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The map label for this gene is uvrD [C]

Identifier: 21244660

GI number: 21244660

Start: 4634759

End: 4636588

Strand: Reverse

Name: uvrD [C]

Synonym: XAC3941

Alternate gene names: 21244660

Gene position: 4636588-4634759 (Counterclockwise)

Preceding gene: 21244661

Following gene: 21244657

Centisome position: 89.59

GC content: 58.2

Gene sequence:

>1830_bases
TTGCCAGCCTGGCCCGAAGAAGGGCGAGGACGAATGAGCACGGATACTCCTTCATTAGAACAGGGTGCGATCATCACGGC
ACCATTGCAGCCGATGTCGGTCATCGCTTGTGCGGGAAGTGGTAAGACATTCACGGCTGTACGAAGACTCGCTCACATAC
GTCGATGCCTCGGTGATCACCGGGGCCGGGTTGCGCTCCTGTCCTTCTCGAACATCGCAGTCGAGACCTTCAGGCGCGAG
TACCAAGCACTTGCCGTGGGATCGCTCAAGATCCCGTCCCACCAGCGCGTTGAGATCGACACACTGGACGGGTTCATTAC
GACAAACATTCTGCGACCTCACGCCCATCGGACAATGGGATGTACCACGACCCCGTTCTTGCTATCAGGAAGCGAGTCGT
TCCTGCTAGGAAAGGACTATCGCTTTTGGGTGGAATCGCCGAGAACCGGTAACTACCCGGTGCCCCAAGCGCATATCCAT
CGCGTTGTTATAGGCCCTTCAGGGGCTGGAACGGACTTCTTCTACCAGAACTCCGGCATGCTGACGAGAATCAACAATGG
CCCCAAGGCTGCCGCAGCCTTGGGAAAACTGGGGGCTTACACCCACGAGCTGGCGCGCTACTGGGCCGACCTCACCCTCC
GCGAACAACCCGAGATCCTGCGCGTACTCGCGCGTCGCTATCCCCACATCCTCATTGATGAAGCGCAGGATATCGGGATC
CTGCACCAGTTGATCATTGAAAGGCTCAGCCAAGCAGGCTCTCAAATCTCCCTCATTGGCGATCCCAATCAGGGCATCTA
CGAGTTCATGGGTGCCACCGGCTCGTTCCTGTCCAGCTACCACAGCAAACCCGGTGTTGCTCCGGCAGCCCTGACACGCA
ACTATCGGTCCGTACCGGCCGTACTCGATCTAGCCAATGCAATCTCAGCGCGTACGGACGAACCGGATAGGCACGCGCCA
CTTACGCTCCACGGAGCCTACTTCGTTCCGTACACGACTACCAGTACGCAGAATGTCCTGGCGGCCTTCCAGGCGACACT
GATGTCTGCTGGCTTGGACCCTGGACGTTCCGCCGTACTCTGCCGTGCACGAAAGTGGGCCAACGAGCTGGCCGGGAGTG
AGGGTGCCCCTGGTGTTGGAACGACGAAGATGCTTGCCCAAGCGGCGATGGTGCGCGATATCCACTCTGACTACTCAACA
GCATTCAGACTCGTGGCAACTGCCATCATAGGTTTGACCGACAACGCACCCAAGGGCATCGTTGCTCGCCTAACTCAGCC
AGCCAGGTACCCAGAAGAACGAGCGCTTCGTCGCGCTGTTTGGGCTTTCACCAGAGATTCGGTAGCAGGTCTGCCTAGTG
CGTCGCTACCCGCCGTAAGCGATTGGCAGCCGACATTGTTGCAACGTGTCAGGGTCCTGATGACGAATCTGAGCACGGCT
CATGGACTTAATCACACCTCGTCCAAGCTCGGCAGTCGGCTCTCAAAGAAGAGTTTATCCAGTTCGCCGCTAATGAGCCC
GCCGGACCTAGGTGCAGATCAACCCCTGCGGATCAGAATTAGCACCGTGCACCAAGTCAAAGGCGAAAGCCTGGATGCCG
TCCTCTACATGGCAACGAAGGCGCATGTATCTGCACTCTTAGACGGGGGTTCCACTGAGGATGGGCGAATTGGATACGTG
GCTGTGACCCGAGCAAGGGATCTGCTGTGGCTGGGTGTTCCGGCGACAGCTTTGAAGATCCTTCGTGCCGATCTTGAAGC
GAAAGGCTTCAAGGACGCAACCGCTAAGATTGCGGCCCCTCCTGCCGGGCATGGCATAGGTACCCCCTGA

