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The map label for this gene is dadA

Identifier: 21244413

GI number: 21244413

Start: 4365148

End: 4366437

Strand: Reverse

Name: dadA

Synonym: XAC3688

Alternate gene names: 21244413

Gene position: 4366437-4365148 (Counterclockwise)

Preceding gene: 21244415

Following gene: 21244412

Centisome position: 84.37

GC content: 68.76

Gene sequence:

>1290_bases
ATGCGTGTGCTCATTCTCGGTAGCGGCGTCATCGGCGTGACCAGTGCGTGGTACCTGGCGCAGGCCGGTTGCGAAGTGAC
CGTGGTCGACCGCCAGCCGGCGGCGGCGCTGGAGACCAGCTACGCCAACGCCGGCCAGCTGTCGTTCGGCTACACCTCCC
CCTGGGCCGCACCCGGCGTGCCTGGCAAGGCGGTGAAGTGGCTGTTCGAGCAGCACGCACCGCTGTCGATCCGCCCCACC
CGCGACCTGCGCCAGCTGGCCTGGCTGAGCCAGATGCTGCGCAACTGCACCGCCGAGCGCTATGCGGTGAACAAGGCGCG
CATGGTGCGCATGTCCGACTACAGCCGCGATTGCCTCAACGCCTTGCGCGCCGAGACCGGCATCGAATTCGAAGGCCGCC
AGCTGGGCACCACGCAGTTGTTCCGCACCCAGCAGCAGCTGGACGCGGCCGCGCAGGACATCGAAGTGCTGGCCCAGTAC
GGGGTGCCGTACGAGCTGCTGAGCCCGGCGCAGATTGCGCAGTTCGAACCTGGCCTGGCCGGCGGCGGCGCGCAGATGGC
CGGCGCGTTGCGCCTGCCCGAAGACCAGACCGGTGACTGCCGCCTGTTTACCCAACGCCTGGCCGAACTGGCCACGCAGG
CAGGTGTCACGTTCCGCTATGGGCAGCAGATCGAGCGGCTGGAGCATGCCGGCGGCCAAATCACTGGCGTGCAGATCGAT
GGCCGCATCGAGACCGCCGACCGCTACGTGCTGGCGCTGGGCAGCTATTCGGCCGACGTGCTGCTCTCGCTCGGCCTGCA
TTTGCCGGTGTACCCGCTCAAGGGCTATTCGCTGACCATCCCGATCGTCGATGCGCAGCGCGCGCCGACCTCTACGGTGC
TGGACGAGAGCTACAAGATCGCGCTCACCCGTTTCGACGACCGTATCCGCGTCGGCGGCATGGCCGAGGTGGCCGGCTTC
GACATGTCCTTGAATCCGCGTCGTCGCGCCACCCTGGAAATGGTGGTCAACGACCTGTTCCCCGGCGGCGGCGATCTGGC
CCAGGCCGAGTTCTGGACCGGCTTGCGGCCGGCCACCCCGGATGGCACCCCGGTGGTCGGCGCCACGCCGTATGCCAACC
TGTTCCTCAACACCGGTCACGGCACGCTGGGCTGGACCATGGCCTGCGGTTCCGGGCGCTATCTGGCCGACCTCATGCAG
GGCCGCACGCCCGAGATCGATACCGAAGGCCTGGACGTGTTCCGCTACCTGTCGCCGCGCAGCGTGCGCCCGCATCGGGA
GGCCGCGTAG

Upstream 100 bases:

>100_bases
GCTGATTCCAGAAATGGCACTGCCTGGCTCGCAATATACTGCGTCTAACTGTCCCCCTCTGTGCGTAGTTCTGGGGGAAT
GCCCTTTTCAGGAGAACGAC

Downstream 100 bases:

>100_bases
TGCGTCCTGCGCAAGCGTCGATCGATCTGGAGGCATTGCGCCACAACTACCGCCTGGCCAAGCGCCTGGGCGGCAGCAAG
GCGCTGGCGGTGGTCAAGGC

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELATQAGVTFRYGQQIERLEHAGGQITGVQID
GRIETADRYVLALGSYSADVLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSVRPHREAA

Sequences:

>Translated_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELATQAGVTFRYGQQIERLEHAGGQITGVQID
GRIETADRYVLALGSYSADVLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSVRPHREAA
>Mature_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELATQAGVTFRYGQQIERLEHAGGQITGVQID
GRIETADRYVLALGSYSADVLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTEGLDVFRYLSPRSVRPHREAA

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Homo sapiens, GI194306651, Length=337, Percent_Identity=25.8160237388724, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787438, Length=426, Percent_Identity=61.5023474178404, Blast_Score=529, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA_XANAC (Q8PGC9)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643995.1
- ProteinModelPortal:   Q8PGC9
- GeneID:   1157759
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3688
- NMPDR:   fig|190486.1.peg.3639
- HOGENOM:   HBG729204
- OMA:   LEHAGGQ
- ProtClustDB:   PRK00711
- BioCyc:   XAXO190486:XAC3688-MONOMER
- BRENDA:   1.4.99.1
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 46676; Mature: 46676

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELATQAGVTFRYGQQIERLEHAGGQITGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEEEC
GRIETADRYVLALGSYSADVLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEECCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTEGLDVFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SVRPHREAA
CCCCCCCCC
>Mature Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELATQAGVTFRYGQQIERLEHAGGQITGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEEEC
GRIETADRYVLALGSYSADVLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEECCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTEGLDVFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SVRPHREAA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217