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The map label for this gene is infB [H]

Identifier: 30263816

GI number: 30263816

Start: 3624802

End: 3626862

Strand: Reverse

Name: infB [H]

Synonym: BA_3950

Alternate gene names: 30263816

Gene position: 3626862-3624802 (Counterclockwise)

Preceding gene: 30263817

Following gene: 30263815

Centisome position: 69.38

GC content: 37.99

Gene sequence:

>2061_bases
ATGAGTAAAATTCGAGTGCATGAATATGCGAAAAAACATAATATCTCAAGTAAAGATCTTATGACAAAACTAAAAGAAAT
GAATATCGAGGTTTCGAATCATATGACAATGTTAGACGATGAAGTAGTAAACAAATTAGATAATGAGTATCAAGCTGAAA
AACCTTCTGTTGCAGATGAGTTTGAAGTAGAAGAAAAAGTTGTTCGTAGTAAAAAGAACAGCAATAAGAAAAAGAAAAAA
GGCAAAGGAAACGAAGACAAGCGTCAAGAGAACTTTGCTGGAAGACAACAAACACAAACTGTAGAAACACCAGATAAAAT
TACTTTCTCTGGAAGCCTTACAGTAGGTGACCTTGCTAAGAAATTAAGCAAAGAGCCATCTGAAATTATTAAAAAGCTCT
TCATGCTTGGAATTATGGCAACAATTAACCAAGACTTAGATAAAGATACAATTGAGTTAATTGCTAACGACTACGGTATT
GAAGTAGAAGAAGAAGTAATTGTTAGCGAGACTGAGTTTGAAACATTCATCGATGAGCAAGATGATGAAGAGAACTTAAA
AGAGCGTCCAGCTGTAGTTACAATCATGGGACACGTTGACCATGGTAAAACAACATTACTTGACTCTATCCGTAACTCTA
AAGTAACTGCTGGCGAAGCAGGTGGAATTACTCAGCATATCGGTGCATACCAAGTTGAATTAAATGACAAGAAGATTACA
TTCTTAGACACACCTGGTCACGCGGCGTTTACAACTATGCGTGCTCGTGGTGCACAAGTAACGGATATTACAATCATTGT
TGTTGCAGCTGATGACGGCGTAATGCCACAAACAGTTGAAGCGATTAACCATGCGAAAGCAGCAGGAGTACCAATTATTG
TTGCTGTGAATAAAATGGATAAACCAGCAGCAAATCCTGATCGCGTAATGCAAGAATTAACAGAATATGAATTAGTTCCA
GAAGCATGGGGCGGAGACACAATTTTCGTACCAATTTCTGCAATTCAAGGCGAAGGAATTGACAACTTACTAGAAATGAT
TCTTCTTATAAGTGAAGTAGAAGAATATAAAGCAAATCCAAACCGCTATGCAACTGGTACTGTAATTGAAGCACAGCTTG
ATAAAGGTAAAGGAACTATCGCGACATTACTTGTTCAAAACGGTACGCTTCGAGTTGGAGACCCAATCGTTGTTGGTACT
TCATTCGGACGTGTTCGTGCAATGGTAAGTGATATTGGTCGCCGTGTAAAAGTTGCTGGTCCATCAACTCCTGTTGAAAT
TACAGGTTTAAACGAAGTACCACAAGCGGGAGATCGTTTCATGGCATTCGCTGATGAGAAGAAAGCTCGTCAAATCGGTG
AATCACGTGCGCAAGAAGCGTTACTTGCTCAACGTGGTGAAAAATCTAAATTAAGCCTTGAAGATTTATTCCAACAAATC
CAAGAGGGCGATGTAAAAGAAATTAACTTAATTGTGAAAGCAGACGTACAAGGTTCTGTAGAAGCAATGGCAGCATCACT
TCGTAAAATTGATGTTGAAGGTGTTAAAGTTAAAATTATCCATACAGGCGTAGGTGCGATTACAGAATCTGATATCATTT
TAGCTTCTGCATCTAATGCAATTGTAATTGGATTTAACGTACGCCCAGATGTGAATGCGAAGCGTACAGCTGAATTAGAG
AACGTTGATATTCGTTTACACCGTATTATTTATAAAGTAATCGAAGAGATCGAAGCAGCGATGCAAGGTATGTTAGATCC
AGAATTCGAAGAAAAAGTAATCGGTCAAGCAGAAGTACGTCAAACGTTTAAAGTAACAAAAGTTGGAACAATCGCAGGTT
GTTACGTAACAGACGGTAAAATTACACGTGATAGTGGCGTGCGTATTATCCGTGATGGCGTAGTAATTTTCGAAGGACAA
CTTGATACGTTAAAACGTTTCAAAGACGACGTAAAAGAAGTTGCACAAAACTATGAGTGTGGTATTACAATTGAGAGATA
TAATGATCTTAAAGAAGGGGACATTATTGAAGCATACATTATGGAAGAAGTGAAGCGATGA