Upstream 100 bases:

>100_bases
AGAAGGGGCGCTTTGCACAAGCTTTGGCGCACCTTATCGCTAAAGCGAAAGCCGAAGATTTCATTGTCCCCGGGTACATC
AAGTCTGCAGTTGAACACGC

Downstream 100 bases:

>100_bases
GTGGGAAGACCGGATAAAAGCCCAGCCCGTCACCAGCATCAAATCAACGCCCAAAGACGAAGAAGAATGGGGGCAATCAG
AGGTTCTCTCCCATAACGGG

Product: DNA helicase

Products: NA

Alternate protein names: ATP-Dependent DNA Helicase; DNA/RNA Helicase; ATP-Dependent DNA Helicase UvrD; DNA Helicase

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MPAWPEEGRGRMSTDTPSLEQGAIITAPLQPMSVIACAGSGKTFTAVRRLAHIRRCLGDHRGRVALLSFSNIAVETFRRE
YQALAVGSLKIPSHQRVEIDTLDGFITTNILRPHAHRTMGCTTTPFLLSGSESFLLGKDYRFWVESPRTGNYPVPQAHIH
RVVIGPSGAGTDFFYQNSGMLTRINNGPKAAAALGKLGAYTHELARYWADLTLREQPEILRVLARRYPHILIDEAQDIGI
LHQLIIERLSQAGSQISLIGDPNQGIYEFMGATGSFLSSYHSKPGVAPAALTRNYRSVPAVLDLANAISARTDEPDRHAP
LTLHGAYFVPYTTTSTQNVLAAFQATLMSAGLDPGRSAVLCRARKWANELAGSEGAPGVGTTKMLAQAAMVRDIHSDYST
AFRLVATAIIGLTDNAPKGIVARLTQPARYPEERALRRAVWAFTRDSVAGLPSASLPAVSDWQPTLLQRVRVLMTNLSTA
HGLNHTSSKLGSRLSKKSLSSSPLMSPPDLGADQPLRIRISTVHQVKGESLDAVLYMATKAHVSALLDGGSTEDGRIGYV
AVTRARDLLWLGVPATALKILRADLEAKGFKDATAKIAAPPAGHGIGTP

Sequences:

>Translated_609_residues
MPAWPEEGRGRMSTDTPSLEQGAIITAPLQPMSVIACAGSGKTFTAVRRLAHIRRCLGDHRGRVALLSFSNIAVETFRRE
YQALAVGSLKIPSHQRVEIDTLDGFITTNILRPHAHRTMGCTTTPFLLSGSESFLLGKDYRFWVESPRTGNYPVPQAHIH
RVVIGPSGAGTDFFYQNSGMLTRINNGPKAAAALGKLGAYTHELARYWADLTLREQPEILRVLARRYPHILIDEAQDIGI
LHQLIIERLSQAGSQISLIGDPNQGIYEFMGATGSFLSSYHSKPGVAPAALTRNYRSVPAVLDLANAISARTDEPDRHAP
LTLHGAYFVPYTTTSTQNVLAAFQATLMSAGLDPGRSAVLCRARKWANELAGSEGAPGVGTTKMLAQAAMVRDIHSDYST
AFRLVATAIIGLTDNAPKGIVARLTQPARYPEERALRRAVWAFTRDSVAGLPSASLPAVSDWQPTLLQRVRVLMTNLSTA
HGLNHTSSKLGSRLSKKSLSSSPLMSPPDLGADQPLRIRISTVHQVKGESLDAVLYMATKAHVSALLDGGSTEDGRIGYV
AVTRARDLLWLGVPATALKILRADLEAKGFKDATAKIAAPPAGHGIGTP
>Mature_608_residues
PAWPEEGRGRMSTDTPSLEQGAIITAPLQPMSVIACAGSGKTFTAVRRLAHIRRCLGDHRGRVALLSFSNIAVETFRREY
QALAVGSLKIPSHQRVEIDTLDGFITTNILRPHAHRTMGCTTTPFLLSGSESFLLGKDYRFWVESPRTGNYPVPQAHIHR
VVIGPSGAGTDFFYQNSGMLTRINNGPKAAAALGKLGAYTHELARYWADLTLREQPEILRVLARRYPHILIDEAQDIGIL
HQLIIERLSQAGSQISLIGDPNQGIYEFMGATGSFLSSYHSKPGVAPAALTRNYRSVPAVLDLANAISARTDEPDRHAPL
TLHGAYFVPYTTTSTQNVLAAFQATLMSAGLDPGRSAVLCRARKWANELAGSEGAPGVGTTKMLAQAAMVRDIHSDYSTA
FRLVATAIIGLTDNAPKGIVARLTQPARYPEERALRRAVWAFTRDSVAGLPSASLPAVSDWQPTLLQRVRVLMTNLSTAH
GLNHTSSKLGSRLSKKSLSSSPLMSPPDLGADQPLRIRISTVHQVKGESLDAVLYMATKAHVSALLDGGSTEDGRIGYVA
VTRARDLLWLGVPATALKILRADLEAKGFKDATAKIAAPPAGHGIGTP

