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The map label for this gene is aspC [H]

Identifier: 21244219

GI number: 21244219

Start: 4131666

End: 4132937

Strand: Direct

Name: aspC [H]

Synonym: XAC3494

Alternate gene names: 21244219

Gene position: 4131666-4132937 (Clockwise)

Preceding gene: 21244215

Following gene: 21244220

Centisome position: 79.83

GC content: 66.27

Gene sequence:

>1272_bases
ATGTCCACTGCCCCGCAAAAGCCGCTCGCCATCCGCGAGCGTCTGTCCGAAGTCCGCTACGAAATCCGGGGCGAGCTGGC
GCGACGAGCGCGGGAGCTGGAGGCGCAGGGCCGCAAGCTGATCAAGCTCAATATCGGTAACCCGGGTGCGTTCGGCTTCC
GTGCGCCGGAGCATCTGCAGCGCGCCATCGCCGACGACATGGGCCGCACCGATCCGTACACCCATCAGCAAGGCCTGCCG
GAAGCGCGCGAGGCGATCGCCACCGCATATGCGCGGCGCCAGCATCCGGATGCGCATCCGGACCGCATCTTCGTTGGCAA
CGGCGTCAGCGAACTGATCGATCTGTCGCTGCGTGCGCTGCTCAATCCCGGCGACGAAGTGCTGGTGCCCTCGCCCGACT
ATCCGCTGTGGTCGGCCGCGACCATCCTCAACGATGGTCGTCCCGTGTATTACCGCTGCGCCCCGGAAAACGGCTTCCAG
CCGGACCCAGTGGAGATCGAGACGCTGGTGTCCTCGCGCACCCGCGCCATCGTGCTGATCAATCCAAACAATCCCAGCGG
CGCCAGTTATTCGCGCGAACTGCTGGAGCGCATCGTGGCGATCGCCACCAAGCACAATCTGCTCTTGATGGTCGATGAGA
TCTACGACCAGGTGCTGTACGACGACGCGGCCTTCGTGCCGGTCGCGCCGCTGGCCGGCGCGCACCCGTGCATCACTTTC
AGCGGCCTGAGCAAGGTGCATCGCGCCTGCGGTTGGCGCGTGGGCTGGGCACTGCTGTCGGGCGACCAAGCGCGCATCAA
CGACTTGCGCAATGCGATGGACCTGCTCGGCGCCTTGCGCCTGTGCGCCAATGTACCAGGCCAGTACGCCATCGATGCGG
CCGTGAACGGGCCGGACACCATCTCGGCATTGTGCGCACCCGGCGGACGGCTGTACGAAACCCGCCGCGCGGTGATCGAG
GCCTGCGCGGCCAGCGAGCATCTGTCGCTGGTGGCACCGGCCGGTGCGCTGTATGCGTTCCCGGCAGTGGTGGGCGCGGC
GGCGCGCAACTTCGACGATCATGCGTTCGCCCTCGATCTGATGAACGAGGAAGGCGTGCTGGTGGTTCCCGGCTCCAGCT
TCAACGTGCCGTATCGCCATCATTTCCGCGTGACATTGATGCCGGAAGCCGGTGTGATGCGCGATGTGTTCGCGCGCATC
GACCGTGCACTGGCACGCCGCGCCGAAGCGGTCACCAAGGTGGTTCCACTCAAGCCACGCAGCGTGGCCTGA

Upstream 100 bases:

>100_bases
GGAGCGTGACGCCCCCTTGACATCGTTGCCGATGCAAGCATGTCCGCCTGTCATATTTCCGCTACCATGCCAAGCCTCAC
GCCTACAACCGGCCCGTCGC

Downstream 100 bases:

