Click here to switch to the map view.

The map label for this gene is lytH [H]

Identifier: 21244093

GI number: 21244093

Start: 3967496

End: 3968215

Strand: Direct

Name: lytH [H]

Synonym: XAC3368

Alternate gene names: 21244093

Gene position: 3967496-3968215 (Clockwise)

Preceding gene: 77748712

Following gene: 21244096

Centisome position: 76.66

GC content: 64.86

Gene sequence:

>720_bases
ATGAAACTGCTGATGACTTTGGTGGTGGGCGTCGTGTTGGGTGCGGCCGGCTATTGGTGGCTGGAACGCACCGCGCCGGA
AGCAAAAGTAGAGCCGTCATCCAGCGCTGCTCCCGTCGCAACAGACCGCAGCTCAGCGAGTGCCGCGCCGATGGCAGCCC
CTGCAGCGACCGCCGCGGCAGCACCGATGGCTGCCTCGGCACCACTGGCCGATGCCGCGCCCGCCGGCATGCCCGTAGCA
ACGACGCCAGCGCAGTCGCCTGCCGCTGCGGCACCGGGCAGCGGCTTGCTGATCCCGGTACAGGGCATCAGCGCCAGCCA
GTTGCAAGACACCTTCACCGATGCGCGCAGCGAAGGCCGCGTGCACGATGCCATCGACATCCTCGCTCCCACCGGCACAC
CGGTCGTGGCAGTTGCCGACGGCACGGTGGAGAAACTGTTCACCAGCGACCGGGGCGGCCTGACCGTCTACCAGTTCGAG
CCCAGCGGCAAATACTGCTATTACTACGCGCACCTGGAGCGCTATGCCGACGGCTTGGCGGAGAAACAATCGATCAAGCG
CGGCCAGGTCATTGGCTATGTCGGCAGCACCGGCAACGCCAATCCCGCCGCACCGCATCTGCATTTCGAGATCCACCGCC
TGGGACCTGAAAAACAATGGTGGAAGGGGGACGCATTGAATCCTTACCCCGTCTTGCACGGCGATCAGATGTTGCAGTGA

Upstream 100 bases:

>100_bases
AGACCGAATCGCATGGCTGCGTGCGGCTGACCAACTGGGACGTGGTCGCCCTCGCCAGCGTGGTCGGCCCGTCGGTGCCG
GTGGTGATGCAGGAGTAAAC

Downstream 100 bases:

>100_bases
CAGCGAGGCAAGTTCCGCACCAACATCTCTTCTTTCAGCAGATCTGGCAGCCCGATACAGACTTATTCAGCACCTCGCCT
CAACACTAAAGCGCCCGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKLLMTLVVGVVLGAAGYWWLERTAPEAKVEPSSSAAPVATDRSSASAAPMAAPAATAAAAPMAASAPLADAAPAGMPVA
TTPAQSPAAAAPGSGLLIPVQGISASQLQDTFTDARSEGRVHDAIDILAPTGTPVVAVADGTVEKLFTSDRGGLTVYQFE
PSGKYCYYYAHLERYADGLAEKQSIKRGQVIGYVGSTGNANPAAPHLHFEIHRLGPEKQWWKGDALNPYPVLHGDQMLQ

Sequences:

>Translated_239_residues
MKLLMTLVVGVVLGAAGYWWLERTAPEAKVEPSSSAAPVATDRSSASAAPMAAPAATAAAAPMAASAPLADAAPAGMPVA
TTPAQSPAAAAPGSGLLIPVQGISASQLQDTFTDARSEGRVHDAIDILAPTGTPVVAVADGTVEKLFTSDRGGLTVYQFE
PSGKYCYYYAHLERYADGLAEKQSIKRGQVIGYVGSTGNANPAAPHLHFEIHRLGPEKQWWKGDALNPYPVLHGDQMLQ
>Mature_239_residues
MKLLMTLVVGVVLGAAGYWWLERTAPEAKVEPSSSAAPVATDRSSASAAPMAAPAATAAAAPMAASAPLADAAPAGMPVA
TTPAQSPAAAAPGSGLLIPVQGISASQLQDTFTDARSEGRVHDAIDILAPTGTPVVAVADGTVEKLFTSDRGGLTVYQFE
PSGKYCYYYAHLERYADGLAEKQSIKRGQVIGYVGSTGNANPAAPHLHFEIHRLGPEKQWWKGDALNPYPVLHGDQMLQ

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 24790; Mature: 24790

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLMTLVVGVVLGAAGYWWLERTAPEAKVEPSSSAAPVATDRSSASAAPMAAPAATAAA
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
APMAASAPLADAAPAGMPVATTPAQSPAAAAPGSGLLIPVQGISASQLQDTFTDARSEGR
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
VHDAIDILAPTGTPVVAVADGTVEKLFTSDRGGLTVYQFEPSGKYCYYYAHLERYADGLA
CHHHHEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHH
EKQSIKRGQVIGYVGSTGNANPAAPHLHFEIHRLGPEKQWWKGDALNPYPVLHGDQMLQ
HHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCHHHCC
>Mature Secondary Structure
MKLLMTLVVGVVLGAAGYWWLERTAPEAKVEPSSSAAPVATDRSSASAAPMAAPAATAAA
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
APMAASAPLADAAPAGMPVATTPAQSPAAAAPGSGLLIPVQGISASQLQDTFTDARSEGR
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
VHDAIDILAPTGTPVVAVADGTVEKLFTSDRGGLTVYQFEPSGKYCYYYAHLERYADGLA
CHHHHEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHH
EKQSIKRGQVIGYVGSTGNANPAAPHLHFEIHRLGPEKQWWKGDALNPYPVLHGDQMLQ
HHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]