Specific function: Has Both Atpase And Helicase Activities. Unwinds DNA Duplexes With 3' To 5' Polarity With Respect To The Bound Strand And Initiates Unwinding Most Effectively When A Single-Stranded Region Is Present. Involved In The Post-Incision Events Of Nucleotide Exc

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 65627; Mature: 65496

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAWPEEGRGRMSTDTPSLEQGAIITAPLQPMSVIACAGSGKTFTAVRRLAHIRRCLGDH
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
RGRVALLSFSNIAVETFRREYQALAVGSLKIPSHQRVEIDTLDGFITTNILRPHAHRTMG
CCCEEEEEECHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCC
CTTTPFLLSGSESFLLGKDYRFWVESPRTGNYPVPQAHIHRVVIGPSGAGTDFFYQNSGM
CCCCCEEEECCCCEEECCCEEEEECCCCCCCCCCCHHHEEEEEECCCCCCCCEEEECCCC
LTRINNGPKAAAALGKLGAYTHELARYWADLTLREQPEILRVLARRYPHILIDEAQDIGI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCHHHHH
LHQLIIERLSQAGSQISLIGDPNQGIYEFMGATGSFLSSYHSKPGVAPAALTRNYRSVPA
HHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHCCCCCCHH
VLDLANAISARTDEPDRHAPLTLHGAYFVPYTTTSTQNVLAAFQATLMSAGLDPGRSAVL
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHH
CRARKWANELAGSEGAPGVGTTKMLAQAAMVRDIHSDYSTAFRLVATAIIGLTDNAPKGI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
VARLTQPARYPEERALRRAVWAFTRDSVAGLPSASLPAVSDWQPTLLQRVRVLMTNLSTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HGLNHTSSKLGSRLSKKSLSSSPLMSPPDLGADQPLRIRISTVHQVKGESLDAVLYMATK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCEEEEHHHH
AHVSALLDGGSTEDGRIGYVAVTRARDLLWLGVPATALKILRADLEAKGFKDATAKIAAP
HHHHHHHCCCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECC
PAGHGIGTP
CCCCCCCCC
>Mature Secondary Structure 
PAWPEEGRGRMSTDTPSLEQGAIITAPLQPMSVIACAGSGKTFTAVRRLAHIRRCLGDH
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
RGRVALLSFSNIAVETFRREYQALAVGSLKIPSHQRVEIDTLDGFITTNILRPHAHRTMG
CCCEEEEEECHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCC
CTTTPFLLSGSESFLLGKDYRFWVESPRTGNYPVPQAHIHRVVIGPSGAGTDFFYQNSGM
CCCCCEEEECCCCEEECCCEEEEECCCCCCCCCCCHHHEEEEEECCCCCCCCEEEECCCC
LTRINNGPKAAAALGKLGAYTHELARYWADLTLREQPEILRVLARRYPHILIDEAQDIGI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCHHHHH
LHQLIIERLSQAGSQISLIGDPNQGIYEFMGATGSFLSSYHSKPGVAPAALTRNYRSVPA
HHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHCCCCCCHH
VLDLANAISARTDEPDRHAPLTLHGAYFVPYTTTSTQNVLAAFQATLMSAGLDPGRSAVL
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHH
CRARKWANELAGSEGAPGVGTTKMLAQAAMVRDIHSDYSTAFRLVATAIIGLTDNAPKGI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
VARLTQPARYPEERALRRAVWAFTRDSVAGLPSASLPAVSDWQPTLLQRVRVLMTNLSTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HGLNHTSSKLGSRLSKKSLSSSPLMSPPDLGADQPLRIRISTVHQVKGESLDAVLYMATK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCEEEEHHHH
AHVSALLDGGSTEDGRIGYVAVTRARDLLWLGVPATALKILRADLEAKGFKDATAKIAAP
HHHHHHHCCCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECC
PAGHGIGTP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA