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The map label for this gene is add [H]

Identifier: 77748521

GI number: 77748521

Start: 367666

End: 369216

Strand: Reverse

Name: add [H]

Synonym: XAC0308

Alternate gene names: 77748521

Gene position: 369216-367666 (Counterclockwise)

Preceding gene: 21241083

Following gene: 21241081

Centisome position: 7.13

GC content: 66.86

Gene sequence:

>1551_bases
ATGTTATTTCTTCGTCGCTGTCTGGTCCTGAGCGTATGGGCGTGCTTGCCCATCGTCGTGCACGCACGGCCAGCACCAGC
GCCTGCGCCTGCGCAACAACGCCAACAGCAGGTGGCGCGGTTGTTCCGTGAGGCGGCCGCGCAGCCGGCGCAGCTACGCA
CCTGGCTACAGGCCATGCCGAAAGGTGGCGACCTGCATAACCACCTGTCCGGTTCGGTGTATGCCGAGACGTATCTGCAA
TGGGCCAGCGACGACGGCGCCTGCGTGCAAGTGGACGACCTGAGCCTGCGCGCGCCGCCGTGCGGGGCCGGTCAGGAGTC
CGCGCGCGGCCTGGCGGCACGCAACGCCGCGCTGTACGGGCGGATGGTGAATTCGCTGTCGATGCGCAACTTCCTGCCCG
GCCCGGCGCAACCCAGCGGTCACGATCAGTTCTTCAGCACCTTCGGCAAGTTCGATGCGGTGGTCCGCACCCGTGTCGCC
GACACCGTCGCCGCAGTGCTGGAGCAGGCCGCACGCGACCGCGTGCCGTATGTGGAAATCATCGCCAACCCGCCGCAGAT
GGATCAGGCTGCCAAGCGCATGCAGTCGCTGCCGTGGAAGGGCGAGGACGACGCCGCCAATCTGCGTGCGTTGCAGCCCG
ACCTGGCGCCGCTGGTGCAGGCCGCGCAACGCGATCTTGCCGACATCGACGCGCAGGTCCGGCGCGTACTGCGTTGCGAC
CAGGCCGATGCACGCCCCGGCTGCACGGTCGAGTACCGCTATGTTCCGTATGTGTTGCGCGTGCTGCCGCAGCCGATGGT
GTTTGGGCAGATGGCGCTGGCGCATGCGCTGATCGCGGCCGGCGGCAGCCGCGCGGTGGCGCTGAACATCGTCGCGCCGG
AAGACAATCCAGTGGCGTTGGCCGATTACGCGCGGCATATGGCGATGTTCCGCTTCTTCGCAACGCGCTACCCCGGTGTG
CCGCTGTCGCTGCATGCCGGCGAGCTGGCGTTGGGGCTGGTGCCGCCGGCGCAGCTGCGCTCGCATATCCGGCAGGCGGT
GGATGCAGGTGCGCGCCGCATCGGTCACGGGGTGGATCTACCCTACGAAGACGATGCGGAGGTACTGCTGCAACGCATGC
GACGCGAACAGGTTGCGGTGGAGATCAACCTCACCAGCAACGATGTGATCCTGGGCATCAAAGGCGCCGCGCATCCGCTG
GCGCTGTATCTGCGTGCCGGCGTGCCGGTCGTGCTGTCCACCGACGATGCCGGCGTCTCGCGTGCGGACATGACCCACGA
GTACCAACGCGCGATGGAGGAACAGGGTATCGACTACCCCACCCTCAAACAGCTGGCCCGCAATGGCCTGCGCTACAGCT
TCCTGCCGGGTGCGAGCCTGTGGGATGCCGACGGTAAAGCTGCGCAGGTCTGCGCCACTGCGTTGCAGCGCGAAACAGAT
GATGCTGCCTGTCGAGCATTCCGCCAGGGCAGCGAGAAGGCTCGGCTGCAATGGCAGCTGGAAACCGACCTGGCCCAGTA
CGAGCGCACGCTGTTGCTGCAACACAGATAG

Upstream 100 bases:

>100_bases
CTTACCGGCGCGCACATGGGTGGCCTCGGGTCGCGCTGGCAGGCAAGCTATGTGGTCGCCGGCTGTCGCACGCCACCGTC
TCTCCAAACGAGTCTCCTGC

Downstream 100 bases:

>100_bases
CGCCGACAACGACACGACATATTCCACGTAGGAGCGCGCCCGAGCGCGAACGGACTTTACCGGTAACGCCCCGTCGCGCG
CAGGCACGCTCCTACAGATG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLFLRRCLVLSVWACLPIVVHARPAPAPAPAQQRQQQVARLFREAAAQPAQLRTWLQAMPKGGDLHNHLSGSVYAETYLQ
WASDDGACVQVDDLSLRAPPCGAGQESARGLAARNAALYGRMVNSLSMRNFLPGPAQPSGHDQFFSTFGKFDAVVRTRVA
DTVAAVLEQAARDRVPYVEIIANPPQMDQAAKRMQSLPWKGEDDAANLRALQPDLAPLVQAAQRDLADIDAQVRRVLRCD
QADARPGCTVEYRYVPYVLRVLPQPMVFGQMALAHALIAAGGSRAVALNIVAPEDNPVALADYARHMAMFRFFATRYPGV
PLSLHAGELALGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAEVLLQRMRREQVAVEINLTSNDVILGIKGAAHPL
ALYLRAGVPVVLSTDDAGVSRADMTHEYQRAMEEQGIDYPTLKQLARNGLRYSFLPGASLWDADGKAAQVCATALQRETD
DAACRAFRQGSEKARLQWQLETDLAQYERTLLLQHR

Sequences:

>Translated_516_residues
MLFLRRCLVLSVWACLPIVVHARPAPAPAPAQQRQQQVARLFREAAAQPAQLRTWLQAMPKGGDLHNHLSGSVYAETYLQ
WASDDGACVQVDDLSLRAPPCGAGQESARGLAARNAALYGRMVNSLSMRNFLPGPAQPSGHDQFFSTFGKFDAVVRTRVA
DTVAAVLEQAARDRVPYVEIIANPPQMDQAAKRMQSLPWKGEDDAANLRALQPDLAPLVQAAQRDLADIDAQVRRVLRCD
QADARPGCTVEYRYVPYVLRVLPQPMVFGQMALAHALIAAGGSRAVALNIVAPEDNPVALADYARHMAMFRFFATRYPGV
PLSLHAGELALGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAEVLLQRMRREQVAVEINLTSNDVILGIKGAAHPL
ALYLRAGVPVVLSTDDAGVSRADMTHEYQRAMEEQGIDYPTLKQLARNGLRYSFLPGASLWDADGKAAQVCATALQRETD
DAACRAFRQGSEKARLQWQLETDLAQYERTLLLQHR
>Mature_516_residues
MLFLRRCLVLSVWACLPIVVHARPAPAPAPAQQRQQQVARLFREAAAQPAQLRTWLQAMPKGGDLHNHLSGSVYAETYLQ
WASDDGACVQVDDLSLRAPPCGAGQESARGLAARNAALYGRMVNSLSMRNFLPGPAQPSGHDQFFSTFGKFDAVVRTRVA
DTVAAVLEQAARDRVPYVEIIANPPQMDQAAKRMQSLPWKGEDDAANLRALQPDLAPLVQAAQRDLADIDAQVRRVLRCD
QADARPGCTVEYRYVPYVLRVLPQPMVFGQMALAHALIAAGGSRAVALNIVAPEDNPVALADYARHMAMFRFFATRYPGV
PLSLHAGELALGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAEVLLQRMRREQVAVEINLTSNDVILGIKGAAHPL
ALYLRAGVPVVLSTDDAGVSRADMTHEYQRAMEEQGIDYPTLKQLARNGLRYSFLPGASLWDADGKAAQVCATALQRETD
DAACRAFRQGSEKARLQWQLETDLAQYERTLLLQHR

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Escherichia coli, GI1787910, Length=308, Percent_Identity=28.2467532467532, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 56605; Mature: 56605

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLRRCLVLSVWACLPIVVHARPAPAPAPAQQRQQQVARLFREAAAQPAQLRTWLQAMP
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
KGGDLHNHLSGSVYAETYLQWASDDGACVQVDDLSLRAPPCGAGQESARGLAARNAALYG
CCCCCHHHCCCCHHHHHHHHHCCCCCCEEEEECCEECCCCCCCCHHHHHHHHHHHHHHHH
RMVNSLSMRNFLPGPAQPSGHDQFFSTFGKFDAVVRTRVADTVAAVLEQAARDRVPYVEI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
IANPPQMDQAAKRMQSLPWKGEDDAANLRALQPDLAPLVQAAQRDLADIDAQVRRVLRCD
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
QADARPGCTVEYRYVPYVLRVLPQPMVFGQMALAHALIAAGGSRAVALNIVAPEDNPVAL
CCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEH
ADYARHMAMFRFFATRYPGVPLSLHAGELALGLVPPAQLRSHIRQAVDAGARRIGHGVDL
HHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
PYEDDAEVLLQRMRREQVAVEINLTSNDVILGIKGAAHPLALYLRAGVPVVLSTDDAGVS
CCCCCHHHHHHHHHHHCEEEEEEECCCCEEEEECCCCCHHHHHHHCCCCEEEECCCCCCC
RADMTHEYQRAMEEQGIDYPTLKQLARNGLRYSFLPGASLWDADGKAAQVCATALQRETD
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
DAACRAFRQGSEKARLQWQLETDLAQYERTLLLQHR
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA