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The map label for this gene is ppiD

Identifier: 21672727

GI number: 21672727

Start: 525741

End: 527606

Strand: Direct

Name: ppiD

Synonym: BUsg462

Alternate gene names: 21672727

Gene position: 525741-527606 (Clockwise)

Preceding gene: 21672726

Following gene: 21672729

Centisome position: 81.96

GC content: 18.97

Gene sequence:

>1866_bases
ATGATTAAATATTTAAAATCCCGATTAAATATCATTATAGTTAAATGTATATTGGGAATAATTATTTTATCATTAGTATT
CGGTACTATAAATAATTATTTCAATAGAGATACAACAAGATACATTGCTAAAGTAAACGGAGAGGAAATAAGTTTTATAA
CACTACAAAAAATGTATATTGATGAAAGAAAAAAACAAGAAAAAATATTAGGACAAGATTTTGAGAAAATTAAAAAAAAT
AAAAAATTTAAAGAAGAAACATATAACTATATACTATCTCAACTCATAAATAATATTCTTTTAGAACAATATACTAAAAG
AATGAATTTTAATATACAAGACAACGAAATAAAAAAAATAATATTCAATATACCAATATTTCAAGAAAATAATGAATTTA
ATAAGAAAAAATATTTAAATTATCTTTCATCAAAAAATTTAACACATTATGAATACGTAAGCTTAATTAGAAAAAAACTT
AATACTACATATTTAATAAATGCTATTTCTGAAACAGATTTTATATTAGATAATGAACAAAAAAAGATAATAAAGCTATT
ATCTGAAAAAAGAATTATAAAAAAAGCAATTATAAAAATCAACCCTATTATTAATAATCAGAAAGTAACTGAAAAAGAGA
TAAATAATTATTTTGATCAACATAAAAATGAATTTTATACTCCAGAAAAATTTAAAATCAGTTATATTCAGCTTAAACCT
AATAAATTTAAAATACAATGCAGTAATGAAGAAATAAAAAATTGGTATAAAAAAAATATAGATAAATATTCAAATCAAGA
AAGAAGACAATATAGTATTATTCAAACTAAAACTAAGAATGAAGCATTATCCATTTTATCAGAATTAAAAAAAGGAGAAG
ATTTTTCTAAAATAGCTAAAGAAAAATCAATAGATCCCTTTTCTTCTGAACAAGGAGGAAATATTGGATGGATAACAAAA
AACTTTGTACCAAATGAAATAAAAATTGCTAATTTAGAAAAAATAGATCAAATTTCTAATATTATTAAGTTTAACAATAA
TTTTTTAATAATTAAATTAAATAAAATTTTACCGAAAAAATACAAAAAAATATCTGAAGTATCAGATCTTATTGAAAATG
AAATAAAATATCAAAAATCTTTAAATACATATAAAAAATTAAAAGATAAAATTGCTATAATTGCAAAAAAAAATATTAAT
AGATTTGATTTAATTCTTAAAAAAACTAACATCCTTCCTAAAGAAACGAATTGGTTTGATAAAGACTCTGTTCCTAAAGA
ATTACAAAATCCCATATTAAAAAAAATTATTTTTAAAAAAGGACTATTAGATAGACAAAAAAAACTAAAATCACACTCTG
GTCTAATTGTATTAAATGATCATCAATCTTTTTTATTGAGTATAAAAAATTTTCAAAAAAAAAGAATTAAAAAACTTAAA
GACATTAAAAGAAATATTGTTAATAAACTAAAATATATCAAAGCTGTAGAAAAAACGAAAAATAAATTAAAAAAAATTTT
ATTTCAACTAAAAATTGGAAATGAACACATTTTAAAAAAAGAAAATATTATTTTTGAAGAATATGAAACTGTATCTCGAT
ATGACAAAAATCCAAATATATCTGTAATTTTTGCAATGCCGCATCCAAAAGAAGAGAAAAACGTTTATACTATGTATCAA
AATAAAAACAAAAATTTTGTTATTGCATTATTAGATAAAGTTTATAATGAAAAATTTTCTAACGAAGAAGAGAAGATTAT
TATCAAATATTTAGAAAAAAATAATATCGATGTAACATTTCAATGTTTTCTCCAAAATTTACATAGAAAGGCAACAATTT
TATATAATAAAACAGATAACTTTTAA

