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The map label for this gene is argF

Identifier: 21672631

GI number: 21672631

Start: 406816

End: 407832

Strand: Direct

Name: argF

Synonym: BUsg356

Alternate gene names: 21672631

Gene position: 406816-407832 (Clockwise)

Preceding gene: 21672627

Following gene: 21672632

Centisome position: 63.42

GC content: 27.24

Gene sequence:

>1017_bases
ATGAATTGTCTTTATCAACGTGACTGTTTAAGATTATTAGATTTTACTACTGCAGAATTAAAACACATTATTACATTATC
TGAAAAATTAAAAAAAACAAAACAAAATCGTCAAGAAATCAAATTACTAAAACAAAAAAACATTGCTTTAATTTTTGAAA
AAGAATCAACTCGTACAAGATGTTCATTTGAAGTTGCCGCTTTTGATCAAGGTGCAAATGTTACTTATCTTGGACCCGGT
AGTACTCATCTTGGAACAAAAGAATCAATTGAGGATACAGCAAGAGTACTCAGTCGTTTATACGATGGAATTCAATATCG
AGGTCATAATCATAAAACAATAGAAATTTTAGCACAGTATTCTACTGTACCAGTCTGGAATGGATTAACTGAAAAATTTC
ATCCTACACAATTAATTGCTGATTTACTAACTATAAAAGAAATTTTTCCAAATAGAAATTTTTCTGATATAAAATGTGCT
TATGTTGGTGATTCGCGTAACAACATAGGAAATAGTCTTTTAGAAGCAGCTTCAATTGTAGGATTAAACTTGTATTTAGT
CTCTCCAAAACAATATTGGCCTGAAAAGAATCTTTTTATTGAATGCAAAAAAATAATAAAAAAAAATCAAGGTAATATAA
TATGTACTGAAAATATCAGCGAGGGTGTTAAAAATGCAGACTTTATCTATACTGATGTTTGGGTTTCTATGGGAGAACAT
CACAAAATATGGAAAGAAAGAATTGAATTATTAAAGAATTATCAAGTAAATGATTCTATGATAAAAATGACAAATAATTC
TAAAGTAAAAATACTGCATTGTTTACCTGCTTTACACGATCAAAAAACAAGTATAGGAAAATCTATATTGAAAAAATATG
GATTAAAAGATGGAATGGAAATCACAGATAATATTTTTCAAAAACATCAAAAAACAATTTTTGAACAAGCAGAAAATAGA
TTACATACTATAAAAGCACTCCTTGTATCAAGTCTTATAAAAGAAATGAATTTTTAA

Upstream 100 bases:

>100_bases
AAATATAAAAAAATATTATATACTATATAATTCTATTTTTTACTTTTAAATTTAACTTCATTAAAAATATATTTTTATCT
AGTTATGGAGTATTCAAGTT

Downstream 100 bases:

>100_bases
AAATTAATTAATATCTTTTATATTAAGAAAAATCATATATAAATATAAACAAAATATGAAAGTTTTAATATATAAAAAAA
TCCTCAATAATTTTTTTTCT

Product: ornithine carbamoyltransferase subunit I

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNCLYQRDCLRLLDFTTAELKHIITLSEKLKKTKQNRQEIKLLKQKNIALIFEKESTRTRCSFEVAAFDQGANVTYLGPG
STHLGTKESIEDTARVLSRLYDGIQYRGHNHKTIEILAQYSTVPVWNGLTEKFHPTQLIADLLTIKEIFPNRNFSDIKCA
YVGDSRNNIGNSLLEAASIVGLNLYLVSPKQYWPEKNLFIECKKIIKKNQGNIICTENISEGVKNADFIYTDVWVSMGEH
HKIWKERIELLKNYQVNDSMIKMTNNSKVKILHCLPALHDQKTSIGKSILKKYGLKDGMEITDNIFQKHQKTIFEQAENR
LHTIKALLVSSLIKEMNF

Sequences:

>Translated_338_residues
MNCLYQRDCLRLLDFTTAELKHIITLSEKLKKTKQNRQEIKLLKQKNIALIFEKESTRTRCSFEVAAFDQGANVTYLGPG
STHLGTKESIEDTARVLSRLYDGIQYRGHNHKTIEILAQYSTVPVWNGLTEKFHPTQLIADLLTIKEIFPNRNFSDIKCA
YVGDSRNNIGNSLLEAASIVGLNLYLVSPKQYWPEKNLFIECKKIIKKNQGNIICTENISEGVKNADFIYTDVWVSMGEH
HKIWKERIELLKNYQVNDSMIKMTNNSKVKILHCLPALHDQKTSIGKSILKKYGLKDGMEITDNIFQKHQKTIFEQAENR
LHTIKALLVSSLIKEMNF
>Mature_338_residues
MNCLYQRDCLRLLDFTTAELKHIITLSEKLKKTKQNRQEIKLLKQKNIALIFEKESTRTRCSFEVAAFDQGANVTYLGPG
STHLGTKESIEDTARVLSRLYDGIQYRGHNHKTIEILAQYSTVPVWNGLTEKFHPTQLIADLLTIKEIFPNRNFSDIKCA
YVGDSRNNIGNSLLEAASIVGLNLYLVSPKQYWPEKNLFIECKKIIKKNQGNIICTENISEGVKNADFIYTDVWVSMGEH
HKIWKERIELLKNYQVNDSMIKMTNNSKVKILHCLPALHDQKTSIGKSILKKYGLKDGMEITDNIFQKHQKTIFEQAENR
LHTIKALLVSSLIKEMNF

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=327, Percent_Identity=32.7217125382263, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI18105007, Length=346, Percent_Identity=22.8323699421965, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=57.2289156626506, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=56.8862275449102, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI2367364, Length=299, Percent_Identity=28.4280936454849, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=331, Percent_Identity=30.8157099697885, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322331, Length=286, Percent_Identity=25.5244755244755, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642586, Length=327, Percent_Identity=24.4648318042813, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OTC_BUCAP (P59100)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660698.1
- ProteinModelPortal:   P59100
- SMR:   P59100
- EnsemblBacteria:   EBBUCT00000000205
- GeneID:   1005799
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg356
- GeneTree:   EBGT00050000007871
- HOGENOM:   HBG579429
- OMA:   GNIICTE
- ProtClustDB:   PRK03515
- BioCyc:   BAPH198804:BUSG356-MONOMER
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 38893; Mature: 38893

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 107-107 BINDING 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCLYQRDCLRLLDFTTAELKHIITLSEKLKKTKQNRQEIKLLKQKNIALIFEKESTRTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
CSFEVAAFDQGANVTYLGPGSTHLGTKESIEDTARVLSRLYDGIQYRGHNHKTIEILAQY
EEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
STVPVWNGLTEKFHPTQLIADLLTIKEIFPNRNFSDIKCAYVGDSRNNIGNSLLEAASIV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GLNLYLVSPKQYWPEKNLFIECKKIIKKNQGNIICTENISEGVKNADFIYTDVWVSMGEH
EEEEEEECCHHHCCCCCHHHHHHHHHHCCCCCEEEECCHHCCCCCCCEEEEHHHHHCCCH
HKIWKERIELLKNYQVNDSMIKMTNNSKVKILHCLPALHDQKTSIGKSILKKYGLKDGME
HHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCCCCH
ITDNIFQKHQKTIFEQAENRLHTIKALLVSSLIKEMNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNCLYQRDCLRLLDFTTAELKHIITLSEKLKKTKQNRQEIKLLKQKNIALIFEKESTRTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
CSFEVAAFDQGANVTYLGPGSTHLGTKESIEDTARVLSRLYDGIQYRGHNHKTIEILAQY
EEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
STVPVWNGLTEKFHPTQLIADLLTIKEIFPNRNFSDIKCAYVGDSRNNIGNSLLEAASIV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GLNLYLVSPKQYWPEKNLFIECKKIIKKNQGNIICTENISEGVKNADFIYTDVWVSMGEH
EEEEEEECCHHHCCCCCHHHHHHHHHHCCCCCEEEECCHHCCCCCCCEEEEHHHHHCCCH
HKIWKERIELLKNYQVNDSMIKMTNNSKVKILHCLPALHDQKTSIGKSILKKYGLKDGME
HHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCCCCH
ITDNIFQKHQKTIFEQAENRLHTIKALLVSSLIKEMNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438