Upstream 100 bases:

>100_bases
GCGATTGGGAGAGATGAGCGAGTCGTTGTAGCTGTGTTAGATGAAGGCTTTGCGAAAAAGCTGCGTAGCATGCTCGATAC
AAATTACCGGGGGTGAAGGT

Downstream 100 bases:

>100_bases
TAATCGCTTCACTCTCATTCGAGTGTATGATTTACGATGTGCATTCTTTAAAAGAGAAACGAGCAATTTTGCAACGGGTG
CTAACTCGTGTGAAACAGCG

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKK
GKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVELNDKKIT
FLDTPGHAAFTTMRARGAQVTDITIIVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVP
EAWGGDTIFVPISAIQGEGIDNLLEMILLISEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
SFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELE
NVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQ
LDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR

Sequences:

>Translated_686_residues
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKK
GKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVELNDKKIT
FLDTPGHAAFTTMRARGAQVTDITIIVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVP
EAWGGDTIFVPISAIQGEGIDNLLEMILLISEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
SFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELE
NVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQ
LDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
>Mature_685_residues
SKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKG
KGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIE
VEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVELNDKKITF
LDTPGHAAFTTMRARGAQVTDITIIVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPE
AWGGDTIFVPISAIQGEGIDNLLEMILLISEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTS
FGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQIQ
EGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELEN
VDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQL
DTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR

Specific function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 7

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI53729339, Length=651, Percent_Identity=36.2519201228879, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI53729337, Length=651, Percent_Identity=36.2519201228879, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI84043963, Length=463, Percent_Identity=26.3498920086393, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI157426893, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI34147630, Length=260, Percent_Identity=31.1538461538462, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789559, Length=579, Percent_Identity=54.5768566493955, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI2367247, Length=213, Percent_Identity=31.4553990610329, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1788922, Length=233, Percent_Identity=29.1845493562232, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994988, Length=137, Percent_Identity=35.7664233576642, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790412, Length=234, Percent_Identity=32.4786324786325, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789737, Length=234, Percent_Identity=32.4786324786325, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=539, Percent_Identity=37.291280148423, Blast_Score=328, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI212656558, Length=568, Percent_Identity=27.112676056338, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17557151, Length=219, Percent_Identity=30.5936073059361, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556456, Length=268, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25141371, Length=257, Percent_Identity=29.1828793774319, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324550, Length=614, Percent_Identity=36.8078175895765, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319282, Length=531, Percent_Identity=26.9303201506591, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324761, Length=258, Percent_Identity=31.3953488372093, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28572034, Length=653, Percent_Identity=36.7534456355283, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24656849, Length=456, Percent_Identity=27.1929824561404, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI160714833, Length=122, Percent_Identity=54.9180327868852, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI78706572, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363316, Length=263, Percent_Identity=30.4182509505703, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864358, Length=263, Percent_Identity=30.4182509505703, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921738, Length=248, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137380, Length=272, Percent_Identity=28.3088235294118, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922690, Length=230, Percent_Identity=27.3913043478261, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006847
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000178
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; PF04760 IF2_N [H]

EC number: NA

Molecular weight: Translated: 75753; Mature: 75622

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
CCCCCHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHHHHHHHHCHHHCCCCCCCCHH
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAK
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHH
KLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEECHHHHHHCCCC
DDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVELNDKKIT
CCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCEEE
FLDTPGHAAFTTMRARGAQVTDITIIVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
EEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLISEVEEYKANP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCC
NRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAG
CCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEECCHHHHHHHHHHHCCEEEECC
PSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
CCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
HCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEEEECCCCEECCCEEEEECCCE
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHH
QTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYEC
HHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCC
GITIERYNDLKEGDIIEAYIMEEVKR
CEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
CCCCHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHHHHHHHHCHHHCCCCCCCCHH
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAK
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHH
KLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEECHHHHHHCCCC
DDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVELNDKKIT
CCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCEEE
FLDTPGHAAFTTMRARGAQVTDITIIVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
EEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLISEVEEYKANP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCC
NRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAG
CCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEECCHHHHHHHHHHHCCEEEECC
PSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
CCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
HCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEEEECCCCEECCCEEEEECCCE
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHH
QTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYEC
HHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCC
GITIERYNDLKEGDIIEAYIMEEVKR
CEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA