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The map label for this gene is citM [H]

Identifier: 77748720

GI number: 77748720

Start: 4118340

End: 4119668

Strand: Direct

Name: citM [H]

Synonym: XAC3485

Alternate gene names: 77748720

Gene position: 4118340-4119668 (Clockwise)

Preceding gene: 21244209

Following gene: 21244211

Centisome position: 79.57

GC content: 63.43

Gene sequence:

>1329_bases
ATGCTGACCGCGCTCGGTTTCGGAATGGTGATCACCTTCATGTACCTGATCATGAGCAAGCGGCTATCGCCGTTGGTGGC
TTTGATCACGGTACCGATCGTGTTCGCGTTGCTGGGCGGCTTCGGCACCGGCATCAACGAGATGATGCTCGAAGGCATCA
AGAAGATCGCGCCCACCGGCGTGATGCTGATGTTCGCCATCCTGTATTTCGGGGTGATGATCGATGCCGGGCTGTTCGAC
CCGCTGGTCGGCCGCATCCTGCGCCTGGTCAAGGGCGACCCGCTGAAGATCGTGATGGGCACGGCGATCCTGGCGATGCT
GATCTCGCTCGACGGCGACGGCTCCACCACCTACATGATCACCGTCTCGGCCATGTTGCCGCTGTACCAGCGCCTGGGCA
TGAACGCGCTCAACCTCACCTGCGTCACCATCCTTGCCAGCGGCGTGATGAACCTGACTCCGTGGGGCGGCCCCACCGCG
CGTGCGGCCACCGCGCTGCATGTGGAACCGGGCGATGTGTTCGTGCCGCTGGTGCCGGCCATGCTGCTGGCGATCGCCGG
CATCCTTGCGCTGGCGTGGTATCTGGGCATGCGCGAACGCCGCCGCCTGGGCGTGGTGCGCCTGCCGGCGGACGGCAACT
GGCTGGACACCAGCATCCCCGAAGACAACGACGCCCTGCCGCGCGTGGAAGACACCGAGGACATGAAGCGGCCCAAGCTG
CTGTGGGTGAATCTGCTGTTGACGTTGGTCTTGATGGGCGCGCTGGTGAAGGGCGTGCTGCCGATGCCGGTGCTGTTCAT
GATCGGCTTCGCGCTGGCGCTGATGATCAACTACCCCAATCTGGCCGAACAGCGCCGCCGCCTGGTCAACCACGCCGGCA
ACGTGCTGTCGGTGGTGTCGCTGATTTTCGCTGCCGGCATCTTCACCGGCATCCTGTCCAACACCGGCATGGTCGAAGCG
ATGTCGCGCAGTTCTCTGGCCGTCATTCCCGATAGCTGGGGTCCGTACCTGGCGGTGATCACCGCCATCGTCAGCATGCC
GTTTACGTTCTTCATGTCCAACGACGCGTTCTATTTCGGCGTGCTGCCGATCCTGTCGGAAGCCGCAGGCCATTACGGCA
TCACCCCGGTGGAAATGGCCCGCGCTTCGCTCGCCGGCCAGCCGGTGCACCTGCTCAGCCCCCTGGTGCCATCGACCTAT
CTTTTGGTCGGGTTGGCCAAGGTCGACTTCGCCGACCATCAACGCTTCACGCTCAAGTGGGCGGTGTTGATTTCGCTGTT
GATGCTGGGCGGCGGGTTGTTGTTTGGTCTCTTTCCACTCGCGCGTTGA

Upstream 100 bases:

>100_bases
GTCCAGCAGCAACCGCGCACCTGCATCGTCGGCGCTGCGCACCTTGCGCAACGCTGAGCTCCACTCTCCCCCTGCTGTAC
GCCTCAAAGGATTCGCCCGC

Downstream 100 bases:

>100_bases
CTGCCGCCGGGAATGGGGAATCGGGAGTGGGGAATCGGTAGGGCGGCGCTATGCAGTCGTTTCGATTCCTGACGTCCAAA
TACGAAAACAGATACCGAAA

Product: Mg++/citrate complex transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLTALGFGMVITFMYLIMSKRLSPLVALITVPIVFALLGGFGTGINEMMLEGIKKIAPTGVMLMFAILYFGVMIDAGLFD
PLVGRILRLVKGDPLKIVMGTAILAMLISLDGDGSTTYMITVSAMLPLYQRLGMNALNLTCVTILASGVMNLTPWGGPTA
RAATALHVEPGDVFVPLVPAMLLAIAGILALAWYLGMRERRRLGVVRLPADGNWLDTSIPEDNDALPRVEDTEDMKRPKL
LWVNLLLTLVLMGALVKGVLPMPVLFMIGFALALMINYPNLAEQRRRLVNHAGNVLSVVSLIFAAGIFTGILSNTGMVEA
MSRSSLAVIPDSWGPYLAVITAIVSMPFTFFMSNDAFYFGVLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTY
LLVGLAKVDFADHQRFTLKWAVLISLLMLGGGLLFGLFPLAR