>100_bases
TGGCGGCGCCTGGCACGCCGCTGCGCTATTTGGCGCTCGGCGATTCGTACACCATCGGCGAAGGCGTTGCGCCTGCCCAG
CGTTGGCCATCGCAACTGGT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
EAREAIATAYARRQHPDAHPDRIFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIATKHNLLLMVDEIYDQVLYDDAAFVPVAPLAGAHPCITF
SGLSKVHRACGWRVGWALLSGDQARINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIE
ACAASEHLSLVAPAGALYAFPAVVGAAARNFDDHAFALDLMNEEGVLVVPGSSFNVPYRHHFRVTLMPEAGVMRDVFARI
DRALARRAEAVTKVVPLKPRSVA

Sequences:

>Translated_423_residues
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
EAREAIATAYARRQHPDAHPDRIFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIATKHNLLLMVDEIYDQVLYDDAAFVPVAPLAGAHPCITF
SGLSKVHRACGWRVGWALLSGDQARINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIE
ACAASEHLSLVAPAGALYAFPAVVGAAARNFDDHAFALDLMNEEGVLVVPGSSFNVPYRHHFRVTLMPEAGVMRDVFARI
DRALARRAEAVTKVVPLKPRSVA
>Mature_422_residues
STAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLPE
AREAIATAYARRQHPDAHPDRIFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQP
DPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIATKHNLLLMVDEIYDQVLYDDAAFVPVAPLAGAHPCITFS
GLSKVHRACGWRVGWALLSGDQARINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIEA
CAASEHLSLVAPAGALYAFPAVVGAAARNFDDHAFALDLMNEEGVLVVPGSSFNVPYRHHFRVTLMPEAGVMRDVFARID
RALARRAEAVTKVVPLKPRSVA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=29.0575916230367, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=28.3482142857143, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19263340, Length=466, Percent_Identity=26.1802575107296, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI95147551, Length=216, Percent_Identity=31.0185185185185, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI169881279, Length=216, Percent_Identity=31.0185185185185, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI215599424, Length=387, Percent_Identity=28.6821705426357, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=33.5664335664336, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI56713254, Length=213, Percent_Identity=28.169014084507, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI56713256, Length=213, Percent_Identity=28.169014084507, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=43.4673366834171, Blast_Score=344, Evalue=7e-96,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=25.9640102827763, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=25.2525252525253, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=27.8820375335121, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=27.4298056155508, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=24.7252747252747, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=24.7252747252747, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=272, Percent_Identity=24.2647058823529, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=296, Percent_Identity=26.3513513513513, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=457, Percent_Identity=25.8205689277899, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=461, Percent_Identity=25.3796095444685, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=239, Percent_Identity=28.4518828451883, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322075, Length=188, Percent_Identity=30.3191489361702, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=27.6762402088773, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24641770, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641760, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641768, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641766, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641764, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551451, Length=456, Percent_Identity=27.4122807017544, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573069, Length=232, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646114, Length=232, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573067, Length=232, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573065, Length=232, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 46136; Mature: 46005

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPEAREAIATAYARRQHPDAHPDRIFVGNGVSELIDLSLRAL
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDPVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEE
NPNNPSGASYSRELLERIVAIATKHNLLLMVDEIYDQVLYDDAAFVPVAPLAGAHPCITF
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEH
SGLSKVHRACGWRVGWALLSGDQARINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ISALCAPGGRLYETRRAVIEACAASEHLSLVAPAGALYAFPAVVGAAARNFDDHAFALDL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEE
MNEEGVLVVPGSSFNVPYRHHFRVTLMPEAGVMRDVFARIDRALARRAEAVTKVVPLKPR
ECCCCEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVA
CCC
>Mature Secondary Structure 
STAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPEAREAIATAYARRQHPDAHPDRIFVGNGVSELIDLSLRAL
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDPVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEE
NPNNPSGASYSRELLERIVAIATKHNLLLMVDEIYDQVLYDDAAFVPVAPLAGAHPCITF
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEH
SGLSKVHRACGWRVGWALLSGDQARINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ISALCAPGGRLYETRRAVIEACAASEHLSLVAPAGALYAFPAVVGAAARNFDDHAFALDL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEE
MNEEGVLVVPGSSFNVPYRHHFRVTLMPEAGVMRDVFARIDRALARRAEAVTKVVPLKPR
ECCCCEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]