase
Products: NA
Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]
Number of amino acids: Translated: 367; Mature: 367
Protein sequence:
>367_residues MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLDVTFHAIATGKLRRYFSWQNL ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS SHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
Sequences:
>Translated_367_residues MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLDVTFHAIATGKLRRYFSWQNL ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS SHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK >Mature_367_residues MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLDVTFHAIATGKLRRYFSWQNL ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS SHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]
COG id: COG0707
COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786278, Length=337, Percent_Identity=27.0029673590504, Blast_Score=98, Evalue=7e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006009 - InterPro: IPR004276 - InterPro: IPR007235 [H]
Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]
EC number: =2.4.1.227 [H]
Molecular weight: Translated: 41349; Mature: 41349
Theoretical pI: Translated: 7.91; Mature: 7.91
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLD CCCCCCCCCCEEEEECCCEEEEEEEEEEEEEHHHHCCCEEEEECCCCCCCEEEEECCCCC VTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAA EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCHHHHH KLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDANQMP HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC ESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS CHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHH SHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC TYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADI HHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH SSAIKEK HHHHCCC >Mature Secondary Structure MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHIEIEKSGLD CCCCCCCCCCEEEEECCCEEEEEEEEEEEEEHHHHCCCEEEEECCCCCCCEEEEECCCCC VTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAA EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCHHHHH KLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDANQMP HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC ESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS CHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHH SHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC TYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADI HHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH SSAIKEK HHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11296296 [H]