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The map label for this gene is yjcD [H]

Identifier: 30261334

GI number: 30261334

Start: 1194405

End: 1196378

Strand: Reverse

Name: yjcD [H]

Synonym: BA_1239

Alternate gene names: 30261334

Gene position: 1196378-1194405 (Counterclockwise)

Preceding gene: 30261335

Following gene: 30261333

Centisome position: 22.89

GC content: 35.16

Gene sequence:

>1974_bases
ATGGAAGAAGATGCAGATGCGGCGTATTTCCGCGCTCTCGAACAGCAAAATGTATTTTTAAACGAAAAACAATTAGAAGC
CGTACGAACGACAGAAGGTCCTGTTCTTACATTGGCTGGTGCCGGAAGTGGAAAAACATCTGTTTTAACAACTCGCGTAG
GTTATTTAGTAAATGTAAAACAAGTTCATCCGCGAAATATTTTATTACTTACATTTACACAAAAAGCGGCTGAAGAAATC
CGAAATCGCGTAGCGAATTTACCGGGTATGAATCATGCGGCAAGTAGCTATGTTGTTGCCGGTACGTTTCACTCTGTCTT
TTTAAAATTGCTTCGTAGTCAAGGATATAATCAGCAAATTTTAGCAAACGAAAAACATAAACAAATTATGATAAAGAAAA
TTTTAAAAGAATTGCGTTTAAAAGACGCTTATGATGCTGAAACGATGCTCGCGATGATTTCACTTGAGAAAAACAAGTTG
AATCGCCCGAAAGATGTAAAAGCAAAAACACCTGTTGAACAAGAATTTAAAGAAGTATACGAGCGTTTTGAAGAAGTGAA
ACAACGATATAACTATATCGATTTCGATGACATCTTATTAGAAACATATTATATGTTAGAAAATAATGCTCCTTTGCTTA
CCCAATTACAACAACGTTTTCACTATATTGAAGTAGATGAGTTCCAAGATACATCGTATGCACAATATGAAATTGTAAAA
TTGTTAGCTTCGCCAAGAAATAATTTGTTTATCGCAGGTGATGACGATCAGGCAATATATGGCTGGCGAGGAGCAAGTCA
CCAAATTATTTTATCTTTCCCAAAAGAATTTGATAACACTACGATTATTGCCCTTAATACGAATTATCGATCCAATCCTT
TTATTGTCGGACTTGGAAATGAAGTTATCAAACTAAATCAAGAGCGTTTTGATAAAGAGCTATATTCTGTACGCGAAGAA
GGTGTACAACCTTTTTACGCAAGGCCGGCTACGACTCTTGATGAAGCAAACCAAATTTTGCAGCTCATTCAAGAAAAGGT
AGATAGCGGTGAACGAAACTATAAAGATTTTTGTTTACTATATCGCACACATTCTGTAAGCCGTTCGTTACTTGATCAGC
TTACCATTCATAAAATCCCGTTCATTAAGCACGGCGCAAGTCAGTCATTTTATGAACATTCTTTAATTAAGCCTGTATTA
GACCATTTACGACTCGTAATTGAGCCGTTTCGATTAGAATCACTTTCAAATATATTACCAACGATGTATATCGGGCGTGA
TGATTGTATTTCATTTATTGAACGTGAACAATGGAAATATGGTGAAGGTCGTTTTCCTTCTCTTCTTCATTTCTTATTAT
TAAATCCAAGCTTAAAACCTTTTCAAGTGAAAAAGGTAAATGAGCGTATCGATTTTATTAAATTTATAAAAGAATTAGAA
CCGAAAAAAGCTTTAAAAGAAATTATTCATGGTAAAGGAAAGTATTTAGAGTACTTACAAAGTAACGATCGTTCTTCCTT
TACGATGCATAAAGATATACAAGAAGAAATGTTAGAAGAATTAATGGAGTCGGCAAATCGTTTCACCGACATTCCAGCTT
ATTTACAATTTATTGATGAAGCCATTCAAGGGCAAAAAGAAATGGAAGCATTAAAAACAATGCCGCAAAAAGATGCTGTT
TCGCTTATGTCTATTCATAACGCAAAAGGTCTTGAATTTCCATGCGTCTTTTTACTTGGAGCGAGCGATGGTATTCTGCC
CCACACTTCTTCTTTAAAAGATGCTAACGACCGTGTTACAGAGACTTCTGAAGCTTTAGAAGAAGAACGCCGACTACTTT
ATGTCGCAATTACACGGGCGAAAGAAGAACTTTACATTTCCTCTCCGCAATTTTTTAGAGGAAAAAAATTAGATATATCT
CGTTTTTTATACACTGTGCGAAAAGATTTACCTGAAAAGACATCCACTAAATAA

Upstream 100 bases:

>100_bases
TGAATGTATGACACAAGAAAAATTTTCACAAAAATCATTAACGCACGCTGATATTCCACGTGCAACATATCATATTCCGA
AAACATCTACCCATTTAATT

Downstream 100 bases:

>100_bases
GGATGTCTTTTTTTATATTGTATTATGTACATCCCTACTATATAAATTCCCTGCTTTTATCGTAAGAATTAACGTAATAT
CAACCATATCCCGTTCATAT

Product: ATP-dependent DNA helicase UvrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MEEDADAAYFRALEQQNVFLNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEI
RNRVANLPGMNHAASSYVVAGTFHSVFLKLLRSQGYNQQILANEKHKQIMIKKILKELRLKDAYDAETMLAMISLEKNKL
NRPKDVKAKTPVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVK
LLASPRNNLFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREE
GVQPFYARPATTLDEANQILQLIQEKVDSGERNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGASQSFYEHSLIKPVL
DHLRLVIEPFRLESLSNILPTMYIGRDDCISFIEREQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKELE
PKKALKEIIHGKGKYLEYLQSNDRSSFTMHKDIQEEMLEELMESANRFTDIPAYLQFIDEAIQGQKEMEALKTMPQKDAV
SLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRVTETSEALEEERRLLYVAITRAKEELYISSPQFFRGKKLDIS
RFLYTVRKDLPEKTSTK

Sequences:

>Translated_657_residues
MEEDADAAYFRALEQQNVFLNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEI
RNRVANLPGMNHAASSYVVAGTFHSVFLKLLRSQGYNQQILANEKHKQIMIKKILKELRLKDAYDAETMLAMISLEKNKL
NRPKDVKAKTPVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVK
LLASPRNNLFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREE
GVQPFYARPATTLDEANQILQLIQEKVDSGERNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGASQSFYEHSLIKPVL
DHLRLVIEPFRLESLSNILPTMYIGRDDCISFIEREQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKELE
PKKALKEIIHGKGKYLEYLQSNDRSSFTMHKDIQEEMLEELMESANRFTDIPAYLQFIDEAIQGQKEMEALKTMPQKDAV
SLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRVTETSEALEEERRLLYVAITRAKEELYISSPQFFRGKKLDIS
RFLYTVRKDLPEKTSTK
>Mature_657_residues
MEEDADAAYFRALEQQNVFLNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEI
RNRVANLPGMNHAASSYVVAGTFHSVFLKLLRSQGYNQQILANEKHKQIMIKKILKELRLKDAYDAETMLAMISLEKNKL
NRPKDVKAKTPVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVK
LLASPRNNLFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREE
GVQPFYARPATTLDEANQILQLIQEKVDSGERNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGASQSFYEHSLIKPVL
DHLRLVIEPFRLESLSNILPTMYIGRDDCISFIEREQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKELE
PKKALKEIIHGKGKYLEYLQSNDRSSFTMHKDIQEEMLEELMESANRFTDIPAYLQFIDEAIQGQKEMEALKTMPQKDAV
SLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRVTETSEALEEERRLLYVAITRAKEELYISSPQFFRGKKLDIS
RFLYTVRKDLPEKTSTK

Specific function: May be involved in the generation of recombinogenic substrates for the subsequent action of recA [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=675, Percent_Identity=31.5555555555556, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI48994965, Length=651, Percent_Identity=29.1858678955453, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1787196, Length=359, Percent_Identity=27.5766016713092, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322369, Length=410, Percent_Identity=27.8048780487805, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324477, Length=419, Percent_Identity=22.9116945107399, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76064; Mature: 76064

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEDADAAYFRALEQQNVFLNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVK
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHEEHHHHEEEEE
QVHPRNILLLTFTQKAAEEIRNRVANLPGMNHAASSYVVAGTFHSVFLKLLRSQGYNQQI
EECCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCHH
LANEKHKQIMIKKILKELRLKDAYDAETMLAMISLEKNKLNRPKDVKAKTPVEQEFKEVY
HCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHH
LLASPRNNLFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGN
HHHCCCCCEEEECCCCCEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCC
EVIKLNQERFDKELYSVREEGVQPFYARPATTLDEANQILQLIQEKVDSGERNYKDFCLL
HHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEH
YRTHSVSRSLLDQLTIHKIPFIKHGASQSFYEHSLIKPVLDHLRLVIEPFRLESLSNILP
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMYIGRDDCISFIEREQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKELE
HHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PKKALKEIIHGKGKYLEYLQSNDRSSFTMHKDIQEEMLEELMESANRFTDIPAYLQFIDE
HHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AIQGQKEMEALKTMPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRVT
HHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
ETSEALEEERRLLYVAITRAKEELYISSPQFFRGKKLDISRFLYTVRKDLPEKTSTK
HHHHHHHHHHHEEEEEEECCHHHHEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEEDADAAYFRALEQQNVFLNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVK
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHEEHHHHEEEEE
QVHPRNILLLTFTQKAAEEIRNRVANLPGMNHAASSYVVAGTFHSVFLKLLRSQGYNQQI
EECCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCHH
LANEKHKQIMIKKILKELRLKDAYDAETMLAMISLEKNKLNRPKDVKAKTPVEQEFKEVY
HCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHH
LLASPRNNLFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGN
HHHCCCCCEEEECCCCCEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCC
EVIKLNQERFDKELYSVREEGVQPFYARPATTLDEANQILQLIQEKVDSGERNYKDFCLL
HHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEH
YRTHSVSRSLLDQLTIHKIPFIKHGASQSFYEHSLIKPVLDHLRLVIEPFRLESLSNILP
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMYIGRDDCISFIEREQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKELE
HHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PKKALKEIIHGKGKYLEYLQSNDRSSFTMHKDIQEEMLEELMESANRFTDIPAYLQFIDE
HHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AIQGQKEMEALKTMPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRVT
HHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
ETSEALEEERRLLYVAITRAKEELYISSPQFFRGKKLDISRFLYTVRKDLPEKTSTK
HHHHHHHHHHHEEEEEEECCHHHHEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]