Click here to switch to the map view.

The map label for this gene is aprX [H]

Identifier: 77748591

GI number: 77748591

Start: 1746205

End: 1748652

Strand: Direct

Name: aprX [H]

Synonym: XAC1512

Alternate gene names: 77748591

Gene position: 1746205-1748652 (Clockwise)

Preceding gene: 21242259

Following gene: 21242265

Centisome position: 33.74

GC content: 65.52

Gene sequence:

>2448_bases
ATGGCGACAAGCAAGCCCCCACGTTCGAAACCTGCACGCGCGCTACCGCGCAAGGCTGCTGCAAGCACGCAACAACCGGC
GCGGCCGCGCACTGCGCGTGCGCAGCAGGCCGGGGCCCAGGAGTCCGCGGCGACCCGCGTGCAGGGCAAGGCGCGCACGG
TGATCTACATCCATGGCATCGGCAACAAGCCGCCGGCTGATGTGCTGCGTTGTCAGTGGGACAAGGCCTTGTTCGGGCGG
CCCATGGGCGAGCGTACGCGGCTGGCGTACTGGGTCAATCGCGAGCGCTATCCAGTGGCCGAGCCGGGCAATTGCGATGC
GCGCGATGTGGGTCCGGCGCTCAATCAAAGCGTGCAGCGTGCCTTGAGCACGCTTGGCCTGGTGCCGGGCGAACAGGACC
TGCACCTGTTGGCAGACGCGCTGGCGCAGAGCGAGCAGGAACGTGCCGATCTGCATCGGCTGCTGGACGAGCTTCAGGGC
GCGTCCGTGCGCGGCAGCGTGCAGGCCAAGGGGGCCATCGATGCGATCAACCGGGTGTTGCTGCGGCTGATTTCCGCTGC
ATTGTTGCAGGACGTGCATGACCTGTTCTTCGTGCCGGAACGTGCGGCGCTGATGCGCGAAAGTCTGGCGCAGCGGCTGC
GTGCAGGCGGCGGGCCATTCGTGGTGGTGGCGCACAGCCAGGGTTCGATGATCGCCTTCGATGTGCTGCGCCAGCTGAAG
GCTGCCGACTGCGAGGTCAGTTTGTTCCTCACCCTGGGCTCGCCACTGGGGTTGCCGCAGGTGCGGAGCATGTTCAAGCG
CTGGACCGGCACGCGCAAACTGCCGTTCCCCGGGTGCGTACAGCGCTGGATCAATGTGACCGAAACGCGCGACCCGATCG
CGCTGGACCCGGACCTCACCGACGACATCGCCAATGCAAAAGGACGTTTCGAAAACCTGGCCGCTGCGCGCTTGAATCCG
GACTGGCAGCACAACCCGCATTCGGCTTCGGGCTATCTGTCGATTCCGCAGGTGCGCGCCGCGGTGCGCCAAGCCGTGGG
TGTGGGCTTCGATCAGCCGGTGTCCAATGCAGTGCTGATCAAGGACCTCAGCGAGCAGCTCGAAGCGCATGGCCCGGAGC
ACCGACACGATGTGCTGATCGAGCTGGATCGGCGCGTGTTGGGTAACGACCCTGCCGGTGCGCGCGCATTGCTGTTGCAG
CATGTGCGCCAAGCCGCTGCGCGCACCACCGGCTTGAGTGGTGATGCGCTGGATGAGGCGATCGAGCTGGAAGACAGCCT
GCAGCGTTTCGTGTCTGCGCGGCTCACCCGATTCGAGATCGAATCGCTGCAGGATCGCTATCGCACATTGGGCTTTCGGC
GGGTGTGGCGCAATGCCGGAAAACGCGCGTTGATCCATGTGTCGGGCAATGTCCTGCATGCCGATGCGGCACGCACGGCG
TATCGCGCGCGCGGGCAGCAGATCGGTTGGGCGGTGATGGATACCGGCATCGCGGCCGGTCACCCGCATTTTTTCCTCAA
GGGTGAGCGCGACAACGTGGTGGCACAGTGGGATTGCACGCGGCGCGGTGCGCCCAAACGGCTGACCCGCGCCGACGGCA
CTGCGTTTACCCGGCTCGATCGGCATGGGCACGGCACGCATATCGCCGGCATCATCGCCGGGCAGTGTCGCGCTTCGATC
CCGGATGCGAGCGGCACGCCCGGCCGTACGCTTGAATTTTCCGGCATGGCGCCGGATACGCAGCTGTATGGCTTCAAGGT
ACTCGACGATGCCGGAAACGGCCGCGACTCGTGGACGATCAAGGCGGTGCAGCAGGTGGCCGACATCAACGAGCGCGCCG
GCGAGCTGGTCATCCATGGCGTCAATCTGAGCCTAGGCGGCTGCTTCGACCCGGAGAGCTACGGCTGTGGGTTTACGCCG
TTGTGCAATGAATTACGCCGGCTGTGGCGGCAAGGCGTGCTGGTGGTGATCGCTGCCGGCAACGAGGGCCTGGCCTGGTT
GATGCGCAACGATGGCGATGCGTATGCGGCCAACATGGATCTGTCGATCAGCGACCCGGGCAACCTGGAAGACGCCATCG
TGGTCGGCTCGGTGCACAAGAGCAGCCCACACAACTATGGCGTGTCGTATTTTTCCTCGCGCGGGCCGACTGCCGACGGC
CGCAGCAAGCCGGATGTGGTCGCGCCAGGGGAGAAGATCCTGTCGGCCTACTACGACTTCGACCCAGGCGACCCGGCCGG
CCTGATGGTGGAGATGAGCGGCACCAGCATGGCCGCACCGCATGTCTCCGGCGTGCTGGCGGGTTTCCTATCGGCGCGCC
GCGAGTTCATCGGCTTCCCCGATCGGGTTAAGCAACTGCTGCTGGATACCTGTACCGACCTGCAGCGCGACCGCTATGTG
CAGGGCAGGGGAGTGCCGAATGTGATGCGGATGCTTGGAGCGACGTGA

Upstream 100 bases:

>100_bases
GGGATCGGCGCGCCCTGTCACAAGTGGTGAGATGCGCAACGCTTACAGTGGCTTCAGTCCCGTACCGAACGGAACAGTCT
GCAAACGAAGGAGCGAAGCG

Downstream 100 bases:

>100_bases
TTCGGGAAGCGGCAGTGGGGAGTCGGGAATCGTAAAAGCGACCAGCATCCACGACCTCAGCTCGTGCTCAGCCGGCTATA
TCGCTGCCGCTGCGGGAAAG

Product: serine peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MATSKPPRSKPARALPRKAAASTQQPARPRTARAQQAGAQESAATRVQGKARTVIYIHGIGNKPPADVLRCQWDKALFGR
PMGERTRLAYWVNRERYPVAEPGNCDARDVGPALNQSVQRALSTLGLVPGEQDLHLLADALAQSEQERADLHRLLDELQG
ASVRGSVQAKGAIDAINRVLLRLISAALLQDVHDLFFVPERAALMRESLAQRLRAGGGPFVVVAHSQGSMIAFDVLRQLK
AADCEVSLFLTLGSPLGLPQVRSMFKRWTGTRKLPFPGCVQRWINVTETRDPIALDPDLTDDIANAKGRFENLAAARLNP
DWQHNPHSASGYLSIPQVRAAVRQAVGVGFDQPVSNAVLIKDLSEQLEAHGPEHRHDVLIELDRRVLGNDPAGARALLLQ
HVRQAAARTTGLSGDALDEAIELEDSLQRFVSARLTRFEIESLQDRYRTLGFRRVWRNAGKRALIHVSGNVLHADAARTA
YRARGQQIGWAVMDTGIAAGHPHFFLKGERDNVVAQWDCTRRGAPKRLTRADGTAFTRLDRHGHGTHIAGIIAGQCRASI
PDASGTPGRTLEFSGMAPDTQLYGFKVLDDAGNGRDSWTIKAVQQVADINERAGELVIHGVNLSLGGCFDPESYGCGFTP
LCNELRRLWRQGVLVVIAAGNEGLAWLMRNDGDAYAANMDLSISDPGNLEDAIVVGSVHKSSPHNYGVSYFSSRGPTADG
RSKPDVVAPGEKILSAYYDFDPGDPAGLMVEMSGTSMAAPHVSGVLAGFLSARREFIGFPDRVKQLLLDTCTDLQRDRYV
QGRGVPNVMRMLGAT

Sequences:

