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The map label for this gene is coaD

Identifier: 21672821

GI number: 21672821

Start: 617470

End: 617967

Strand: Direct

Name: coaD

Synonym: BUsg562

Alternate gene names: 21672821

Gene position: 617470-617967 (Clockwise)

Preceding gene: 21672820

Following gene: 21672823

Centisome position: 96.26

GC content: 22.89

Gene sequence:

>498_bases
ATGAAAAAAATTGCAATATATCCAGGTACGTTTGATCCAATTACATACGGACATTTAGATGTTATAACACGTGCAACAAA
AATTTTTGATAATATCATTATTGCCATTTCAAATAACGTACATAAAAAAACTATTTTTAATTTAAAAGAACGAATAAAAT
TAACTAAACTAGCTACATTTCATCTTAAAAATATAAAAAAAGTAATTGGATTTAATGGTTTGCTCGCTAATTTAGCAAAA
AGGGAAAAAAGTAATATTTTAATTAGAGGAGTACGAACAATATTTGATTTTGATTATGAAATAAAATTAGCAGCTATAAA
TAAACAAATTTATCCTGATTTAGATAGTATTTTTTTTCTTTCTTCTAAAGAAGTATCATTTATATCTTCATCTTTTGTAA
AAGAAATAGCGAAATATCAAGGTAACATTAAACCGTATCTTCCTAAAGAAATACATTTCGCTTTAATAAAAAAATTTAAA
GATATTCCTCAAAAATAA

Upstream 100 bases:

>100_bases
TATATTGCCTTTAAAAAAATAAGAATATTAATTCTTAAAAAATATTATATATTTAATAAATAACTTTAACATAATTGATT
TATAGATAAAAAAATAAAAA

Downstream 100 bases:

>100_bases
ATATTATTTTTTAAAAAATAGGGTATATAAAATATACCCTATTATATTTTTCAAAACATATTTACGTTAAAAAAATCAAT
GAACAAATTTTGAAAATTTT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKKIAIYPGTFDPITYGHLDVITRATKIFDNIIIAISNNVHKKTIFNLKERIKLTKLATFHLKNIKKVIGFNGLLANLAK
REKSNILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFFLSSKEVSFISSSFVKEIAKYQGNIKPYLPKEIHFALIKKFK
DIPQK

Sequences:

>Translated_165_residues
MKKIAIYPGTFDPITYGHLDVITRATKIFDNIIIAISNNVHKKTIFNLKERIKLTKLATFHLKNIKKVIGFNGLLANLAK
REKSNILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFFLSSKEVSFISSSFVKEIAKYQGNIKPYLPKEIHFALIKKFK
DIPQK
>Mature_165_residues
MKKIAIYPGTFDPITYGHLDVITRATKIFDNIIIAISNNVHKKTIFNLKERIKLTKLATFHLKNIKKVIGFNGLLANLAK
REKSNILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFFLSSKEVSFISSSFVKEIAKYQGNIKPYLPKEIHFALIKKFK
DIPQK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=50.9433962264151, Blast_Score=191, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BUCAP (Q9Z613)

Other databases:

- EMBL:   AF108665
- EMBL:   AE013218
- RefSeq:   NP_660888.1
- ProteinModelPortal:   Q9Z613
- SMR:   Q9Z613
- EnsemblBacteria:   EBBUCT00000000420
- GeneID:   1005629
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg562
- GeneTree:   EBGT00050000007752
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   BAPH198804:BUSG562-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19018; Mature: 19018

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAIYPGTFDPITYGHLDVITRATKIFDNIIIAISNNVHKKTIFNLKERIKLTKLATF
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
HLKNIKKVIGFNGLLANLAKREKSNILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFFL
HHHHHHHHHCCHHHHHHHHHHHCCCCHHEEHHHHHCCCCEEEEEEECCCCCCCCHHEEEE
SSKEVSFISSSFVKEIAKYQGNIKPYLPKEIHFALIKKFKDIPQK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIAIYPGTFDPITYGHLDVITRATKIFDNIIIAISNNVHKKTIFNLKERIKLTKLATF
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
HLKNIKKVIGFNGLLANLAKREKSNILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFFL
HHHHHHHHHCCHHHHHHHHHHHCCCCHHEEHHHHHCCCCEEEEEEECCCCCCCCHHEEEE
SSKEVSFISSSFVKEIAKYQGNIKPYLPKEIHFALIKKFKDIPQK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438