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The map label for this gene is yhcS [C]

Identifier: 21244497

GI number: 21244497

Start: 4448376

End: 4449239

Strand: Reverse

Name: yhcS [C]

Synonym: XAC3772

Alternate gene names: 21244497

Gene position: 4449239-4448376 (Counterclockwise)

Preceding gene: 21244500

Following gene: 21244496

Centisome position: 85.97

GC content: 67.01

Gene sequence:

>864_bases
ATGGAAGACCTCAACGACTTTGCGCTGCTGGCGGCGGTGGTCGACCACGGCAGCTTCTCGGCGGCCGGTCGCGCGTTGGG
GTTTCCCCGCTCCAAGGTCAGCCGGCGGGTGGCAGATCTGGAGCAACGCCTGGGCGTGCGGCTGTTGCAGCGTTCAACCC
GTGCGGTCAGCCTCACCGAAGTCGGTGCCGAGTTCTATACGCACTGCAAATCCATCACCCGCTCGGCGCAATGGGCGCTG
GATGTGGCCGAGCGCGCCACGCAGCATCCCTCCGGCCGGATCTGGGTGAGCTGCCCGACCGGTGTGGCGCATCTGTTTCT
GGCCGAGCTCTTGCCGCGCTTTTTGTTGACGCATCCGGACGTGCAGGTGGATCTGGAGCTGACCAGTCGCCGGGTGGAAC
CGATTGCCGAAAGCATCGACGTGGCGATACGGGTGCGTTCGAGCCTGGACGATTCGGGCTTGATCCTGCGTTCGTTCGGC
GTCAGCCGGCAGGTCTTGGTGGCAAGCCCAGGCTTCGTGCACGCGCATGGGCCGTTCGTCTCTGCCGCGGCATTGCACGA
GGTACTGGGAATGGGCCCGCGTGGCGTCAATGGCGAGCCGCCCCGGTGGCGGCTCACCAGCCCGCAAGGCACCAGCGAAC
TGGTGGACTACCGTGTTCGCGCTTGTTCACCGAGGACGTCGAACTGCTGCACCACGCTGCGTTGGCCGGCATGGGCGTGG
CGCAGTTGCCGCTGGCCCTGTGCAGGGGCAGCATCGCCCGTGGCGAACTGGTGGTGCTGTTGGGCGACCACACGTTGCCG
GCGCATCAACTACACGCCGTGTATCCCTCGCGTCGCGGACTGGCGCCGGGCGTGCGCGCCTTGA

Upstream 100 bases:

>100_bases
CTGTACGGAGTGGTCCCGTGCGCAGGTAGGTCGCTGGCGGATGACAAGCTGTCCTGCCTGGCAGGACAATGACGGCCTCC
TTGCGTGGGGTTTGATTCAG

Downstream 100 bases:

>100_bases
TCGAGTTCCTGGTCGACGTCCTGCCTGCGGTGCTGGAGAGCGCCGAACACGGCGTGTCGGGCTAGCGCATGCAGGGCCCG
CCGCGACACGCTGGGTCCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MEDLNDFALLAAVVDHGSFSAAGRALGFPRSKVSRRVADLEQRLGVRLLQRSTRAVSLTEVGAEFYTHCKSITRSAQWAL
DVAERATQHPSGRIWVSCPTGVAHLFLAELLPRFLLTHPDVQVDLELTSRRVEPIAESIDVAIRVRSSLDDSGLILRSFG
VSRQVLVASPGFVHAHGPFVSAAALHEVLGMGPRGVNGEPPRWRLTSPQGTSELVDYRVRACSPRTSNCCTTLRWPAWAW
RSCRWPCAGAASPVANWWCCWATTRCRRINYTPCIPRVADWRRACAP

Sequences:

>Translated_287_residues
MEDLNDFALLAAVVDHGSFSAAGRALGFPRSKVSRRVADLEQRLGVRLLQRSTRAVSLTEVGAEFYTHCKSITRSAQWAL
DVAERATQHPSGRIWVSCPTGVAHLFLAELLPRFLLTHPDVQVDLELTSRRVEPIAESIDVAIRVRSSLDDSGLILRSFG
VSRQVLVASPGFVHAHGPFVSAAALHEVLGMGPRGVNGEPPRWRLTSPQGTSELVDYRVRACSPRTSNCCTTLRWPAWAW
RSCRWPCAGAASPVANWWCCWATTRCRRINYTPCIPRVADWRRACAP
>Mature_287_residues
MEDLNDFALLAAVVDHGSFSAAGRALGFPRSKVSRRVADLEQRLGVRLLQRSTRAVSLTEVGAEFYTHCKSITRSAQWAL
DVAERATQHPSGRIWVSCPTGVAHLFLAELLPRFLLTHPDVQVDLELTSRRVEPIAESIDVAIRVRSSLDDSGLILRSFG
VSRQVLVASPGFVHAHGPFVSAAALHEVLGMGPRGVNGEPPRWRLTSPQGTSELVDYRVRACSPRTSNCCTTLRWPAWAW
RSCRWPCAGAASPVANWWCCWATTRCRRINYTPCIPRVADWRRACAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=282, Percent_Identity=30.8510638297872, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789440, Length=172, Percent_Identity=30.2325581395349, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786401, Length=173, Percent_Identity=34.6820809248555, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787128, Length=143, Percent_Identity=34.2657342657343, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693193, Length=177, Percent_Identity=30.5084745762712, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081978, Length=174, Percent_Identity=29.8850574712644, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787589, Length=206, Percent_Identity=25.2427184466019, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31780; Mature: 31780

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLNDFALLAAVVDHGSFSAAGRALGFPRSKVSRRVADLEQRLGVRLLQRSTRAVSLTE
CCCHHHHHHHHHHHHCCCCHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHH
VGAEFYTHCKSITRSAQWALDVAERATQHPSGRIWVSCPTGVAHLFLAELLPRFLLTHPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
VQVDLELTSRRVEPIAESIDVAIRVRSSLDDSGLILRSFGVSRQVLVASPGFVHAHGPFV
CEEEHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCEEEEECCCEEECCCCHH
SAAALHEVLGMGPRGVNGEPPRWRLTSPQGTSELVDYRVRACSPRTSNCCTTLRWPAWAW
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHH
RSCRWPCAGAASPVANWWCCWATTRCRRINYTPCIPRVADWRRACAP
HCCCCCCCCCCCCHHHHEEEHHHHHHCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MEDLNDFALLAAVVDHGSFSAAGRALGFPRSKVSRRVADLEQRLGVRLLQRSTRAVSLTE
CCCHHHHHHHHHHHHCCCCHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHH
VGAEFYTHCKSITRSAQWALDVAERATQHPSGRIWVSCPTGVAHLFLAELLPRFLLTHPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
VQVDLELTSRRVEPIAESIDVAIRVRSSLDDSGLILRSFGVSRQVLVASPGFVHAHGPFV
CEEEHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCEEEEECCCEEECCCCHH
SAAALHEVLGMGPRGVNGEPPRWRLTSPQGTSELVDYRVRACSPRTSNCCTTLRWPAWAW
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHH
RSCRWPCAGAASPVANWWCCWATTRCRRINYTPCIPRVADWRRACAP
HCCCCCCCCCCCCHHHHEEEHHHHHHCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]