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The map label for this gene is fruR [H]

Identifier: 30263722

GI number: 30263722

Start: 3521890

End: 3522642

Strand: Reverse

Name: fruR [H]

Synonym: BA_3848

Alternate gene names: 30263722

Gene position: 3522642-3521890 (Counterclockwise)

Preceding gene: 30263723

Following gene: 30263721

Centisome position: 67.39

GC content: 35.33

Gene sequence:

>753_bases
ATGTTAACTCCTGAACGTCATCAAATGATATTGCAACTTGTAAAAGAGCAGAAGGTTGTTAAATTACAGCAATTAGTGGA
AAGAACAGCGAGCTCTGAATCAACAATTCGTCGTGATTTAGCGCAATTGGAAAAACAACGGTTATTAAAAAGAGTTCACG
GTGGTGCGGCTGTTTTAACAGGAAAAGGACAGGAGCCGACGATGGTTGAAAAATCATCCAAAAACATTCAGATAAAACAA
CAAATTGCGAAGTATGCGGCTAGCGTTGTGGAACAAGGTGATTTCATTTATTTAGATGCAGGAAGTACAACATTTGAAAT
GATTCCATTTTTAATAAATAAAGATGTTACTGTCGTTACGAATGGACTTATGCATATTGAAGCTTTAGTTGAAAATAATA
TTCGTGCCTATTTACTAGGCGGAATGATGAAGAGTAGGACGAAAGCTTTAATCGGTGCTATGGCACAGGAAAGTATGCAG
AAGTATCGTTTTGATAAATGTTTTTTAGGAGCGAATGGTGTACATGAACAGCTTGGTTTTACAACACCAGATCCGGAAGA
GGCGCTTTTAAAGCAAATGGCATTAACATTAGCAAATGAAGGATATTTCTTAATTGATGAAAGTAAGTTTTCGGAAGTTG
CGTTTGCGAAAATTGCCAATGTTGAAGAGGCAAATATTATTACAAACCATTTAGAAATTGATTTAGAAAAATATAAAAGA
CAAACCAATGTAATTGAGGCTGATAAACAATGA

Upstream 100 bases:

>100_bases
TTATAACTGTTCGTGATTGTTTTTTGGTTATTTGTGAATGTTTATGGTTGATTTTTGTGATCGTTTTCATTATACTGTAA
TCAAAGAAGAGGTGAATAAA

Downstream 100 bases:

>100_bases
TCTATACAGTAACTTTAAACCCATCTATTGATTATGTAGTACAAGTTAATTCCTTAGATTTAGGCGCAGTAAATCGAGCG
GAGAAAGATATGAAGTTTCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDFIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ

Sequences:

>Translated_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDFIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ
>Mature_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDFIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=32.5991189427313, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=31.4814814814815, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789059, Length=233, Percent_Identity=30.4721030042918, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789829, Length=219, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=29.7413793103448, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787063, Length=228, Percent_Identity=28.5087719298246, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790635, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082344, Length=249, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790753, Length=214, Percent_Identity=23.3644859813084, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=26.0683760683761, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28117; Mature: 28117

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVVEQGDFIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC
>Mature Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVVEQGDFIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]