Click here to switch to the map view.

The map label for this gene is cpdB [H]

Identifier: 30264201

GI number: 30264201

Start: 3966617

End: 3968941

Strand: Reverse

Name: cpdB [H]

Synonym: BA_4346

Alternate gene names: 30264201

Gene position: 3968941-3966617 (Counterclockwise)

Preceding gene: 30264204

Following gene: 30264198

Centisome position: 75.93

GC content: 36.73

Gene sequence:

>2325_bases
ATGCTGGCTGGAGCAACTCTTGCTATTGGTGTAATGGCGCCGCAAGTATTGCCAGCAACAGCTCATGCGGATGAGAAAAC
TGGGGAGAGTACAGTTAACTTACGAATTCTAGAAACATCAGATATTCACGTTAACTTAATGAATTACGATTATTACCAAA
CGAAAACAGATAATAAAGTAGGTCTTGTGCAAACTGCAACACTTGTTAATAAAGCTCGTGAAGAAGCGAAGAACTCTGTC
CTATTTGATGATGGGGATGCATTACAAGGGACACCGCTTGGAGATTATGTAGCGAATAAAATAAATGATCCGAAGAAGCC
TGTGGATCCTAGTTATACACATCCATTATATCGTTTAATGAATTTAATGAAGTATGACGTCATCTCTCTTGGGAATCATG
AATTTAACTACGGTTTAGATTATTTAAACAAAGTGATTAGTAAAACAGAGTTCCCGGTTATTAACTCAAACGTCTATAAA
GATGATAAAGATAATAATGAAGAGAACGACCAAAATTACTTTAAACCATATCATGTTTTTGAAAAAGAAGTAGAAGATGA
ATCAGGGCAAAAACAAAAAGTGAAAATTGGCGTAATGGGATTTGTTCCACCTCAAGTTATGAACTGGGATAAAGCAAATT
TAGAAGGAAAAGTGAAAGCAAAAGATATAGTTGAAACAGCAAAGAAAATGGTGCCAAAAATGAAAGCAGAAGGTGCAGAT
GTTATCGTTGCACTAGCGCATTCCGGTGTTGATAAGAGTGGATACAACGTCGGTATGGAAAACGCGTCGTATTATTTAAC
AGAGGTTCCTGGTGTAGATGCAGTATTAATGGGACATTCACATACTGAAGTGAAGGATGTATTTAATGGTGTTCCAGTTG
TAATGCCTGGTGTCTTTGGAAGTAACTTAGGTATTATTGATATGCAATTGAAAAAAGTAAATGGAAAATGGGAAGTACAA
AAAGAGCAATCGAAGCCGCAACTTCGTCCGATTGCTGATAGTAAAGGAAACCCACTCGTACAATCTGATCAAAATTTAGT
TAATGAAATTAAAGATGATCATCAAGCGACAATTGATTATGTGAATACAGCTGTAGGAAAAACGACAGCGCCAATTAATA
GTTATTTCTCATTAGTACAAGATGATCCTTCTGTACAACTTGTGACAAATGCACAGAAATGGTATGTAGAAAAGTTATTT
GCTGAAAATGGACAGTATAGTAAATATAAAGGAATTCCAGTTTTATCTGCAGGTGCACCATTTAAAGCAGGTGGCCGAAA
CGGTGCTACATATTATACGGATATTCCAGCTGGAACGTTAGCGATTAAAAACGTTGCAGATTTATATGTATATCCAAATA
CGTTATATGCTGTAAAAGTAAATGGGGCACAAGTAAAAGAATGGCTTGAAATGTCTGCAGGTCAGTTTAATCAAATTGAT
CCAAAGAAAACAGAAGAACAGCCATTAGTAAATATCGGATACCCTACATATAACTTTGATATTTTAGATGGCTTAAAATA
CGAAATTGATGTAACACAACCAGCGAAATACGATAAAGATGGAAAAGTTGTAAATGCTAATACGAATCGTATTATAAATA
TGACATATGAAGGTAAGCCAGTAGCTGACAATCAAGAGTTTATCGTCGCTACAAATAACTATCGTGGAAGTAGCCAAACG
TTCCCAGGTGTAAGTAAAGGGGAAGTTGTATACCAATCACAAGATGAAACACGTCAAATCATTGTGAAGTATATGCAAGA
AACACCAGTTATTGATCCGGCAGCAGATAAAAATTGGGCATTTAAACCGATTGTTGCAGATAAATTAAATACAACATTTG
ATTCTTCACCGAATGCACAAAAGTATATAAAGAAAGATGGGAACATATCGTATGTTGGACCATCTGAAAATGAATTCGCT
AAATATGCAATTGATATAACGAAGAAGAACGATGATGATAAGGAAACTGGTGGAGAGAACCCGACAATACCGCCAACCGG
TGAAGGAGATAATGGAGAGAACCCGACAACACCGCCAACTGGTGAAGGAAATAATGGAGAGAACCCGACGACACCACCAA
CAGGTGAAGGAAACAATGGAGGAAATCCAACCACACCATCAACAGATGAAGGTAATAATGCTGGATCTGGACAAACTACA
ACGGATAATCAAAACTCAAAAGAAACAACAACTGTAAGTGAGAACAAAGAAGAACGTGATTTACCGAAAACAGGTACAAA
TGTTGCGTCTACAATTGGAGCAGGTTTGGCGTTTATCGGAGCTGGATTCCTTCTGTTATTTAGAAGAAAGAAAGCAAATA
GATAA

Upstream 100 bases:

>100_bases
ATAGAAGAAAAAAGGTATGTGGTTAGAGACTGATAGAAATTCATTTCATTATTCTTTGGTAATTGTATAAGGGGGATTTT
TTGTGAAAAAGTCAAAAAAA

Downstream 100 bases:

>100_bases
TCGAGAAATATAAAAAGGATTACCTTAATCGGTAATCCTTTTTCGTATATTATGAAATTGTTACTGCCTTTTCTTTCTTC
CATGAAAGGCCAAATCCAGT

Product: bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV
LFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYK
DDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAEGAD
VIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVNGKWEVQ
KEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLF
AENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAGQFNQID
PKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNYRGSSQT
FPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFA
KYAIDITKKNDDDKETGGENPTIPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNAGSGQTT
TDNQNSKETTTVSENKEERDLPKTGTNVASTIGAGLAFIGAGFLLLFRRKKANR

Sequences:

>Translated_774_residues
MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV
LFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYK
DDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAEGAD
VIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVNGKWEVQ
KEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLF
AENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAGQFNQID
PKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNYRGSSQT
FPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFA
KYAIDITKKNDDDKETGGENPTIPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNAGSGQTT
TDNQNSKETTTVSENKEERDLPKTGTNVASTIGAGLAFIGAGFLLLFRRKKANR
>Mature_774_residues
MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV
LFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYK
DDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAEGAD
VIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVNGKWEVQ
KEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLF
AENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAGQFNQID
PKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNYRGSSQT
FPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFA
KYAIDITKKNDDDKETGGENPTIPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNAGSGQTT
TDNQNSKETTTVSENKEERDLPKTGTNVASTIGAGLAFIGAGFLLLFRRKKANR

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1790658, Length=645, Percent_Identity=46.2015503875969, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1786687, Length=235, Percent_Identity=25.1063829787234, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573524, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922444, Length=298, Percent_Identity=25.503355704698, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 84797; Mature: 84797

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKV
CCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEECCEEECCCCCCE
GLVQTATLVNKAREEAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLM
EEEHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHH
NLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYKDDKDNNEENDQNYFKPYHVF
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHCCHHHHH
EKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAEGAD
HHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
VIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFG
EEEEEECCCCCCCCCEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHCCCCEEECCCCC
SNLGIIDMQLKKVNGKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDY
CCCCEEEEEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLFAENGQYSKYKGIPVLSAGAP
HHHHCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCEEEECCCC
FKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAGQFNQID
CCCCCCCCCEEEEECCCCCEECCCCEEEEEECCEEEEEEECHHHHHHHHHHCCCCCCCCC
PKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKP
CCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCC
VADNQEFIVATNNYRGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWA
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
FKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFAKYAIDITKKNDDDKETGGEN
CCCCHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCHHCCCCC
PTIPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNAGSGQTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TDNQNSKETTTVSENKEERDLPKTGTNVASTIGAGLAFIGAGFLLLFRRKKANR
CCCCCCCCCEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKV
CCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEECCEEECCCCCCE
GLVQTATLVNKAREEAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLM
EEEHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHH
NLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYKDDKDNNEENDQNYFKPYHVF
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHCCHHHHH
EKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAEGAD
HHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
VIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFG
EEEEEECCCCCCCCCEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHCCCCEEECCCCC
SNLGIIDMQLKKVNGKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDY
CCCCEEEEEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLFAENGQYSKYKGIPVLSAGAP
HHHHCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCEEEECCCC
FKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAGQFNQID
CCCCCCCCCEEEEECCCCCEECCCCEEEEEECCEEEEEEECHHHHHHHHHHCCCCCCCCC
PKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKP
CCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCC
VADNQEFIVATNNYRGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWA
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
FKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFAKYAIDITKKNDDDKETGGEN
CCCCHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCHHCCCCC
PTIPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNAGSGQTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TDNQNSKETTTVSENKEERDLPKTGTNVASTIGAGLAFIGAGFLLLFRRKKANR
CCCCCCCCCEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]