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The map label for this gene is ycgM [C]

Identifier: 21244032

GI number: 21244032

Start: 3885289

End: 3886002

Strand: Direct

Name: ycgM [C]

Synonym: XAC3307

Alternate gene names: 21244032

Gene position: 3885289-3886002 (Clockwise)

Preceding gene: 21244031

Following gene: 21244033

Centisome position: 75.07

GC content: 65.13

Gene sequence:

>714_bases
ATGACCCACGATGTGATTCCCGCCGCCGATGTTCCGCGCATTCCTGTGGTGGGTGGTGGCAGTTTTCCGGTGCATCGCAT
CTACTGCGTGGGGCGCAACTTTGCCGACCATGCGCGCGAGATGGGCGCCACCGCACCAGCCTCCAAGGCCGAGCGTGGCC
AGCCGACTTTTTTCATGAAGCCTGCCGATGCCATCGTGGTCGGCCACGGCGACCACATCCCCTACCCGCCTGGCACCAAG
GAACTGCACCATGAAGTGGAACTGGTGGTGGCGCTGGGCAGCGATGCGCCGGCCGGCGAGTTGCCGGTGGCACAGGCCGA
ACGCCTGATCTACGGCTACGGCGTGGGCCTGGATCTGACCCGTCGCGACTTGCAGGCCGCTGCCAAGGCCAAGGGCTTGC
CGTGGGATATCGCGAAGGGCTTCGATCACTCCGCACCGATCAGCGAGCTGGTGCATGCCGGCGAAGTCGGCGCGCTGGAG
GCGCTGAATCTGTCGCTGGAGGTCAACGGCCAGGTCCGTCAGCAGTCGTTGCTGGATCAAATGATCTGGAACGTGCCGGA
GATCCTGCACGAGCTTTCCAAACTGTATGCACTGCGCGCAGGCGATCTGATTTTCATGGGCACGCCGGCCGGCGTCGGCC
CGTTGCTGCCAGGCGACCAGTTCAGTGCGCGCCTGGAGAACGTCGCCGAGCGCCACGGCATCATCGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCCAGCCCGGCCGTGTCGTGCGCTGGATGCACGCGTCATGGTTCCGTCGTACACAGGCGAACCGCTAGACTCACCTGCC
CGTATGTTGAGGATGCGCGC

Downstream 100 bases:

>100_bases
CATCGCACCGGCTACGATCGGGCTGCGGCAGTTGGTCCGCGACCGCAGTTGGAGTGCACTATGGGAATGGTCAGCGAATT
CAAGCAATTCGCAATGCGCG

Product: fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTHDVIPAADVPRIPVVGGGSFPVHRIYCVGRNFADHAREMGATAPASKAERGQPTFFMKPADAIVVGHGDHIPYPPGTK
ELHHEVELVVALGSDAPAGELPVAQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIAKGFDHSAPISELVHAGEVGALE
ALNLSLEVNGQVRQQSLLDQMIWNVPEILHELSKLYALRAGDLIFMGTPAGVGPLLPGDQFSARLENVAERHGIIAG

Sequences:

>Translated_237_residues
MTHDVIPAADVPRIPVVGGGSFPVHRIYCVGRNFADHAREMGATAPASKAERGQPTFFMKPADAIVVGHGDHIPYPPGTK
ELHHEVELVVALGSDAPAGELPVAQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIAKGFDHSAPISELVHAGEVGALE
ALNLSLEVNGQVRQQSLLDQMIWNVPEILHELSKLYALRAGDLIFMGTPAGVGPLLPGDQFSARLENVAERHGIIAG
>Mature_236_residues
THDVIPAADVPRIPVVGGGSFPVHRIYCVGRNFADHAREMGATAPASKAERGQPTFFMKPADAIVVGHGDHIPYPPGTKE
LHHEVELVVALGSDAPAGELPVAQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIAKGFDHSAPISELVHAGEVGALEA
LNLSLEVNGQVRQQSLLDQMIWNVPEILHELSKLYALRAGDLIFMGTPAGVGPLLPGDQFSARLENVAERHGIIAG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=210, Percent_Identity=40, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=41.6243654822335, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=41.6243654822335, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI156231349, Length=211, Percent_Identity=29.8578199052133, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40786394, Length=211, Percent_Identity=29.8578199052133, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1787428, Length=206, Percent_Identity=38.8349514563107, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=37.1134020618557, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=230, Percent_Identity=33.0434782608696, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28571789, Length=177, Percent_Identity=33.8983050847458, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28572127, Length=189, Percent_Identity=31.7460317460317, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24663695, Length=236, Percent_Identity=26.271186440678, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25228; Mature: 25097

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDVIPAADVPRIPVVGGGSFPVHRIYCVGRNFADHAREMGATAPASKAERGQPTFFMK
CCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEEEEC
PADAIVVGHGDHIPYPPGTKELHHEVELVVALGSDAPAGELPVAQAERLIYGYGVGLDLT
CCCEEEEECCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCHHHHHHEEEEECCCCCHH
RRDLQAAAKAKGLPWDIAKGFDHSAPISELVHAGEVGALEALNLSLEVNGQVRQQSLLDQ
HHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHH
MIWNVPEILHELSKLYALRAGDLIFMGTPAGVGPLLPGDQFSARLENVAERHGIIAG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
THDVIPAADVPRIPVVGGGSFPVHRIYCVGRNFADHAREMGATAPASKAERGQPTFFMK
CCCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEEEEC
PADAIVVGHGDHIPYPPGTKELHHEVELVVALGSDAPAGELPVAQAERLIYGYGVGLDLT
CCCEEEEECCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCHHHHHHEEEEECCCCCHH
RRDLQAAAKAKGLPWDIAKGFDHSAPISELVHAGEVGALEALNLSLEVNGQVRQQSLLDQ
HHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHH
MIWNVPEILHELSKLYALRAGDLIFMGTPAGVGPLLPGDQFSARLENVAERHGIIAG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]