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The map label for this gene is zwf [H]

Identifier: 30263341

GI number: 30263341

Start: 3157927

End: 3158475

Strand: Reverse

Name: zwf [H]

Synonym: BA_3434

Alternate gene names: 30263341

Gene position: 3158475-3157927 (Counterclockwise)

Preceding gene: 30263342

Following gene: 270000545

Centisome position: 60.42

GC content: 32.97

Gene sequence:

>549_bases
ATGGATTCAATGACATTTCTTTTATTTGGAGCGACAGGGGATTTAGCGAAACGCAAAATTTACCCTGCTTTATACAAATT
ATTTAGTAATGGGAATATACCGCAATCTATTTCGATTATCGGTATTGGTAGAAGGGTAATGTCAGATGTGGAATTTCAAA
CAAAGGTAGAACAATCCCTTGCTACATTTTCTAGAAGATCTACTGATGACGAATCAGGAGTAGAAGAATTTCTTAGCACA
TTTCGTTATTGTCAATTAAATACAGCGAATATAGAGGACTATCAAGATTTGTTGAGTCTTGTAAAGAGACGTGAAACAGA
ATTAAACATTCCTGAAAACCGTATGTTTTACCTATCTGTTATACCAAAAGTATTTGATGTCATTGCTTTAAATATTAAGG
AAAGTGGATTGTGGGCTACAAAAGGATTGAACCGTCTTATTATAGAGAAGCCTTTTGGTCATCATGTAACGTCTGCTCAC
GAGTTTAACGAAAAATTAATTGAAGATTTTGATGAAACTGATATTTTTTATATCGATCATTATCTTTGA

Upstream 100 bases:

>100_bases
AACATTGGTAAAGTATGAGGTTTTAGAGACAGTATTGTGCTAAGTAGCGAATGAGTTTATATATTCTATTCTAGCAATTG
TTTTAAAAGGGAGAGAACAA

Downstream 100 bases:

>100_bases
AAATGAGTGGTAACTAAGGATAAACTTAGAAAAGTATTACGAAATAAATAGTATGTAATTTAAGACATTTTTATTGACGA
TAATAATTTATGTGGTTAAT

Product: glucose-6-phosphate dehydrogenase domain-containing protein

Products: NA

Alternate protein names: G6PD; Vegetative protein 11; VEG11 [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNIPQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDESGVEEFLST
FRYCQLNTANIEDYQDLLSLVKRRETELNIPENRMFYLSVIPKVFDVIALNIKESGLWATKGLNRLIIEKPFGHHVTSAH
EFNEKLIEDFDETDIFYIDHYL

Sequences:

>Translated_182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNIPQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDESGVEEFLST
FRYCQLNTANIEDYQDLLSLVKRRETELNIPENRMFYLSVIPKVFDVIALNIKESGLWATKGLNRLIIEKPFGHHVTSAH
EFNEKLIEDFDETDIFYIDHYL
>Mature_182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNIPQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDESGVEEFLST
FRYCQLNTANIEDYQDLLSLVKRRETELNIPENRMFYLSVIPKVFDVIALNIKESGLWATKGLNRLIIEKPFGHHVTSAH
EFNEKLIEDFDETDIFYIDHYL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=181, Percent_Identity=32.5966850828729, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI108773793, Length=181, Percent_Identity=32.5966850828729, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI52145310, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1788158, Length=180, Percent_Identity=30, Blast_Score=93, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17538218, Length=179, Percent_Identity=35.195530726257, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324088, Length=177, Percent_Identity=36.7231638418079, Blast_Score=110, Evalue=9e-26,
Organism=Drosophila melanogaster, GI221513548, Length=182, Percent_Identity=32.967032967033, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643350, Length=178, Percent_Identity=30.8988764044944, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643352, Length=178, Percent_Identity=30.8988764044944, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 21017; Mature: 21017

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNIPQSISIIGIGRRVMSDVEFQTKVEQSL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHH
ATFSRRSTDDESGVEEFLSTFRYCQLNTANIEDYQDLLSLVKRRETELNIPENRMFYLSV
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
IPKVFDVIALNIKESGLWATKGLNRLIIEKPFGHHVTSAHEFNEKLIEDFDETDIFYIDH
HHHHHHHHHHCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
YL
CC
>Mature Secondary Structure
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNIPQSISIIGIGRRVMSDVEFQTKVEQSL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHH
ATFSRRSTDDESGVEEFLSTFRYCQLNTANIEDYQDLLSLVKRRETELNIPENRMFYLSV
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
IPKVFDVIALNIKESGLWATKGLNRLIIEKPFGHHVTSAHEFNEKLIEDFDETDIFYIDH
HHHHHHHHHHCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
YL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9298659 [H]