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The map label for this gene is pkn1 [H]

Identifier: 77748654

GI number: 77748654

Start: 2811366

End: 2812982

Strand: Reverse

Name: pkn1 [H]

Synonym: XAC2412

Alternate gene names: 77748654

Gene position: 2812982-2811366 (Counterclockwise)

Preceding gene: 21243148

Following gene: 21243145

Centisome position: 54.35

GC content: 69.82

Gene sequence:

>1617_bases
TTGCGGGAAGACCGCCTGTATCGCGATGCCGGCGATGCGATCCCCTTGTATCTGGCGATCCAGCAGCGCGCCGGTGGCAA
GGATGCGGCCAGCCGTCGCGGCCTGGAGCAGGCGCGTGGCCGGTTGCTTGAACGCGGCGCGGCGCTGATCGAACAAACCG
AGCGCCAGGACGACGCGTTGGAGCAGGCGCGTGAAGTGGCCTTCGTGGCGCTCGCCCTTGCCCCACAGGACCCGAAGGTG
CGCGCACTGCAGCGCGAGGTGGAAACCGCGCAGCGCGTGCTTGCGTTCAACCGCGCCGGCGAGGAAGACCTGCGCGGCGG
GCGGCTGGGCGAGGACGGCAATGGCGCGCTGGTGAATTTTCGCGATGCCGCACAACTGGATCCCGACAATCCGCGCACCC
GGCAGGGCCTGGCCGCCGTGGAAAGCGGCCTGTTGGAGCGCGCCGAACAGGCGGCACAGGCAAGCGACTTCATCGGTGCC
CGTTATTGGCTGCAGATGGCCGGGCAGGTACGCGACCGTGCGCCCACCATCGCCGATGCGCGCGCGCGGGTCGAACGCGT
GCGCCGGGCGCAGATCGCTGGGTTGCACGACGCCGGTCTGCACGATCTCACCTCGCCGCGCGGGCTCAAGGCGGCCGGCC
AAAAGCTTGCCGAAGTGCTGCGCATCGCCGACCCCGGAGATCCGGTGGCCGGCGATCTGCGCCGCCGGCTGGAGCTGGCC
ACGCATTACGGCAGCTTCCGTCCCGGCCAGGTATTCACCGACGGGCTCAAGGTCGGCGGGCGCGGGCCGCAGATGATCGT
GGTGCCGCATGGCGCATTCCAGATGGGAGCTGGTGATGCCGAGCCGGGCGCATCCGACAACGAGCGCCCCGCCCATTACG
TGCGCTTCGCACGCGGCTTTGCGTTGTCGATCACCGAGGTCACGGTTGCCGAGTTCCGCCAGTTCGTCGAAGCCACCGGC
GCGCGCCCGCGTGCCACCCGGCGCGGGCATTCGGTGGTCTACGACGAGCGCAGCGGCAACTTCATCCGTCGCAGCGGTGT
GGATTGGCAGTCCGACTACAACGGCGCCCAGGCCGCGCCCAACAGCCCGGTGATGCACGTGAGCATTCGCGACGCCGAAG
CGTATGCGTCCTGGCTGTCGGAACAGACCGGCCGCCATTACCACGTGCCCAGCGAGGCCGAGTTCGAGTATGCGGTGCGT
GCCGGCACCACCGGACGTTACCCGTGGGGCAACGCAGGCTCGCCGCCGGCCGACGCCGGCAATTTCACCGGCGGCAACGA
CGTCTCGCGTAGCGGCCGGCACTGGAACAACGGCTTCGTCGGCTACGGCGATGGCTTTTGGGGCCCGGCGCCGGTCGGCA
GTTTTCGCGCCAACGCGTGGGGTCTGCACGACATGGGCGGCAACCTGAGCGAATGGGTGGCCGACTGCTGGCACGCCAGC
TACCGCCGTGCACCGGCCGATGGCGCTGCCTGGTACAACCCGGGCTGCCGGCAACGCATGATCCGCGGCGGCAGCTGGGC
CAATTCGCCGCAACAGACGCGCGCGGCCTGGCGGCAGTCGCAGGACTCGGACACCACCAGTGCCCGTATCGGCTTTCGCG
TCGCACGCGGAATCTAG

Upstream 100 bases:

>100_bases
TGGCGAAGAATCCGCCGAAACCGTGGCGCAATGGCAACCGCCGGCGGTGGAGTTGGGCGACGAGCCCCCGGCACAGGTGC
GCAAACGCGCGGACCAGGCA

Downstream 100 bases:

>100_bases
CGACGACCGGCAGCGGATGGGCGCGTCGATCGCGTCCTGCGCGACTGCCGCCTTCTGCTTGCCGTCGCTGTCGCCGCGAA
CGCTTTCGGATCGGCCCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARGRLLERGAALIEQTERQDDALEQAREVAFVALALAPQDPKV
RALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESGLLERAEQAAQASDFIGA
RYWLQMAGQVRDRAPTIADARARVERVRRAQIAGLHDAGLHDLTSPRGLKAAGQKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVEATG
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVR
AGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARGI

Sequences:

>Translated_538_residues
MREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARGRLLERGAALIEQTERQDDALEQAREVAFVALALAPQDPKV
RALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESGLLERAEQAAQASDFIGA
RYWLQMAGQVRDRAPTIADARARVERVRRAQIAGLHDAGLHDLTSPRGLKAAGQKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVEATG
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVR
AGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARGI
>Mature_538_residues
MREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARGRLLERGAALIEQTERQDDALEQAREVAFVALALAPQDPKV
RALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESGLLERAEQAAQASDFIGA
RYWLQMAGQVRDRAPTIADARARVERVRRAQIAGLHDAGLHDLTSPRGLKAAGQKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVEATG
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVR
AGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARGI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=299, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI257470977, Length=295, Percent_Identity=30.1694915254237, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI257470975, Length=285, Percent_Identity=29.8245614035088, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI194248087, Length=294, Percent_Identity=30.6122448979592, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194248088, Length=309, Percent_Identity=30.42071197411, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI226437577, Length=183, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194248090, Length=225, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130397, Length=303, Percent_Identity=29.3729372937294, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 58675; Mature: 58675

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARGRLLERGAALIEQTERQDDAL
CCCCCCHHCCCCCCEEEEEEEHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALVNF
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEEE
RDAAQLDPDNPRTRQGLAAVESGLLERAEQAAQASDFIGARYWLQMAGQVRDRAPTIADA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RARVERVRRAQIAGLHDAGLHDLTSPRGLKAAGQKLAEVLRIADPGDPVAGDLRRRLELA
HHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFARGF
HHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHCCC
ALSITEVTVAEFRQFVEATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAP
EEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPADAG
CCCEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
NFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHAS
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHH
YRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARGI
HCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEHHCCC
>Mature Secondary Structure
MREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARGRLLERGAALIEQTERQDDAL
CCCCCCHHCCCCCCEEEEEEEHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALVNF
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEEE
RDAAQLDPDNPRTRQGLAAVESGLLERAEQAAQASDFIGARYWLQMAGQVRDRAPTIADA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RARVERVRRAQIAGLHDAGLHDLTSPRGLKAAGQKLAEVLRIADPGDPVAGDLRRRLELA
HHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFARGF
HHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHCCC
ALSITEVTVAEFRQFVEATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAP
EEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPADAG
CCCEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
NFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHAS
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHH
YRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARGI
HCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]