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The map label for this gene is pcbC [H]

Identifier: 77748669

GI number: 77748669

Start: 3172557

End: 3173495

Strand: Reverse

Name: pcbC [H]

Synonym: XAC2713

Alternate gene names: 77748669

Gene position: 3173495-3172557 (Counterclockwise)

Preceding gene: 21243441

Following gene: 21243439

Centisome position: 61.32

GC content: 63.79

Gene sequence:

>939_bases
ATGAGCGCGCGCATCCCCACGCTGGACATCACCCGTTTCGACACCGATCGCGAGGCCTTCGTCGCCGAGCTCGGAGCGGC
TTATCGGCAGTGGGGCTTTGCCGGCATCCGCAATCACGGCATCGCCCAGGCCGACATCGACGCCGCCTACGAAGTGTTCA
AGGCGTTCTTCGCGCTGCCGGAAGCGACCAAGCGCCGTTATCACGTGGAAGGCAGCGGCGGCGCGCGCGGCTACACCGCG
TTCGGCGTGGAAACCGCCAAGGATTCCAAGCACTTCGATCTCAAGGAGTTCTGGCACATCGGCCGCGAGATTCCGGACGA
TTCGCCGTACCGCGCAGTGATGCCGCCGAACCTGTGGCCCAGCGAAGTGGCTGGTTTCCGCGAGCGCGGCCACCAGCTGT
ACCAGCAACTGGATCAACTGGGTTCGCGCGTGCTGTCGGCGCTGGCGCTGCATATCGGCCTGCCGCAGGACTACTTCGTC
GACAAGACCAACAACGGCAATTCGATCCTGCGGCCGATCCATTACCCGCCGATCACCAGCGACGACATCCCCAACGTGCG
TGCCGGCGCGCATGGCGACATCAATTTCATCACCTTGCTGGTGGGTGCCAGTGCCGCCGGCCTGGAAGTGCGTTCCCACG
AGGGCGAGTGGGTGCCGTTCACGGCCGACGCCGACACCATCGTGGTCAACATCGGCGACATGCTGCAGCGCCTGACCAAC
CATGTATATCCGTCCACCATCCACCGCGTGGTCAATCCACCGGGAGAGCAGGCGCGCCAACCGCGCTATTCGGTGCCGTT
CTTCCTGCACCCCAATCCGGATTTCCTCATCGACGTGCTGCCTTCGTGCATCAGCGCGGACAATCCCAGCCGTTATCCGG
AGCCGATCACGGCCCATGGCTTCCTGGAAGAGCGTCTGCGCGAGATCAAGCTGAAGTAA

Upstream 100 bases:

>100_bases
TGGTCATCGCCAAGGCCGCGACGTTTTACCTGTTGTATCGCCTGCTGATCTGACCCGCAGGTTTCTCTCGACCCTTTCGA
CCTTGACTGCAGACATCCGT

Downstream 100 bases:

>100_bases
TCCGGCGTGTCGGGACGCGTTGCGCGGCGCCAATAGCCGCGCCCGCAACACGACCGGTGACCGGCGCCGCACTTTTGTTC
AGAAAATTCCGCACGCGCCT

Product: oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSARIPTLDITRFDTDREAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYEVFKAFFALPEATKRRYHVEGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVAGFRERGHQLYQQLDQLGSRVLSALALHIGLPQDYFV
DKTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHEGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Sequences:

>Translated_312_residues
MSARIPTLDITRFDTDREAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYEVFKAFFALPEATKRRYHVEGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVAGFRERGHQLYQQLDQLGSRVLSALALHIGLPQDYFV
DKTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHEGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK
>Mature_311_residues
SARIPTLDITRFDTDREAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYEVFKAFFALPEATKRRYHVEGSGGARGYTAF
GVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVAGFRERGHQLYQQLDQLGSRVLSALALHIGLPQDYFVD
KTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHEGEWVPFTADADTIVVNIGDMLQRLTNH
VYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=273, Percent_Identity=30.03663003663, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI85816264, Length=287, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34909; Mature: 34777

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARIPTLDITRFDTDREAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYEVFKAFFALP
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
EATKRRYHVEGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWP
HHHCCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCH
SEVAGFRERGHQLYQQLDQLGSRVLSALALHIGLPQDYFVDKTNNGNSILRPIHYPPITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEECCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSHEGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC
>Mature Secondary Structure 
SARIPTLDITRFDTDREAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYEVFKAFFALP
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
EATKRRYHVEGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWP
HHHCCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCH
SEVAGFRERGHQLYQQLDQLGSRVLSALALHIGLPQDYFVDKTNNGNSILRPIHYPPITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEECCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSHEGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]