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The map label for this gene is ruvB [H]

Identifier: 30264490

GI number: 30264490

Start: 4226718

End: 4227719

Strand: Reverse

Name: ruvB [H]

Synonym: BA_4650

Alternate gene names: 30264490

Gene position: 4227719-4226718 (Counterclockwise)

Preceding gene: 30264491

Following gene: 30264489

Centisome position: 80.88

GC content: 41.42

Gene sequence:

>1002_bases
ATGGACGAACGTCTCCTTTCAGGGGAATCTGCATATGAAGATGCGGATTTAGAATATTCATTACGGCCACAGACGCTCCG
TCAGTATATTGGCCAAGATAAAGCGAAACATAATTTAGAAGTGTTTATTGAAGCGGCGAAAATGCGTGAAGAAACGTTAG
ATCACGTGCTTTTATATGGACCACCAGGACTTGGTAAAACGACGCTTGCGAATATTATTGCCAATGAAATGGGCGTAAAT
GTTAGAACAACTTCAGGTCCAGCAATCGAAAGGCCAGGAGATTTAGCAGCTGTATTAACATCGCTTCAACCAGGGGATGT
ATTATTTATTGATGAAATTCATCGTTTGCATAGATCAATTGAAGAAGTACTATATCCTGCGATGGAAGATTTTTGCCTTG
ATATTGTCATTGGAAAAGGACCGTCAGCGCGATCTGTACGTTTAGATTTACCGCCATTTACATTAGTTGGAGCAACGACG
CGTGCGGGAGCATTATCAGCGCCATTACGTGACCGTTTCGGTGTACTTTCAAGATTAGAGTATTACACAGTAGATCAGCT
TTCTGCGATTGTGGAACGTACAGCAGAAGTATTTGAAGTTGAAATTGATTCGTTAGCTGCACTAGAAATTGCAAGACGTG
CTCGTGGTACACCTCGTATTGCGAATCGTTTATTACGACGTGTACGAGATTTCGCACAAGTTCGTGGTAACGGAACAGTT
ACGATGGAAATTACGCAAATGGCATTAGAATTGCTGCAAGTAGATAAATTAGGTCTAGATCATATTGACCATAAATTATT
GCTTGGTATTATTGAAAAATTCCACGGTGGCCCAGTTGGACTAGAAACGGTTTCGGCAACGATTGGAGAAGAATCTCATA
CGATTGAAGATGTGTATGAGCCATATTTATTACAAATTGGCTTTTTACAACGAACGCCAAGGGGCCGGATTGTAACGCCG
CTTGCATATGAGCATTTCGGAATGGAGATGCCAAAAGTATGA

Upstream 100 bases:

>100_bases
TTTCTCGCGTTGTACCAGAGTTATTAAAAGAATCATTAACGACGGATCAGTATATTAAAAAGGCACTTAGTCTTTTACTA
AATGGTAAGAGGTGAGTATA

Downstream 100 bases:

>100_bases
CGGAGATGCCGAAATTGCTTATTACAGCAGGTATCTTACTTATCGTTGTTGGATTAGCTTGGAAGTTCATTGGAAGGCTT
CCAGGCGATATTTTTGTGAA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVN
VRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTV
TMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTP
LAYEHFGMEMPKV

Sequences:

>Translated_333_residues
MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVN
VRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTV
TMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTP
LAYEHFGMEMPKV
>Mature_333_residues
MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVN
VRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTV
TMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTP
LAYEHFGMEMPKV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=60.7250755287009, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787119, Length=128, Percent_Identity=35.9375, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37036; Mature: 37036

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYG
CCCCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSI
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLE
HHHHHHHHHHHEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
YYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEE
TMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYE
EEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHH
PYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
HHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCC
>Mature Secondary Structure
MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYG
CCCCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSI
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLE
HHHHHHHHHHHEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
YYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEE
TMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYE
EEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHH
PYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
HHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA