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The map label for this gene is zwf [H]

Identifier: 21244798

GI number: 21244798

Start: 4782529

End: 4784367

Strand: Reverse

Name: zwf [H]

Synonym: XAC4081

Alternate gene names: 21244798

Gene position: 4784367-4782529 (Counterclockwise)

Preceding gene: 21244799

Following gene: 21244795

Centisome position: 92.44

GC content: 65.31

Gene sequence:

>1839_bases
ATGAGTGAGCAAGCAACCACACCGCCGTGCATCATCGTGGTGTTCGGCGCACGCGGCGATCTGACCAAGCGCCTGGTCAT
GCCGGCGCTGTACAACCTGCGCCGTTCCGGTGCGCTGGGCGATGATTTCGCCATTGTCGGCATGGACCATGGCGACATCA
GCGAGCGCGCCTGGCGGACCAACATGGGGCAGTCGATGACGCAGCTGCTCAGCAGCCGCGATGCCGAATTCCAGACCGAC
GAATTCGACACCGCCACCTGGGACTGGCTGCGCGAACGCATGCATTACCTGCGCGGCGACTTCACCGATCAGGGAGCCTA
TCGATCGCTGGGCGGCGTGCTGGACAAGCTGCACAAGCGCTACGGCACGCAGGGCAATGTGCTGTTCTATCTGGCCACCG
CCGCGCGCTTCTTCGAGCCGGTATTGCTCAACCTGGGCGAGGCTGGCCTGGTCAAGCAGCGCGAAGGCGAAGGCTGGCGC
CGGGTCATCGTGGAAAAACCCTTCGGCTACGATCTGCCCAGCGCCCAGCACCTCAATGCCACGGTCGCCAAGGTGCTGCA
CGAGGATCAGGTGTTCCGCATCGATCATTTCCTGGGCAAGGAAACCGTGCAGAACATTCTCGCGTTCCGCTTCGCCAATG
GCTTGTTCGAACCGGTGTGGAACCGCGACCGCATCGACCATGTGCAGATCACCGCGGCCGAAACCATCGGAGTGGAAGGG
CGCGGACGGTTCTACGACCCCACCGGCTGCCTGCGCGACATGGTGCCGAACCATCTGTTCCAGCTGCTGGCGATGATTGC
GATGGAGCCGCCAGCGGCCTTCACCACCGAGGCGATGCATCGCCGTCGCGCCGAAGTGATCGAAGCGGTGCGCCCGATCA
AACCCGAAGACGTGGTGCGCGGGCAATACGCCTCCGGTGCGGTCAATCGCAATGCGGTGCCGGGTTATCGCGAAGAAGAC
ACCGTGCCCGACGATTCGGACACCGAAACCTATGTGGCGATGAAGCTACAGGTGGACACCTGGCGCTGGGCCGGCGTGCC
GTTCTACCTGCGCACCGGTAAGCGCCTGCGCGAACGCACGACCGAGATCGCCATTCGCTTCAAGCCGGCACCGCTGGCGC
CCTTCCGCAGTACCGAGGTGGGCGGCTACGGCCCCGACTGGCTGGTGCTGCATATCCAGCCGGACGAGGGCATCTCGCTG
CAGTTCGACGTCAAGCGTCCGGGCGCGCAGGTGGCACTGGCACCGGTGCGCATGGACTTCCGTTACCGCGACTGGTTCCC
CAAGGAATACACGGTGGGCTACGAGCGCCTGCTGCAGGACTGCATGAACGGCGAAGCCGGCTTGTTCCAGGATGCGGCCA
TGGTGGAAGGCGCATGGCGCATCGTGCAACCGATCCTGGATGCATGGAAACAACCCCCAAGCGACTTCCCCAATTACGCC
GCCGGCAGCGCCGGCCCTTCGGCTGCCGATGCACTACTGGCAATGAATGGCGGACACGCCTGGCGCGCACTCACCCCAGG
GCGCAAGCCGCCACCGCGCCGGCCGCCGGAAGCGCGTGCTGGCGCTGCCGCGCCGATTAAGAAAACCACCGGCAAATCTG
CCAAGAAGGCCGCCAAGGCGCCGGCCGAGAAGGTCACCAAGGCGCCAGCCAGACGCGCATCTGCGGCTTCAGCAAGACCA
TCGCAGGATGCGGCTACGTCGCCTAGCAGCGCGGCCAGGAAGGCCGTGAGCAAACGCGTAACCGGCAAGGTCGCAAAGGC
CGCCGGCAAAACCGCGGCAGGCAAGGGCGCAGCGAAGAAGTCGGCCAGCAAGACCGTGGCGCGCACGCCACGCCGCTGA

Upstream 100 bases:

>100_bases
AACGCATGCTCGGCAACTTCCCGCAAGGGTATTCCCACGTGGCCCTGGTCAATGCGGCACTGCGCCTGCATGGACGCATG
GGCGAAAAGGAAACGCATCC

Downstream 100 bases:

>100_bases
CCGAGGCGAGCGGCCTACAGCCGCCGCAGCGCCACGTAGGAGCGTGCCTGCGCGCGACGTGCTTTGCCGGTAACGCCCGG
GGCGCGCGCAGGCACGCTCC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MSEQATTPPCIIVVFGARGDLTKRLVMPALYNLRRSGALGDDFAIVGMDHGDISERAWRTNMGQSMTQLLSSRDAEFQTD
EFDTATWDWLRERMHYLRGDFTDQGAYRSLGGVLDKLHKRYGTQGNVLFYLATAARFFEPVLLNLGEAGLVKQREGEGWR
RVIVEKPFGYDLPSAQHLNATVAKVLHEDQVFRIDHFLGKETVQNILAFRFANGLFEPVWNRDRIDHVQITAAETIGVEG
RGRFYDPTGCLRDMVPNHLFQLLAMIAMEPPAAFTTEAMHRRRAEVIEAVRPIKPEDVVRGQYASGAVNRNAVPGYREED
TVPDDSDTETYVAMKLQVDTWRWAGVPFYLRTGKRLRERTTEIAIRFKPAPLAPFRSTEVGGYGPDWLVLHIQPDEGISL
QFDVKRPGAQVALAPVRMDFRYRDWFPKEYTVGYERLLQDCMNGEAGLFQDAAMVEGAWRIVQPILDAWKQPPSDFPNYA
AGSAGPSAADALLAMNGGHAWRALTPGRKPPPRRPPEARAGAAAPIKKTTGKSAKKAAKAPAEKVTKAPARRASAASARP
SQDAATSPSSAARKAVSKRVTGKVAKAAGKTAAGKGAAKKSASKTVARTPRR

Sequences:

>Translated_612_residues
MSEQATTPPCIIVVFGARGDLTKRLVMPALYNLRRSGALGDDFAIVGMDHGDISERAWRTNMGQSMTQLLSSRDAEFQTD
EFDTATWDWLRERMHYLRGDFTDQGAYRSLGGVLDKLHKRYGTQGNVLFYLATAARFFEPVLLNLGEAGLVKQREGEGWR
RVIVEKPFGYDLPSAQHLNATVAKVLHEDQVFRIDHFLGKETVQNILAFRFANGLFEPVWNRDRIDHVQITAAETIGVEG
RGRFYDPTGCLRDMVPNHLFQLLAMIAMEPPAAFTTEAMHRRRAEVIEAVRPIKPEDVVRGQYASGAVNRNAVPGYREED
TVPDDSDTETYVAMKLQVDTWRWAGVPFYLRTGKRLRERTTEIAIRFKPAPLAPFRSTEVGGYGPDWLVLHIQPDEGISL
QFDVKRPGAQVALAPVRMDFRYRDWFPKEYTVGYERLLQDCMNGEAGLFQDAAMVEGAWRIVQPILDAWKQPPSDFPNYA
AGSAGPSAADALLAMNGGHAWRALTPGRKPPPRRPPEARAGAAAPIKKTTGKSAKKAAKAPAEKVTKAPARRASAASARP
SQDAATSPSSAARKAVSKRVTGKVAKAAGKTAAGKGAAKKSASKTVARTPRR
>Mature_611_residues
SEQATTPPCIIVVFGARGDLTKRLVMPALYNLRRSGALGDDFAIVGMDHGDISERAWRTNMGQSMTQLLSSRDAEFQTDE
FDTATWDWLRERMHYLRGDFTDQGAYRSLGGVLDKLHKRYGTQGNVLFYLATAARFFEPVLLNLGEAGLVKQREGEGWRR
VIVEKPFGYDLPSAQHLNATVAKVLHEDQVFRIDHFLGKETVQNILAFRFANGLFEPVWNRDRIDHVQITAAETIGVEGR
GRFYDPTGCLRDMVPNHLFQLLAMIAMEPPAAFTTEAMHRRRAEVIEAVRPIKPEDVVRGQYASGAVNRNAVPGYREEDT
VPDDSDTETYVAMKLQVDTWRWAGVPFYLRTGKRLRERTTEIAIRFKPAPLAPFRSTEVGGYGPDWLVLHIQPDEGISLQ
FDVKRPGAQVALAPVRMDFRYRDWFPKEYTVGYERLLQDCMNGEAGLFQDAAMVEGAWRIVQPILDAWKQPPSDFPNYAA
GSAGPSAADALLAMNGGHAWRALTPGRKPPPRRPPEARAGAAAPIKKTTGKSAKKAAKAPAEKVTKAPARRASAASARPS
QDAATSPSSAARKAVSKRVTGKVAKAAGKTAAGKGAAKKSASKTVARTPRR

