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The map label for this gene is uptB [H]

Identifier: 21244333

GI number: 21244333

Start: 4280013

End: 4280675

Strand: Reverse

Name: uptB [H]

Synonym: XAC3608

Alternate gene names: 21244333

Gene position: 4280675-4280013 (Counterclockwise)

Preceding gene: 77748733

Following gene: 21244331

Centisome position: 82.71

GC content: 68.48

Gene sequence:

>663_bases
ATGAGCGCGGCCCTGGAGCTGTTTTCGTACTGGCGTTCGAGCGCGGCCTATCGCGTGCGCATCGGTCTGGGGCTGAAGGC
GCTGGACTACATCGCCCAGCCGGTGCATCTGGTGCGTGACGGGGGCGAGCAGCACGCGCCGGCCTATGCGCAACTCAATC
CGCAGGAACTGGTGCCGACGTTGCGGCATGGCGATGTGGTGATCGCACAGTCGCTAGCGATTCTGGAGTATCTGGAAGAG
GCATTCGCGGACACCGCGGCGCTGCTGCCGCGCGCGCCTGCCGAACGCGCCCGGGTGCGCGCACTGGCGCAGCTCATCGC
CTGCGATGTGCACCCGCTCAACAACCTGCGCGTCATGCAGGTGCTGGAGCGCGAGTTCGCGCTGGATGGCGCACGACGCC
AGCAGTGGACACGGCGCTGGATGGAGCGTGGCTTTGCGGCACTGGAAACGCAGCTGGCGCGCGATGCGCAGACCGGGCGC
TTCTGCCACGGCGATGCACCGGGCCTGGCCGATTGCGTGCTGATTCCGCAGCTCTACAACGCGCGCCGGTTCGAGGTGGA
TCTGGCGCCATATCCGACCCTGCGGCGCATCGAGCAGGCCTGCCTGCAGTTGCCGGCCTTCGATGCGGCGCGCCCGGAGA
TGCAGGCCGACGCGGTGGCCTGA

Upstream 100 bases:

>100_bases
TTCGATGCCAGCGGCGCCAGCATCTTCGGTGCGATCGAACAGCGCGTCGAGCGGCAGCCGCTGCCATGACCTGCGGTGCA
GCGACGGCGGGCGGTCGCGC

Downstream 100 bases:

>100_bases
GGGACGCTGTCACAGCCCTCATCCGCCCTTCGGGCACCTTCTCCCGTCACACGGGAGAAGGGCAGGCGGGCACTCATCCG
GTTCGGGCTGTTGGCGCCAC

Product: maleylacetoacetate isomerase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSAALELFSYWRSSAAYRVRIGLGLKALDYIAQPVHLVRDGGEQHAPAYAQLNPQELVPTLRHGDVVIAQSLAILEYLEE
AFADTAALLPRAPAERARVRALAQLIACDVHPLNNLRVMQVLEREFALDGARRQQWTRRWMERGFAALETQLARDAQTGR
FCHGDAPGLADCVLIPQLYNARRFEVDLAPYPTLRRIEQACLQLPAFDAARPEMQADAVA

Sequences:

>Translated_220_residues
MSAALELFSYWRSSAAYRVRIGLGLKALDYIAQPVHLVRDGGEQHAPAYAQLNPQELVPTLRHGDVVIAQSLAILEYLEE
AFADTAALLPRAPAERARVRALAQLIACDVHPLNNLRVMQVLEREFALDGARRQQWTRRWMERGFAALETQLARDAQTGR
FCHGDAPGLADCVLIPQLYNARRFEVDLAPYPTLRRIEQACLQLPAFDAARPEMQADAVA
>Mature_219_residues
SAALELFSYWRSSAAYRVRIGLGLKALDYIAQPVHLVRDGGEQHAPAYAQLNPQELVPTLRHGDVVIAQSLAILEYLEEA
FADTAALLPRAPAERARVRALAQLIACDVHPLNNLRVMQVLEREFALDGARRQQWTRRWMERGFAALETQLARDAQTGRF
CHGDAPGLADCVLIPQLYNARRFEVDLAPYPTLRRIEQACLQLPAFDAARPEMQADAVA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=212, Percent_Identity=44.3396226415094, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI22202622, Length=161, Percent_Identity=43.4782608695652, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI194440732, Length=212, Percent_Identity=33.9622641509434, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17551302, Length=212, Percent_Identity=41.0377358490566, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17510461, Length=212, Percent_Identity=35.8490566037736, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17556142, Length=219, Percent_Identity=36.986301369863, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24645375, Length=212, Percent_Identity=41.5094339622642, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21355859, Length=212, Percent_Identity=41.5094339622642, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI45553325, Length=212, Percent_Identity=41.5094339622642, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21355857, Length=213, Percent_Identity=38.4976525821596, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 24598; Mature: 24467

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAALELFSYWRSSAAYRVRIGLGLKALDYIAQPVHLVRDGGEQHAPAYAQLNPQELVPT
CCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHH
LRHGDVVIAQSLAILEYLEEAFADTAALLPRAPAERARVRALAQLIACDVHPLNNLRVMQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
VLEREFALDGARRQQWTRRWMERGFAALETQLARDAQTGRFCHGDAPGLADCVLIPQLYN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
ARRFEVDLAPYPTLRRIEQACLQLPAFDAARPEMQADAVA
CEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAALELFSYWRSSAAYRVRIGLGLKALDYIAQPVHLVRDGGEQHAPAYAQLNPQELVPT
CHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHH
LRHGDVVIAQSLAILEYLEEAFADTAALLPRAPAERARVRALAQLIACDVHPLNNLRVMQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
VLEREFALDGARRQQWTRRWMERGFAALETQLARDAQTGRFCHGDAPGLADCVLIPQLYN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
ARRFEVDLAPYPTLRRIEQACLQLPAFDAARPEMQADAVA
CEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]