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The map label for this gene is glyQ

Identifier: 21672418

GI number: 21672418

Start: 142755

End: 143633

Strand: Reverse

Name: glyQ

Synonym: BUsg128

Alternate gene names: 21672418

Gene position: 143633-142755 (Counterclockwise)

Preceding gene: 21672422

Following gene: 30410816

Centisome position: 22.39

GC content: 26.51

Gene sequence:

>879_bases
ATGGAAAATAATCATAACAATTTTTCTAATCTAATTACAATTTTACAAGAATATTGGACAGAACAGGAATGCGCTATTTT
TCAACCTTTAGACTTACCGATAGGAGCAGGTACATTCCATAATACAACATTTTTTGGAACCATTGGACCAGAACCCATAC
GAGCAGCATATATACAATCTTGTAGACGTCCTACAGATGGAAGATACGGAAAAAATCCAAATCGTTTACAACATTATTAT
CAATTTCAAGTAATTATAAAACCGCCTTTAAAAAATATTCAAAACATTTATTTAAAATCATTGAATTTACTTAAAATAAG
TGAAAAAAGAAACGATATACGTTTTGTAGAAGACAATTGGGAAAATCCTACATTAGGTGCTTGGGGCATTGGCTGGGAAG
TTTGGCTAAATGGAATGGAAATTACTCAATTTACTTATTTTCAACAAGTAGGTGGATTAGAATGCAATCCTGTAACTGTA
GAAATAACTTATGGTTTAGAAAGAATAGCTATGCACATGCAAAATCAATCAAACGTATATGATCTTATTTGGAGCGAAAA
TAAATTTAAAAAAATTACTTATGGTGATATTTTTCAACAAAATGAAATAGAACAATCCAAATATAATTTTGAATACTCTG
ATATTAATTTGTTATTTGAATATTTTCAAAAATATATATTTGAAGCAAAAAAATTAATAGAATTAAAAAAACCTTTGCTA
TTAGTATCTTATGAAAAAATATTACAAGCAAGTCATGTATTTAATTTACTAGATGCAAGAAAAGCAATATCTTCTAGTGA
ACGTCAAAATTATATTTTAAAAATTCGAAAATTAGCTAAAAAAATTGCACAAGAATATTTATATTCAAGAAAAAAATAA

Upstream 100 bases:

>100_bases
ATACGTAAAAAAATCATTATTAATTATATATAAATATATAAATTATATATAAATATATATAATAAAAATATATCTACTAT
TGCTTCTCTTGGATATAAAA

Downstream 100 bases:

>100_bases
AATTTTTATTATAATTAACGAGAAAAAAATGATAAAAAAAACATTTTTAGTCGAAATAGGAACTGAAGAACTACCTTCTA
ACATCCTTAAAAAAATTATT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MENNHNNFSNLITILQEYWTEQECAIFQPLDLPIGAGTFHNTTFFGTIGPEPIRAAYIQSCRRPTDGRYGKNPNRLQHYY
QFQVIIKPPLKNIQNIYLKSLNLLKISEKRNDIRFVEDNWENPTLGAWGIGWEVWLNGMEITQFTYFQQVGGLECNPVTV
EITYGLERIAMHMQNQSNVYDLIWSENKFKKITYGDIFQQNEIEQSKYNFEYSDINLLFEYFQKYIFEAKKLIELKKPLL
LVSYEKILQASHVFNLLDARKAISSSERQNYILKIRKLAKKIAQEYLYSRKK

Sequences:

>Translated_292_residues
MENNHNNFSNLITILQEYWTEQECAIFQPLDLPIGAGTFHNTTFFGTIGPEPIRAAYIQSCRRPTDGRYGKNPNRLQHYY
QFQVIIKPPLKNIQNIYLKSLNLLKISEKRNDIRFVEDNWENPTLGAWGIGWEVWLNGMEITQFTYFQQVGGLECNPVTV
EITYGLERIAMHMQNQSNVYDLIWSENKFKKITYGDIFQQNEIEQSKYNFEYSDINLLFEYFQKYIFEAKKLIELKKPLL
LVSYEKILQASHVFNLLDARKAISSSERQNYILKIRKLAKKIAQEYLYSRKK
>Mature_292_residues
MENNHNNFSNLITILQEYWTEQECAIFQPLDLPIGAGTFHNTTFFGTIGPEPIRAAYIQSCRRPTDGRYGKNPNRLQHYY
QFQVIIKPPLKNIQNIYLKSLNLLKISEKRNDIRFVEDNWENPTLGAWGIGWEVWLNGMEITQFTYFQQVGGLECNPVTV
EITYGLERIAMHMQNQSNVYDLIWSENKFKKITYGDIFQQNEIEQSKYNFEYSDINLLFEYFQKYIFEAKKLIELKKPLL
LVSYEKILQASHVFNLLDARKAISSSERQNYILKIRKLAKKIAQEYLYSRKK

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=288, Percent_Identity=63.5416666666667, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_BUCAP (Q8KA06)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660485.1
- ProteinModelPortal:   Q8KA06
- SMR:   Q8KA06
- EnsemblBacteria:   EBBUCT00000000336
- GeneID:   1005945
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg128
- GeneTree:   EBGT00050000008062
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   BAPH198804:BUSG128-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34557; Mature: 34557

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNHNNFSNLITILQEYWTEQECAIFQPLDLPIGAGTFHNTTFFGTIGPEPIRAAYIQS
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
CRRPTDGRYGKNPNRLQHYYQFQVIIKPPLKNIQNIYLKSLNLLKISEKRNDIRFVEDNW
HCCCCCCCCCCCHHHHEEEEEEEEEECCCHHHHHHHHHHHCCEEEECCCCCCEEEEECCC
ENPTLGAWGIGWEVWLNGMEITQFTYFQQVGGLECNPVTVEITYGLERIAMHMQNQSNVY
CCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCEE
DLIWSENKFKKITYGDIFQQNEIEQSKYNFEYSDINLLFEYFQKYIFEAKKLIELKKPLL
EEEECCCCEEEEEHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LVSYEKILQASHVFNLLDARKAISSSERQNYILKIRKLAKKIAQEYLYSRKK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENNHNNFSNLITILQEYWTEQECAIFQPLDLPIGAGTFHNTTFFGTIGPEPIRAAYIQS
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
CRRPTDGRYGKNPNRLQHYYQFQVIIKPPLKNIQNIYLKSLNLLKISEKRNDIRFVEDNW
HCCCCCCCCCCCHHHHEEEEEEEEEECCCHHHHHHHHHHHCCEEEECCCCCCEEEEECCC
ENPTLGAWGIGWEVWLNGMEITQFTYFQQVGGLECNPVTVEITYGLERIAMHMQNQSNVY
CCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCEE
DLIWSENKFKKITYGDIFQQNEIEQSKYNFEYSDINLLFEYFQKYIFEAKKLIELKKPLL
EEEECCCCEEEEEHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LVSYEKILQASHVFNLLDARKAISSSERQNYILKIRKLAKKIAQEYLYSRKK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438