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=490, Percent_Identity=34.2857142857143, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI108773793, Length=490, Percent_Identity=34.2857142857143, Blast_Score=283, Evalue=3e-76,
Organism=Homo sapiens, GI52145310, Length=371, Percent_Identity=30.9973045822102, Blast_Score=160, Evalue=3e-39,
Organism=Escherichia coli, GI1788158, Length=505, Percent_Identity=37.6237623762376, Blast_Score=338, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI17538218, Length=505, Percent_Identity=33.4653465346535, Blast_Score=295, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6324088, Length=489, Percent_Identity=33.7423312883436, Blast_Score=263, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24643350, Length=504, Percent_Identity=32.3412698412698, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24643352, Length=504, Percent_Identity=32.3412698412698, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI221513548, Length=484, Percent_Identity=29.9586776859504, Blast_Score=204, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 67614; Mature: 67482

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQATTPPCIIVVFGARGDLTKRLVMPALYNLRRSGALGDDFAIVGMDHGDISERAWRT
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NMGQSMTQLLSSRDAEFQTDEFDTATWDWLRERMHYLRGDFTDQGAYRSLGGVLDKLHKR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YGTQGNVLFYLATAARFFEPVLLNLGEAGLVKQREGEGWRRVIVEKPFGYDLPSAQHLNA
HCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
TVAKVLHEDQVFRIDHFLGKETVQNILAFRFANGLFEPVWNRDRIDHVQITAAETIGVEG
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCC
RGRFYDPTGCLRDMVPNHLFQLLAMIAMEPPAAFTTEAMHRRRAEVIEAVRPIKPEDVVR
CCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHC
GQYASGAVNRNAVPGYREEDTVPDDSDTETYVAMKLQVDTWRWAGVPFYLRTGKRLRERT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCEECCCHHHHHHH
TEIAIRFKPAPLAPFRSTEVGGYGPDWLVLHIQPDEGISLQFDVKRPGAQVALAPVRMDF
HEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEEEECC
RYRDWFPKEYTVGYERLLQDCMNGEAGLFQDAAMVEGAWRIVQPILDAWKQPPSDFPNYA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AGSAGPSAADALLAMNGGHAWRALTPGRKPPPRRPPEARAGAAAPIKKTTGKSAKKAAKA
CCCCCCHHHHHEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHCC
PAEKVTKAPARRASAASARPSQDAATSPSSAARKAVSKRVTGKVAKAAGKTAAGKGAAKK
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
SASKTVARTPRR
HHHHHHHCCCCC
>Mature Secondary Structure 
SEQATTPPCIIVVFGARGDLTKRLVMPALYNLRRSGALGDDFAIVGMDHGDISERAWRT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NMGQSMTQLLSSRDAEFQTDEFDTATWDWLRERMHYLRGDFTDQGAYRSLGGVLDKLHKR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YGTQGNVLFYLATAARFFEPVLLNLGEAGLVKQREGEGWRRVIVEKPFGYDLPSAQHLNA
HCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
TVAKVLHEDQVFRIDHFLGKETVQNILAFRFANGLFEPVWNRDRIDHVQITAAETIGVEG
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCC
RGRFYDPTGCLRDMVPNHLFQLLAMIAMEPPAAFTTEAMHRRRAEVIEAVRPIKPEDVVR
CCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHC
GQYASGAVNRNAVPGYREEDTVPDDSDTETYVAMKLQVDTWRWAGVPFYLRTGKRLRERT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCEECCCHHHHHHH
TEIAIRFKPAPLAPFRSTEVGGYGPDWLVLHIQPDEGISLQFDVKRPGAQVALAPVRMDF
HEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEEEECC
RYRDWFPKEYTVGYERLLQDCMNGEAGLFQDAAMVEGAWRIVQPILDAWKQPPSDFPNYA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AGSAGPSAADALLAMNGGHAWRALTPGRKPPPRRPPEARAGAAAPIKKTTGKSAKKAAKA
CCCCCCHHHHHEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHCC
PAEKVTKAPARRASAASARPSQDAATSPSSAARKAVSKRVTGKVAKAAGKTAAGKGAAKK
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
SASKTVARTPRR
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]