Sequences:

>Translated_442_residues
MLTALGFGMVITFMYLIMSKRLSPLVALITVPIVFALLGGFGTGINEMMLEGIKKIAPTGVMLMFAILYFGVMIDAGLFD
PLVGRILRLVKGDPLKIVMGTAILAMLISLDGDGSTTYMITVSAMLPLYQRLGMNALNLTCVTILASGVMNLTPWGGPTA
RAATALHVEPGDVFVPLVPAMLLAIAGILALAWYLGMRERRRLGVVRLPADGNWLDTSIPEDNDALPRVEDTEDMKRPKL
LWVNLLLTLVLMGALVKGVLPMPVLFMIGFALALMINYPNLAEQRRRLVNHAGNVLSVVSLIFAAGIFTGILSNTGMVEA
MSRSSLAVIPDSWGPYLAVITAIVSMPFTFFMSNDAFYFGVLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTY
LLVGLAKVDFADHQRFTLKWAVLISLLMLGGGLLFGLFPLAR
>Mature_442_residues
MLTALGFGMVITFMYLIMSKRLSPLVALITVPIVFALLGGFGTGINEMMLEGIKKIAPTGVMLMFAILYFGVMIDAGLFD
PLVGRILRLVKGDPLKIVMGTAILAMLISLDGDGSTTYMITVSAMLPLYQRLGMNALNLTCVTILASGVMNLTPWGGPTA
RAATALHVEPGDVFVPLVPAMLLAIAGILALAWYLGMRERRRLGVVRLPADGNWLDTSIPEDNDALPRVEDTEDMKRPKL
LWVNLLLTLVLMGALVKGVLPMPVLFMIGFALALMINYPNLAEQRRRLVNHAGNVLSVVSLIFAAGIFTGILSNTGMVEA
MSRSSLAVIPDSWGPYLAVITAIVSMPFTFFMSNDAFYFGVLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTY
LLVGLAKVDFADHQRFTLKWAVLISLLMLGGGLLFGLFPLAR

Specific function: Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibited by the presence of magnesium ions [H]

COG id: COG2851

COG function: function code C; H+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014738
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 47622; Mature: 47622

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTALGFGMVITFMYLIMSKRLSPLVALITVPIVFALLGGFGTGINEMMLEGIKKIAPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
VMLMFAILYFGVMIDAGLFDPLVGRILRLVKGDPLKIVMGTAILAMLISLDGDGSTTYMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
TVSAMLPLYQRLGMNALNLTCVTILASGVMNLTPWGGPTARAATALHVEPGDVFVPLVPA
EHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHH
MLLAIAGILALAWYLGMRERRRLGVVRLPADGNWLDTSIPEDNDALPRVEDTEDMKRPKL
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHH
LWVNLLLTLVLMGALVKGVLPMPVLFMIGFALALMINYPNLAEQRRRLVNHAGNVLSVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHH
LIFAAGIFTGILSNTGMVEAMSRSSLAVIPDSWGPYLAVITAIVSMPFTFFMSNDAFYFG
HHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCHHEEECCCCHHHH
VLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTYLLVGLAKVDFADHQRFTLKW
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHH
AVLISLLMLGGGLLFGLFPLAR
HHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MLTALGFGMVITFMYLIMSKRLSPLVALITVPIVFALLGGFGTGINEMMLEGIKKIAPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
VMLMFAILYFGVMIDAGLFDPLVGRILRLVKGDPLKIVMGTAILAMLISLDGDGSTTYMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
TVSAMLPLYQRLGMNALNLTCVTILASGVMNLTPWGGPTARAATALHVEPGDVFVPLVPA
EHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHH
MLLAIAGILALAWYLGMRERRRLGVVRLPADGNWLDTSIPEDNDALPRVEDTEDMKRPKL
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHH
LWVNLLLTLVLMGALVKGVLPMPVLFMIGFALALMINYPNLAEQRRRLVNHAGNVLSVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHH
LIFAAGIFTGILSNTGMVEAMSRSSLAVIPDSWGPYLAVITAIVSMPFTFFMSNDAFYFG
HHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCHHEEECCCCHHHH
VLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTYLLVGLAKVDFADHQRFTLKW
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHH
AVLISLLMLGGGLLFGLFPLAR
HHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 7704256; 8892821 [H]