Click here to switch to the map view.

The map label for this gene is nprM [H]

Identifier: 30263348

GI number: 30263348

Start: 3163554

End: 3165251

Strand: Reverse

Name: nprM [H]

Synonym: BA_3442

Alternate gene names: 30263348

Gene position: 3165251-3163554 (Counterclockwise)

Preceding gene: 30263349

Following gene: 30263347

Centisome position: 60.55

GC content: 34.28

Gene sequence:

>1698_bases
ATGAATAATTTCGTAAAGTTAGGTTTAACTACAGGAGTGGTGTTATCGGCGATTATTCCTTATGGAGGAGTACATGCGGC
AACAGAAGATTTAAAAGTGGAAACAAAGGAAGATACGTTCCGAACAGGTAATTTAACAGCACCTTCTCAAAAATCGGCAG
AAAATGTAGTAAAGGATGCGCTGAAAGGGAAAACAGAACAAGCATTATCCTCAAAGCAAGTTAACACGGAATCAAAAGTT
AATTATAATGTGACGCAAAGTCGTAAATCTTATGATGGTACTACATTGGTGCGTCTTCAACAAACATATGAAGGACGTGA
TGTATACGGATATCAACTAACAGCACATATTAATGATGATGGTGTACTTACGAGTATTTCGGGGGATAGTGCCCAAGATC
TACAACAACAGGAAGATTTGAAACAACCTATTATTCTATCAGAAGAGGATGCAAAGAAGCAGCTTTTTAAAATCTATGGG
GATAATCTCACATTTGTTGAAGAACCAGAAATTAAACAAGTGGTATATGTAGATGAAAATACAAATAAAGCTACAAACGC
ATATCAAATTACTTTTAGTGCCTCTACACCTGAATATGTATCTGGTACGGTATTAATTGATGCTTTTGTTGGGGATCTAT
TAAAAGAACTCGTTCAAAAATTGGGTATACAAGTAGATAGCAGTATCGTTCAATCTGCAACAGCAAATAAATCACAAGAT
CCTTCAAAATTAACAGGAACAGGAAAAGATGATTTAGGTATGAATCGTACGTTTGGAATTACACAGCGAAGTGATGGAAC
GTACACTCTTGCAGATTATTCTCGTGGTAAGGGAATTGAAACGTATACTGCGAATTATAAAGATTATAATAATTATAGAA
GAAATGTATGGGGGTATTTGGATGATTTAGTAACAAGTAATTCTACAAATTTTACAGATCCTAAAGCAGTTAGTGCACAT
TATTTAGCAACGAAAGTATATGATTTTTATAAAGAAAAATATAGTCGTAACAGCTTTGATAATAATGGACAAAAAGTAAT
TTCAGTTGTTCATGGCTGGAATACAAATGGTAAGAATATAGGGAATCCTAAGCAGTGGTTTAATGCATTTAGTAATGGGG
CTATGCTAGTATACGGAGATCCAATTGTTAGAGCATTTGATGTGGCAGGACATGAGTTTACACACGCGGTTACAAGAAAT
GAGTCTGGACTTGAGTACGCAGGAGAAGCTGGTGCCATTAATGAGGCTCTATCTGATATTTTAGGGGTAGCAGTTGAAAA
GTATGCCAATAACGGAAAGTTCAATTGGACAATGGGGGAACAATCAGGTCGTATATTTAGAGATATGAAAAACCCATCAT
CTATCTCTTCTAGATATCCAGAAGATTATAGACATTATAATAATTTACCTATTGATGCTGACCATGATTATGGTGGTGTA
CACACGAACTCTAGCATTATAAATAAAGTAGCTTATTTAATTGCTAGTGGTGGAAATCATAATGGAGTAAATGTACAAGG
TATTGGGGAAGATAAAATGTTTGATATTTTCTATTATGCAAATACCGATGAATTAAATATGACTTCTGATTTTAAAGAAT
TAAAAGAAGCTTGTATTCGTGTAGCAATGAATTTATATGGTAAAGACTCATTAGAAGTACAAGCTGTTCAACAAGCATTT
AAAGCAGCTTATATTTAA

Upstream 100 bases:

>100_bases
TATGTAAAATTGATTGACTATAGTTAAAAGTTTTATCTATGCTTAAAATTCTAAAGTACATTTATTTAATTTAATAATAA
GATTACAAAGGAGTAAGAAT

Downstream 100 bases:

>100_bases
TACTATTGTGATGAATTATAAACCCTTTCATTTTAATATAATGATTAATATGTATGTATACACAAAAACCTTGTAGAATT
TTTCTGCAAGGTTTTTTAGA

Product: neutral protease

Products: NA

Alternate protein names: Neutral protease [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MNNFVKLGLTTGVVLSAIIPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPIILSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLTGTGKDDLGMNRTFGITQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYKEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVAMNLYGKDSLEVQAVQQAF
KAAYI

Sequences:

>Translated_565_residues
MNNFVKLGLTTGVVLSAIIPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPIILSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLTGTGKDDLGMNRTFGITQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYKEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVAMNLYGKDSLEVQAVQQAF
KAAYI
>Mature_565_residues
MNNFVKLGLTTGVVLSAIIPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPIILSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLTGTGKDDLGMNRTFGITQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYKEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVAMNLYGKDSLEVQAVQQAF
KAAYI

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.28 [H]

Molecular weight: Translated: 62635; Mature: 62635

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFVKLGLTTGVVLSAIIPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSISGDSAQDLQQQEDLKQPIILSEEDAKKQLFKIYGDNLTFVEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
CCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PSKLTGTGKDDLGMNRTFGITQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CCCCCCCCCCCCCCCCEECEEECCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYKEKYSRNSFDNNGQKVISVVHGWNTNGKNI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCE
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
ECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VAMNLYGKDSLEVQAVQQAFKAAYI
HHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNFVKLGLTTGVVLSAIIPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSISGDSAQDLQQQEDLKQPIILSEEDAKKQLFKIYGDNLTFVEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
CCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PSKLTGTGKDDLGMNRTFGITQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CCCCCCCCCCCCCCCCEECEEECCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYKEKYSRNSFDNNGQKVISVVHGWNTNGKNI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCE
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
ECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VAMNLYGKDSLEVQAVQQAFKAAYI
HHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7764969 [H]