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The map label for this gene is appC [H]

Identifier: 77748686

GI number: 77748686

Start: 3485256

End: 3486656

Strand: Reverse

Name: appC [H]

Synonym: XAC2983

Alternate gene names: 77748686

Gene position: 3486656-3485256 (Counterclockwise)

Preceding gene: 21243711

Following gene: 21243709

Centisome position: 67.37

GC content: 62.31

Gene sequence:

>1401_bases
ATGGACGCACTGCTGTTATCGCGGATCCAGTTTGGATTCGTCATCGCGTTCCACGTATTGTTTCCGGCATTCACCATCGG
GCTTTCCAGTCTGCTGGCGTTTCTGGAATGGCGCTGGTTGCGCACGCGTCTGCCGGTCTGGCGCGAGCTGTATTTTTTCT
GGCAGAAGATCTTTGCCGTGTCCTTCGGCATGGGCGTGGTCAGCGGCATCGTGATGGCCTTCCAGTTCGGGGCCAACTGG
CCGGAATTGAGCCGCGTGGCCGGTGGCGTGATCGGGCCACTGCTGAGCTATGAAGTGCTCACCGCGTTCTTTCTGGAAGC
CAGTTTCCTGGGCGTGATGATGTTCGGCTGGGGGCGTATTTCCGAGCGCCTGCATTTCCTGTCCACCTGCATGGTGGCGC
TGGGCACGCTGTTTTCCACGTTCTGGATTCTTTCGTCCAATAGCTGGTTGCAGACCCCGGCCGGCTTTGATGTCATCGGC
GGCATCGTGCATCCGGTCGACTGGTTGAAGATCATCTTCAATCCCTCGTTCCCGTACCGGCTTGCGCACATGGCGCTTGG
CTCATTCATCACCACCTGCTTCGTGGTGGGTGCAGTGGGCGCGTGGTATCTGCATCGTGGCGTGCATCGCCAAGCCGGGC
TGTGCATGCTGAAGCTGGCCGTGGTGTTTGCCGCGATCGCCGTACCGCTGCAGATCGTTGTCGGCGACATGCACGGCTTG
AACACGCTCAAGCATCAGCCGATGAAGATCGCCGCGATGGAAGCGCACTGGCATGACGAAAAACAGGGCGAGGGATTCCC
GCTGGTGGTGTTTGCGGTGCCCAACGCACAGGCCGAGCGTAACGACTATGAGGTGGCGATTCCGCGCCTGGGCAGCCTGA
TTCTGACCCACCGCCCGGATGGCAGCATCGCACCGCTGACGTCGGTGCCGGCAAGCGAGCGCCCGTCGGTGACGCCGGTG
TTCTTCGCCTTCCGCATCATGGTAGGGATTGGCTCATTGATGCTGCTGGTGGCCTGGGTGTCTGCGTTCGCGTTGTGGCG
CGGCAAGCTGGTGCACTGGCGCTGGTTGCTGGCGGTTTGGCGCTGGATGTTGCCGAGCGGCTTCATCGCGCTGATTTCCG
GCTGGTTCGTCACCGAAATCGGCCGGCAGCCCTATGCGGTCTACGGCTTGTTGCGCACCGCCGATGCGGTGGGCCCGCAG
TCTGCGCTGATGACGGCCATCTCGCTGGCGGTGTATGTAGCCGGCTACGCGTTCGTGTTCGGCTGGGGCATCTGGTACCT
GGTCAAGATCGGCAAGCAAGGGCCCACCCCACATGCCGACGCGCCGCATCTGGACCATGGCGAACACACGCCCGCACGGC
CGCTGTCGGCAGCCGACGAATCGATCGACGGAGCCGCATGA

Upstream 100 bases:

>100_bases
GCCTAGCGCAGCAGCGTGCGCGCGATCGCCCGATGCAGTGCATCCCGGTGATCGACCTGCGAGCTGCACGTCGACGATCA
TTTTTCCTGGAGGGTTCTCC

Downstream 100 bases:

>100_bases
TGGAGATGACGAGCGTCTTGCCGGTGGCGTGGTTTGCGGTGATCGGCTTCGGGGTGCTGATGTACGTCGTGCTGGACGGG
TTCGTGCTCGGCATCGGCAT

Product: quinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit I [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLSTCMVALGTLFSTFWILSSNSWLQTPAGFDVIG
GIVHPVDWLKIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLCMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHDEKQGEGFPLVVFAVPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPSVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVHWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYAVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADESIDGAA

Sequences:

>Translated_466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLSTCMVALGTLFSTFWILSSNSWLQTPAGFDVIG
GIVHPVDWLKIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLCMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHDEKQGEGFPLVVFAVPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPSVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVHWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYAVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADESIDGAA
>Mature_466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLSTCMVALGTLFSTFWILSSNSWLQTPAGFDVIG
GIVHPVDWLKIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLCMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHDEKQGEGFPLVVFAVPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPSVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVHWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYAVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADESIDGAA

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=512, Percent_Identity=31.0546875, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87081779, Length=334, Percent_Identity=30.2395209580838, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 51560; Mature: 51560

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]