Upstream 100 bases:

>100_bases
GATCTAAATTTGGCTGACAAAAAACCGTCAGCCTTTATAATTTAAATAAAAAAATTAAAAATTTCAATATAAAATTGAAA
CTATCTAGGATAGTTATATT

Downstream 100 bases:

>100_bases
CAAGTTAATATAATTATTTTTTAAAAAAAATCATTTATATATTAATTTTTTAAGATTAATTATCAAAATTAAACTTTTCT
TTTAACTTTTTCATATAGTA

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYIDERKKQEKILGQDFEKIKKN
KKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKIIFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKL
NTTYLINAISETDFILDNEQKKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKP
NKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAKEKSIDPFSSEQGGNIGWITK
NFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKKYKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNIN
RFDLILKKTNILPKETNWFDKDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLK
DIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNISVIFAMPHPKEEKNVYTMYQ
NKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTFQCFLQNLHRKATILYNKTDNF

Sequences:

>Translated_621_residues
MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYIDERKKQEKILGQDFEKIKKN
KKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKIIFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKL
NTTYLINAISETDFILDNEQKKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKP
NKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAKEKSIDPFSSEQGGNIGWITK
NFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKKYKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNIN
RFDLILKKTNILPKETNWFDKDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLK
DIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNISVIFAMPHPKEEKNVYTMYQ
NKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTFQCFLQNLHRKATILYNKTDNF
>Mature_621_residues
MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYIDERKKQEKILGQDFEKIKKN
KKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKIIFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKL
NTTYLINAISETDFILDNEQKKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKP
NKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAKEKSIDPFSSEQGGNIGWITK
NFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKKYKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNIN
RFDLILKKTNILPKETNWFDKDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLK
DIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNISVIFAMPHPKEEKNVYTMYQ
NKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTFQCFLQNLHRKATILYNKTDNF

Specific function: PPIases accelerate the folding of proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain

Homologues:

Organism=Escherichia coli, GI1786645, Length=614, Percent_Identity=31.5960912052117, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPID_BUCAP (Q8K987)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660794.1
- ProteinModelPortal:   Q8K987
- EnsemblBacteria:   EBBUCT00000000385
- GeneID:   1005703
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg462
- GeneTree:   EBGT00050000007719
- HOGENOM:   HBG366225
- OMA:   INAISET
- ProtClustDB:   CLSK315500
- BioCyc:   BAPH198804:BUSG462-MONOMER
- InterPro:   IPR000297
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 74141; Mature: 74141

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4046620c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCEEEEEEHHHHHH
DERKKQEKILGQDFEKIKKNKKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKLNTTYLINAISETDFILDNEQ
HEECCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEECCCH
KKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC
NKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAK
CEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
EKSIDPFSSEQGGNIGWITKNFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKK
HCCCCCCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHEECCCEEEEEEHHHCHHH
YKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNINRFDLILKKTNILPKETNWFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHEECCCCCCCCCCCCC
KDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHH
DIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCCCE
SVIFAMPHPKEEKNVYTMYQNKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTF
EEEEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHCCCCHHEEHEEECCCCCCEEH
QCFLQNLHRKATILYNKTDNF
HHHHHHHCCCEEEEEECCCCH
>Mature Secondary Structure
MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCEEEEEEHHHHHH
DERKKQEKILGQDFEKIKKNKKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKLNTTYLINAISETDFILDNEQ
HEECCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEECCCH
KKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC
NKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAK
CEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
EKSIDPFSSEQGGNIGWITKNFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKK
HCCCCCCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHEECCCEEEEEEHHHCHHH
YKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNINRFDLILKKTNILPKETNWFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHEECCCCCCCCCCCCC
KDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHH
DIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCCCE
SVIFAMPHPKEEKNVYTMYQNKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTF
EEEEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHCCCCHHEEHEEECCCCCCEEH
QCFLQNLHRKATILYNKTDNF
HHHHHHHCCCEEEEEECCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438