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The map label for this gene is gst [H]

Identifier: 21244764

GI number: 21244764

Start: 4739735

End: 4740424

Strand: Reverse

Name: gst [H]

Synonym: XAC4047

Alternate gene names: 21244764

Gene position: 4740424-4739735 (Counterclockwise)

Preceding gene: 21244770

Following gene: 21244763

Centisome position: 91.59

GC content: 63.91

Gene sequence:

>690_bases
ATGATCGATCTGTACTACTGGCCCACGCCCAACGGGCACAAAATCACGCTGTTTCTGGAAGAGGCCGGGCTGCAGTACAC
CCTCAAGCCGGTCAACATCGGCAAGGGCGAACAATTCGAACCGGCATTCCTGCAGATTTCGCCCAACAACAAGATGCCGG
CCATCGTCGACCATGCACCGGCCGATGGCGGCGGTGCGCAGAGCGTGTTCGAGTCCGGCGCGATCCTGCTGTATCTGGCC
AAGAAGACCGGCCGCTTCCTGCCGCGCGATGCCCGCGGCCGGATCGCTGCACTGGAGTGGCTGTTCTGGCAGATGGGCGG
GCTGGGCCCGATGAGCGGTCAGATGGGTCACTTCAACGTCTATGCACCGGAAAAGATTGCGTACGCGATCGAGCGCTACA
ACGCCGAGGTGCGTCGCCTGCATGGCGTGCTCGACAAGCGCCTGGCCGACCACGCCTTCCTGGCCGGCGACGACTACGGC
ATTGCCGACATGGCCAGCTATCCGTGGATCGAAGTCTATGGCGACCTCAAACCCGACTACGCCGCCTTCCCCCATCTGAA
GCGCTGGCACGACGCCATCGCCGCGCGCCCGGCGACCCAGCGCGCCTACGCGCTCAAGGAGCAGGTCAATCCCAATGCGG
GCCAGCCGCTCAGCGATGAAGAGCGCAAGCACCTGTTCGGCAAGCGTTGA

Upstream 100 bases:

>100_bases
GTCAGGCGCCACGGCGCTTCCGGTCCGACGCCTGCATGATAGGCATGCCGCCGTGCGTCATGTCTGCCGCAACGACCCCA
CCTTATGACTGGAGCGCACG

Downstream 100 bases:

>100_bases
AGCAACGTCGTAGCAGCGGTTGCGTAACAGGACACGCGCATCAAACGCGCGCGACACATCAACGGGGCCGCACGAGCCCC
TCTCCCCCGGGAGAGGGGTG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIDLYYWPTPNGHKITLFLEEAGLQYTLKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPADGGGAQSVFESGAILLYLA
KKTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIAYAIERYNAEVRRLHGVLDKRLADHAFLAGDDYG
IADMASYPWIEVYGDLKPDYAAFPHLKRWHDAIAARPATQRAYALKEQVNPNAGQPLSDEERKHLFGKR

Sequences:

>Translated_229_residues
MIDLYYWPTPNGHKITLFLEEAGLQYTLKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPADGGGAQSVFESGAILLYLA
KKTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIAYAIERYNAEVRRLHGVLDKRLADHAFLAGDDYG
IADMASYPWIEVYGDLKPDYAAFPHLKRWHDAIAARPATQRAYALKEQVNPNAGQPLSDEERKHLFGKR
>Mature_229_residues
MIDLYYWPTPNGHKITLFLEEAGLQYTLKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPADGGGAQSVFESGAILLYLA
KKTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIAYAIERYNAEVRRLHGVLDKRLADHAFLAGDDYG
IADMASYPWIEVYGDLKPDYAAFPHLKRWHDAIAARPATQRAYALKEQVNPNAGQPLSDEERKHLFGKR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=60.7655502392344, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI87082195, Length=223, Percent_Identity=42.6008968609865, Blast_Score=172, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=32.7586206896552, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17864592, Length=202, Percent_Identity=27.2277227722772, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571670, Length=174, Percent_Identity=26.4367816091954, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864594, Length=203, Percent_Identity=26.6009852216749, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17864598, Length=199, Percent_Identity=27.6381909547739, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17933730, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85725204, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17737923, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24646249, Length=195, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25683; Mature: 25683

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWPTPNGHKITLFLEEAGLQYTLKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAP
CCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGGAQSVFESGAILLYLAKKTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNV
CCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEKIAYAIERYNAEVRRLHGVLDKRLADHAFLAGDDYGIADMASYPWIEVYGDLKPDY
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHCCCCEEEEECCCCCCH
AAFPHLKRWHDAIAARPATQRAYALKEQVNPNAGQPLSDEERKHLFGKR
HHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MIDLYYWPTPNGHKITLFLEEAGLQYTLKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAP
CCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGGAQSVFESGAILLYLAKKTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNV
CCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEKIAYAIERYNAEVRRLHGVLDKRLADHAFLAGDDYGIADMASYPWIEVYGDLKPDY
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHCCCCEEEEECCCCCCH
AAFPHLKRWHDAIAARPATQRAYALKEQVNPNAGQPLSDEERKHLFGKR
HHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]