>Translated_815_residues
MATSKPPRSKPARALPRKAAASTQQPARPRTARAQQAGAQESAATRVQGKARTVIYIHGIGNKPPADVLRCQWDKALFGR
PMGERTRLAYWVNRERYPVAEPGNCDARDVGPALNQSVQRALSTLGLVPGEQDLHLLADALAQSEQERADLHRLLDELQG
ASVRGSVQAKGAIDAINRVLLRLISAALLQDVHDLFFVPERAALMRESLAQRLRAGGGPFVVVAHSQGSMIAFDVLRQLK
AADCEVSLFLTLGSPLGLPQVRSMFKRWTGTRKLPFPGCVQRWINVTETRDPIALDPDLTDDIANAKGRFENLAAARLNP
DWQHNPHSASGYLSIPQVRAAVRQAVGVGFDQPVSNAVLIKDLSEQLEAHGPEHRHDVLIELDRRVLGNDPAGARALLLQ
HVRQAAARTTGLSGDALDEAIELEDSLQRFVSARLTRFEIESLQDRYRTLGFRRVWRNAGKRALIHVSGNVLHADAARTA
YRARGQQIGWAVMDTGIAAGHPHFFLKGERDNVVAQWDCTRRGAPKRLTRADGTAFTRLDRHGHGTHIAGIIAGQCRASI
PDASGTPGRTLEFSGMAPDTQLYGFKVLDDAGNGRDSWTIKAVQQVADINERAGELVIHGVNLSLGGCFDPESYGCGFTP
LCNELRRLWRQGVLVVIAAGNEGLAWLMRNDGDAYAANMDLSISDPGNLEDAIVVGSVHKSSPHNYGVSYFSSRGPTADG
RSKPDVVAPGEKILSAYYDFDPGDPAGLMVEMSGTSMAAPHVSGVLAGFLSARREFIGFPDRVKQLLLDTCTDLQRDRYV
QGRGVPNVMRMLGAT
>Mature_814_residues
ATSKPPRSKPARALPRKAAASTQQPARPRTARAQQAGAQESAATRVQGKARTVIYIHGIGNKPPADVLRCQWDKALFGRP
MGERTRLAYWVNRERYPVAEPGNCDARDVGPALNQSVQRALSTLGLVPGEQDLHLLADALAQSEQERADLHRLLDELQGA
SVRGSVQAKGAIDAINRVLLRLISAALLQDVHDLFFVPERAALMRESLAQRLRAGGGPFVVVAHSQGSMIAFDVLRQLKA
ADCEVSLFLTLGSPLGLPQVRSMFKRWTGTRKLPFPGCVQRWINVTETRDPIALDPDLTDDIANAKGRFENLAAARLNPD
WQHNPHSASGYLSIPQVRAAVRQAVGVGFDQPVSNAVLIKDLSEQLEAHGPEHRHDVLIELDRRVLGNDPAGARALLLQH
VRQAAARTTGLSGDALDEAIELEDSLQRFVSARLTRFEIESLQDRYRTLGFRRVWRNAGKRALIHVSGNVLHADAARTAY
RARGQQIGWAVMDTGIAAGHPHFFLKGERDNVVAQWDCTRRGAPKRLTRADGTAFTRLDRHGHGTHIAGIIAGQCRASIP
DASGTPGRTLEFSGMAPDTQLYGFKVLDDAGNGRDSWTIKAVQQVADINERAGELVIHGVNLSLGGCFDPESYGCGFTPL
CNELRRLWRQGVLVVIAAGNEGLAWLMRNDGDAYAANMDLSISDPGNLEDAIVVGSVHKSSPHNYGVSYFSSRGPTADGR
SKPDVVAPGEKILSAYYDFDPGDPAGLMVEMSGTSMAAPHVSGVLAGFLSARREFIGFPDRVKQLLLDTCTDLQRDRYVQ
GRGVPNVMRMLGAT

Specific function: Displays serine protease activity. Seems to have a broad substrate specificity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=335, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320775, Length=323, Percent_Identity=27.8637770897833, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324576, Length=399, Percent_Identity=26.8170426065163, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550681, Length=352, Percent_Identity=26.7045454545455, Blast_Score=84, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 88659; Mature: 88527

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSKPPRSKPARALPRKAAASTQQPARPRTARAQQAGAQESAATRVQGKARTVIYIHGI
CCCCCCCCCCCHHHCCHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCEEEEEEEEC
GNKPPADVLRCQWDKALFGRPMGERTRLAYWVNRERYPVAEPGNCDARDVGPALNQSVQR
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHH
ALSTLGLVPGEQDLHLLADALAQSEQERADLHRLLDELQGASVRGSVQAKGAIDAINRVL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LRLISAALLQDVHDLFFVPERAALMRESLAQRLRAGGGPFVVVAHSQGSMIAFDVLRQLK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
AADCEVSLFLTLGSPLGLPQVRSMFKRWTGTRKLPFPGCVQRWINVTETRDPIALDPDLT
HCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCHHCCCCCEEECCCCC
DDIANAKGRFENLAAARLNPDWQHNPHSASGYLSIPQVRAAVRQAVGVGFDQPVSNAVLI
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCCCHHHH
KDLSEQLEAHGPEHRHDVLIELDRRVLGNDPAGARALLLQHVRQAAARTTGLSGDALDEA
HHHHHHHHHCCCCCHHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IELEDSLQRFVSARLTRFEIESLQDRYRTLGFRRVWRNAGKRALIHVSGNVLHADAARTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECHHHHHH
YRARGQQIGWAVMDTGIAAGHPHFFLKGERDNVVAQWDCTRRGAPKRLTRADGTAFTRLD
HHHCCCCCCHHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHH
RHGHGTHIAGIIAGQCRASIPDASGTPGRTLEFSGMAPDTQLYGFKVLDDAGNGRDSWTI
CCCCCCEEEEEEECCHHCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCCHHHH
KAVQQVADINERAGELVIHGVNLSLGGCFDPESYGCGFTPLCNELRRLWRQGVLVVIAAG
HHHHHHHHHHHCCCEEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEC
NEGLAWLMRNDGDAYAANMDLSISDPGNLEDAIVVGSVHKSSPHNYGVSYFSSRGPTADG
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCC
RSKPDVVAPGEKILSAYYDFDPGDPAGLMVEMSGTSMAAPHVSGVLAGFLSARREFIGFP
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCH
DRVKQLLLDTCTDLQRDRYVQGRGVPNVMRMLGAT
HHHHHHHHHHHHHHHHHCEECCCCCHHHHHHHCCC
>Mature Secondary Structure 
ATSKPPRSKPARALPRKAAASTQQPARPRTARAQQAGAQESAATRVQGKARTVIYIHGI
CCCCCCCCCCHHHCCHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCEEEEEEEEC
GNKPPADVLRCQWDKALFGRPMGERTRLAYWVNRERYPVAEPGNCDARDVGPALNQSVQR
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHH
ALSTLGLVPGEQDLHLLADALAQSEQERADLHRLLDELQGASVRGSVQAKGAIDAINRVL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LRLISAALLQDVHDLFFVPERAALMRESLAQRLRAGGGPFVVVAHSQGSMIAFDVLRQLK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
AADCEVSLFLTLGSPLGLPQVRSMFKRWTGTRKLPFPGCVQRWINVTETRDPIALDPDLT
HCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCHHCCCCCEEECCCCC
DDIANAKGRFENLAAARLNPDWQHNPHSASGYLSIPQVRAAVRQAVGVGFDQPVSNAVLI
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCCCHHHH
KDLSEQLEAHGPEHRHDVLIELDRRVLGNDPAGARALLLQHVRQAAARTTGLSGDALDEA
HHHHHHHHHCCCCCHHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IELEDSLQRFVSARLTRFEIESLQDRYRTLGFRRVWRNAGKRALIHVSGNVLHADAARTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECHHHHHH
YRARGQQIGWAVMDTGIAAGHPHFFLKGERDNVVAQWDCTRRGAPKRLTRADGTAFTRLD
HHHCCCCCCHHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHH
RHGHGTHIAGIIAGQCRASIPDASGTPGRTLEFSGMAPDTQLYGFKVLDDAGNGRDSWTI
CCCCCCEEEEEEECCHHCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCCHHHH
KAVQQVADINERAGELVIHGVNLSLGGCFDPESYGCGFTPLCNELRRLWRQGVLVVIAAG
HHHHHHHHHHHCCCEEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEC
NEGLAWLMRNDGDAYAANMDLSISDPGNLEDAIVVGSVHKSSPHNYGVSYFSSRGPTADG
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCC
RSKPDVVAPGEKILSAYYDFDPGDPAGLMVEMSGTSMAAPHVSGVLAGFLSARREFIGFP
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCH
DRVKQLLLDTCTDLQRDRYVQGRGVPNVMRMLGAT
HHHHHHHHHHHHHHHHHCEECCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]