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The map label for this gene is aroB

Identifier: 21672784

GI number: 21672784

Start: 573099

End: 574181

Strand: Reverse

Name: aroB

Synonym: BUsg519

Alternate gene names: 21672784

Gene position: 574181-573099 (Counterclockwise)

Preceding gene: 21672785

Following gene: 21672783

Centisome position: 89.51

GC content: 29.82

Gene sequence:

>1083_bases
ATGGAACAATTAAAAGTTGTTTTAGGAAAACGTAGCTATCCTATTAATATTGGATCTAGTATTATTCAAGAAGATAACAT
CTTTTGGCCTTTAAATCCTGGAAATCAAGCTATGTTAATCACAAATAAAACATTAGCTAATCTTTTTAAAGATAAGGTTT
TTTTTCATTTAAGAAAATCTGGAATAAAAATAGATCAAGTAATTCTTTCAGATGGAGAACAATTTAAAACATTAAATGAA
ATGGAAGTAATTATTTCAGCTTTATTAGAAAAAAAACATTCTCGTGATACGACCTTGATCGCATTAGGTGGAGGAGTAAT
AGGTGATCTAACTGGATTTTCAGCATCTATTTATCAGAGAGGTGTACGATTTATTCAAATTCCCACTACTCTTTTATCTC
AAGTAGACGCTTCTGTTGGTGGAAAAACTGGAGTCAATCATTTACTTGGTAAAAATATGGTGGGTTCGTTTTGGCAACCC
TCTTCTGTTATTATTGATATCAATTTTTTAAAAACTCTTCCGTACAATGAACTGGTTTCTGGCATGGCAGAAGTTATTAA
ATACGCTGTTATTTTTGACGCAAATTTTTTTGAATGGTTAGAAGAAAACATTGAAAATTTATTACTATTAAATGATGAAC
TAATGTCTTATTGTATTAAAAAATGTTGCGAATTAAAAGCCCAAATAATTGCTCTTGATGAAAGAGAAAATAATTTTAGA
GCATTATTAAATTTTGGACATACATATGGTCACGCTATTGAAGCACATGCTGGTTATGGAAGTTGGTTACATGGTGAAGC
GATTTCAGTTGGTATGGTAATGGCATCTCGTACATCAGAACTAATAGGATGTTTAAAAAAAACAGATTATAAAAGAATAT
TGTCTTTATTAAAGAAAGCAGGGTTGCCTGTTAAGGGACCTAAAAATATGTCTGCTGCTTCATATTTACCATATATGATG
AGAGATAAAAAAGTTATTTCTGGAGAAATGAGGTTAGTTCTCCCAATTTCTATTGGAAAAGCAAAAATTTATTCTGGAAT
AGATAAAAATATTATTTTAAGTGCCATTAAAGATTCTCAATAA

Upstream 100 bases:

>100_bases
CTGATAATCAAAGTGCTAAATCTGTTGCATATAGTATTATTCATTTATTAGAAAAAATGTAATGGAAATTTAAAAAAAAT
GTTTATAGAGTATAAAAATT

Downstream 100 bases:

>100_bases
AATTTCTAATATTTGAGATTAAAAATGATTTATTATGTTTTTATAAGTTTTTTATTAAAATAAAAATTTAATTTTTTTTA
ATTTTTTCATTTTATATAGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEQLKVVLGKRSYPINIGSSIIQEDNIFWPLNPGNQAMLITNKTLANLFKDKVFFHLRKSGIKIDQVILSDGEQFKTLNE
MEVIISALLEKKHSRDTTLIALGGGVIGDLTGFSASIYQRGVRFIQIPTTLLSQVDASVGGKTGVNHLLGKNMVGSFWQP
SSVIIDINFLKTLPYNELVSGMAEVIKYAVIFDANFFEWLEENIENLLLLNDELMSYCIKKCCELKAQIIALDERENNFR
ALLNFGHTYGHAIEAHAGYGSWLHGEAISVGMVMASRTSELIGCLKKTDYKRILSLLKKAGLPVKGPKNMSAASYLPYMM
RDKKVISGEMRLVLPISIGKAKIYSGIDKNIILSAIKDSQ

Sequences:

>Translated_360_residues
MEQLKVVLGKRSYPINIGSSIIQEDNIFWPLNPGNQAMLITNKTLANLFKDKVFFHLRKSGIKIDQVILSDGEQFKTLNE
MEVIISALLEKKHSRDTTLIALGGGVIGDLTGFSASIYQRGVRFIQIPTTLLSQVDASVGGKTGVNHLLGKNMVGSFWQP
SSVIIDINFLKTLPYNELVSGMAEVIKYAVIFDANFFEWLEENIENLLLLNDELMSYCIKKCCELKAQIIALDERENNFR
ALLNFGHTYGHAIEAHAGYGSWLHGEAISVGMVMASRTSELIGCLKKTDYKRILSLLKKAGLPVKGPKNMSAASYLPYMM
RDKKVISGEMRLVLPISIGKAKIYSGIDKNIILSAIKDSQ
>Mature_360_residues
MEQLKVVLGKRSYPINIGSSIIQEDNIFWPLNPGNQAMLITNKTLANLFKDKVFFHLRKSGIKIDQVILSDGEQFKTLNE
MEVIISALLEKKHSRDTTLIALGGGVIGDLTGFSASIYQRGVRFIQIPTTLLSQVDASVGGKTGVNHLLGKNMVGSFWQP
SSVIIDINFLKTLPYNELVSGMAEVIKYAVIFDANFFEWLEENIENLLLLNDELMSYCIKKCCELKAQIIALDERENNFR
ALLNFGHTYGHAIEAHAGYGSWLHGEAISVGMVMASRTSELIGCLKKTDYKRILSLLKKAGLPVKGPKNMSAASYLPYMM
RDKKVISGEMRLVLPISIGKAKIYSGIDKNIILSAIKDSQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=360, Percent_Identity=60.8333333333333, Blast_Score=476, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6320332, Length=336, Percent_Identity=37.202380952381, Blast_Score=193, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BUCAP (Q8K939)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660851.1
- ProteinModelPortal:   Q8K939
- SMR:   Q8K939
- EnsemblBacteria:   EBBUCT00000000036
- GeneID:   1005654
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg519
- GeneTree:   EBGT00050000008095
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   BAPH198804:BUSG519-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39993; Mature: 39993

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLKVVLGKRSYPINIGSSIIQEDNIFWPLNPGNQAMLITNKTLANLFKDKVFFHLRKS
CCCCEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHC
GIKIDQVILSDGEQFKTLNEMEVIISALLEKKHSRDTTLIALGGGVIGDLTGFSASIYQR
CCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEHHCCCHHHHHHC
GVRFIQIPTTLLSQVDASVGGKTGVNHLLGKNMVGSFWQPSSVIIDINFLKTLPYNELVS
CCEEEEEHHHHHHHHHHHCCCCCCHHHHHCCHHCCCCCCCCEEEEEEEHHHHCCHHHHHH
GMAEVIKYAVIFDANFFEWLEENIENLLLLNDELMSYCIKKCCELKAQIIALDERENNFR
HHHHHHHHHHHCCCHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHEEEEEEECCCCCHH
ALLNFGHTYGHAIEAHAGYGSWLHGEAISVGMVMASRTSELIGCLKKTDYKRILSLLKKA
HHHHCCCHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GLPVKGPKNMSAASYLPYMMRDKKVISGEMRLVLPISIGKAKIYSGIDKNIILSAIKDSQ
CCCCCCCCCCCHHHHCHHHHHCCCEECCCEEEEEEEECCCHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MEQLKVVLGKRSYPINIGSSIIQEDNIFWPLNPGNQAMLITNKTLANLFKDKVFFHLRKS
CCCCEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHC
GIKIDQVILSDGEQFKTLNEMEVIISALLEKKHSRDTTLIALGGGVIGDLTGFSASIYQR
CCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEHHCCCHHHHHHC
GVRFIQIPTTLLSQVDASVGGKTGVNHLLGKNMVGSFWQPSSVIIDINFLKTLPYNELVS
CCEEEEEHHHHHHHHHHHCCCCCCHHHHHCCHHCCCCCCCCEEEEEEEHHHHCCHHHHHH
GMAEVIKYAVIFDANFFEWLEENIENLLLLNDELMSYCIKKCCELKAQIIALDERENNFR
HHHHHHHHHHHCCCHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHEEEEEEECCCCCHH
ALLNFGHTYGHAIEAHAGYGSWLHGEAISVGMVMASRTSELIGCLKKTDYKRILSLLKKA
HHHHCCCHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GLPVKGPKNMSAASYLPYMMRDKKVISGEMRLVLPISIGKAKIYSGIDKNIILSAIKDSQ
CCCCCCCCCCCHHHHCHHHHHCCCEECCCEEEEEEEECCCHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438