| Definition | Bacillus anthracis str. Ames, complete genome. |
|---|---|
| Accession | NC_003997 |
| Length | 5,227,293 |
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The map label for this gene is loN [H]
Identifier: 30264538
GI number: 30264538
Start: 4276826
End: 4279147
Strand: Reverse
Name: loN [H]
Synonym: BA_4702
Alternate gene names: 30264538
Gene position: 4279147-4276826 (Counterclockwise)
Preceding gene: 30264539
Following gene: 30264537
Centisome position: 81.86
GC content: 39.15
Gene sequence:
>2322_bases ATGAATACGAATGAAAGAATCGTACCCCTCCTACCATTAAGAGGCGTTCTCGTATATCCAACGATGGTTCTGCATCTTGA TGTAGGACGTGATAAATCGATACAAGCACTAGAGCAGGCGGCAATGGATGAAAATATCATCTTTTTAGCAATGCAAAAAG AAATGAATATCGATGATCCGAAAGAAGATGACATATATAGTGTAGGTACAGTGGCGAAAGTGAAGCAAATGTTAAAATTG CCGAACGGTACGCTTCGTGTCCTTGTAGAAGGTTTACATAGAGCAGAAGTAGTAGAGTTTATCGAAGAAGAAAATGTAGT GCAAGTTTCTATTAAAACGGTAACTGAAGAAGTGGAAGCTGATTTAGAAGAGAAAGCACTTATGCGTACATTACTGGAGC ATTTCGAACAATATATTAAAGTTTCGAAAAAAGTTTCAAATGAAACATTTGCAACGGTAGCTGATGTAGAAGAGCCAGGA AGATTAGTGGATTTAATTGCTTCTCACTTGCCAATTAAAACGAAGCAGAAACAAGAGATTTTAGAAATCATATCTGTGAA AGAACGATTACATACACTTATTTCAATTATTCAAGATGAACAAGAATTACTTAGTTTAGAAAAGAAAATTGGACAAAAAG TGAAACGTTCAATGGAGCGCACGCAAAAAGAATATTTCTTGCGTGAGCAAATGAAGGCGATTCAAACTGAACTTGGCGAT AAAGAAGGCAAGGGCGGGGAAGTTGAAGAACTTCGTGAGAAAATTGAACAGTCAGGAATGCCTGAAGAAACAATGAAGGC TGCGCTGAAAGAATTAGATCGTTATGAAAAGTTACCAGCAAGTTCTGCGGAGAGCGGTGTTATTCGCAATTATATGGATT GGTTATTAGCACTTCCGTGGACAGACGCAACGGAAGATATGATTGATCTTGCTCATTCGGAAGAGATTTTAAACAAAGAT CATTACGGTCTTGAGAAAGTGAAAGAGCGCGTACTGGAATATTTAGCGGTACAGAAGTTAACGAATTCATTAAAAGGGCC TATCCTTTGTTTAGTAGGGCCACCTGGGGTCGGAAAAACTTCGTTAGCGCGTTCTATTGCGACATCATTAAATCGTAATT TTGTCCGTGTATCCCTTGGTGGTGTGCGTGATGAATCTGAAATTCGTGGTCACCGTCGTACGTACGTTGGAGCAATGCCA GGACGCATTATTCAAGGTATGAAAAAGGCAAAATCAGTTAATCCAGTCTTCTTATTAGATGAGATTGATAAAATGTCTAA CGATTTCCGTGGAGATCCTTCAGCAGCATTACTTGAAGTGTTAGATCCAGAACAAAACCATAACTTCAGTGATCATTATA TTGAAGAACCATATGATCTATCGAAAGTTATGTTTGTAGCAACTGCGAATACACTTTCAAGTATTCCAGGTCCATTACTT GACCGTATGGAAATTATTTCGATTGCTGGCTATACAGAACTTGAAAAAGTTCATATTGCTCGTGAACATTTATTGCCGAA ACAATTACAAGAGCATGGCTTACGAAAAGGTAATTTACAAGTACGTGATGAAGCGCTTCTTGAAATTATTCGCTATTATA CACGTGAGGCTGGTGTTCGTACACTAGAGCGCCAAATTGCAAAGGTTTGTCGTAAAGTAGCAAAAATTATCGTTACAGCA GAACGTAAGCGTATTGTAGTAACAGAGAAAAACGTTGTTGATTTACTTGGTAAGCACATATTCCGTTATGGGCAAGCTGA AAAAACAGACCAAGTTGGTATGGCGACGGGTTTAGCGTATACGGCAGCAGGCGGCGATACACTGGCGATTGAAGTGTCCG TAGCGCCAGGTAAAGGGAAATTAATTTTAACAGGGAAACTTGGGGATGTTATGAAAGAATCCGCACAAGCAGCGTTTAGC TATATTCGTTCTCGTGCAGAAGAGCTTCAGATTGATCCGAATTTCCATGAGAAAAATGATATTCATATTCATGTTCCAGA AGGAGCAGTTCCAAAAGATGGACCGTCAGCAGGTATTACGATGGCAACGGCACTTATTTCTGCGTTAACAGGTATTCCTG TAAGTAAAGAAGTGGGGATGACAGGTGAAATTACACTTCGTGGTCGTGTATTACCGATTGGTGGTTTAAAAGAAAAAACA TTAAGTGCTCACCGCGCAGGTTTAACAAAAATTATTTTACCGGCGGAAAATGAGAAAGATTTAGATGATATTCCAGAGAG CGTAAAAGAAAACCTTACGTTTGTGCTTGCATCTCATTTAGATGAAGTATTGGAGCACGCATTAGTAGGAGTGAAACAAT GA
Upstream 100 bases:
>100_bases ATTTACAGTTGCGGAGAATCTCGGCAATTGCATCTAGATGTATTGTAATATAAAATGGTTGAACAGGAGTTTAATTTATT ATGGAGGTGCTATGTCTAGT
Downstream 100 bases:
>100_bases AAGTAACAAAAGCAGACATTGTAATTAGTGCTGTTAAACCAGAACAATATCCAGACGGTGACTTACCAGAAATCGCATTA GCAGGTCGTTCAAATGTCGG
Product: ATP-dependent protease La 1
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 773; Mature: 773
Protein sequence:
>773_residues MNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQMLKL PNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPG RLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGD KEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPWTDATEDMIDLAHSEEILNKD HYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKTSLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMP GRIIQGMKKAKSVNPVFLLDEIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLL DRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVRTLERQIAKVCRKVAKIIVTA ERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAYTAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFS YIRSRAEELQIDPNFHEKNDIHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKT LSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ
Sequences:
>Translated_773_residues MNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQMLKL PNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPG RLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGD KEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPWTDATEDMIDLAHSEEILNKD HYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKTSLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMP GRIIQGMKKAKSVNPVFLLDEIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLL DRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVRTLERQIAKVCRKVAKIIVTA ERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAYTAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFS YIRSRAEELQIDPNFHEKNDIHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKT LSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ >Mature_773_residues MNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQMLKL PNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPG RLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGD KEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPWTDATEDMIDLAHSEEILNKD HYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKTSLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMP GRIIQGMKKAKSVNPVFLLDEIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLL DRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVRTLERQIAKVCRKVAKIIVTA ERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAYTAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFS YIRSRAEELQIDPNFHEKNDIHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKT LSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=780, Percent_Identity=41.7948717948718, Blast_Score=586, Evalue=1e-167, Organism=Homo sapiens, GI21396489, Length=692, Percent_Identity=42.9190751445087, Blast_Score=556, Evalue=1e-158, Organism=Escherichia coli, GI1786643, Length=767, Percent_Identity=53.7157757496741, Blast_Score=836, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=702, Percent_Identity=39.8860398860399, Blast_Score=514, Evalue=1e-146, Organism=Caenorhabditis elegans, GI17556486, Length=785, Percent_Identity=36.4331210191083, Blast_Score=479, Evalue=1e-135, Organism=Saccharomyces cerevisiae, GI6319449, Length=715, Percent_Identity=38.041958041958, Blast_Score=506, Evalue=1e-144, Organism=Drosophila melanogaster, GI24666867, Length=698, Percent_Identity=43.5530085959885, Blast_Score=562, Evalue=1e-160, Organism=Drosophila melanogaster, GI221513036, Length=698, Percent_Identity=43.5530085959885, Blast_Score=561, Evalue=1e-160,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR008268 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 86214; Mature: 86214
Theoretical pI: Translated: 5.78; Mature: 5.78
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDP CCCCCCEEEECCCCCHHHHCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC KEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEA CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH DLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLVDLIASHLPIKTKQKQEI HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH LEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC KEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPW CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC TDATEDMIDLAHSEEILNKDHYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKT CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH SLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAKSVNPVFLLD HHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHEECCCCHHHHHHHHHHCCCCCEEEHH EIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLL HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHEEEHHHHHHCCCHHH DRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVR HHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHH TLERQIAKVCRKVAKIIVTAERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAY HHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEE TAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFSYIRSRAEELQIDPNFHEKND EECCCCEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC IHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKT EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCHHHH LSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ HHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure MNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDP CCCCCCEEEECCCCCHHHHCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC KEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEA CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH DLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLVDLIASHLPIKTKQKQEI HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH LEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC KEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPW CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC TDATEDMIDLAHSEEILNKDHYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKT CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH SLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAKSVNPVFLLD HHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHEECCCCHHHHHHHHHHCCCCCEEEHH EIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLL HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHEEEHHHHHHCCCHHH DRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVR HHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHH TLERQIAKVCRKVAKIIVTAERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAY HHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEE TAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFSYIRSRAEELQIDPNFHEKND EECCCCEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC IHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKT EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCHHHH LSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ HHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA