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The map label for this gene is fis

Identifier: 21672661

GI number: 21672661

Start: 437843

End: 438142

Strand: Reverse

Name: fis

Synonym: BUsg387

Alternate gene names: 21672661

Gene position: 438142-437843 (Counterclockwise)

Preceding gene: 21672662

Following gene: 21672659

Centisome position: 68.3

GC content: 27.67

Gene sequence:

>300_bases
ATGTCAGAAGAGTCAATGGATACAGGATTTTTAGTTATTAATACTAAAGATAAACAAGATAAAACTGTAAAAAAACCTTT
ACGTATATTAATAAAAAAATCCTTAGAAAATTATTTTTTACATTTAGATAAAAGCCAATGTGTCAGTAATCTATATCAAT
TAGTTTTATCTGAACTAGAACAACCATTATTAGACATAATAATGCAACATACGCGCGGAAATCAAACACGAGCCGCTTCT
ATTATGGGTATTAATCGAAGTACCTTGCGAAAAAAATTGAAAAGGTATGGTATGAATTAA

Upstream 100 bases:

>100_bases
AATAACACATCATTTTTTTCAAATTATGATTTATTGTTTTAATAAAGAATTTAATTAATAATATATACACATTAAAAAAG
ATTAAAGAGTCGATCAATCT

Downstream 100 bases:

>100_bases
TTTAAAAATAATATTAAATCCTATGTTTTAAATCCTATTGCACTTTCTATAATTTGTTTAGTACAGAAGGTGCAACTTGA
AATTAATCTTTTTATATCTC

Product: factor-for-inversion stimulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MSEESMDTGFLVINTKDKQDKTVKKPLRILIKKSLENYFLHLDKSQCVSNLYQLVLSELEQPLLDIIMQHTRGNQTRAAS
IMGINRSTLRKKLKRYGMN

Sequences:

>Translated_99_residues
MSEESMDTGFLVINTKDKQDKTVKKPLRILIKKSLENYFLHLDKSQCVSNLYQLVLSELEQPLLDIIMQHTRGNQTRAAS
IMGINRSTLRKKLKRYGMN
>Mature_98_residues
SEESMDTGFLVINTKDKQDKTVKKPLRILIKKSLENYFLHLDKSQCVSNLYQLVLSELEQPLLDIIMQHTRGNQTRAASI
MGINRSTLRKKLKRYGMN

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family

Homologues:

Organism=Escherichia coli, GI1789661, Length=99, Percent_Identity=57.5757575757576, Blast_Score=121, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIS_BUCAP (Q8K9F0)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660728.1
- ProteinModelPortal:   Q8K9F0
- SMR:   Q8K9F0
- EnsemblBacteria:   EBBUCT00000000542
- GeneID:   1005770
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg387
- GeneTree:   EBGT00050000007941
- HOGENOM:   HBG509520
- OMA:   TRAASIM
- BioCyc:   BAPH198804:BUSG387-MONOMER
- HAMAP:   MF_00166
- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- PIRSF:   PIRSF002097
- PRINTS:   PR01591
- PRINTS:   PR01590

Pfam domain/function: PF02954 HTH_8; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 11498; Mature: 11367

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEESMDTGFLVINTKDKQDKTVKKPLRILIKKSLENYFLHLDKSQCVSNLYQLVLSELE
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QPLLDIIMQHTRGNQTRAASIMGINRSTLRKKLKRYGMN
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEESMDTGFLVINTKDKQDKTVKKPLRILIKKSLENYFLHLDKSQCVSNLYQLVLSELE
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QPLLDIIMQHTRGNQTRAASIMGINRSTLRKKLKRYGMN
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438