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The map label for this gene is ostB [H]

Identifier: 21243935

GI number: 21243935

Start: 3779046

End: 3779804

Strand: Direct

Name: ostB [H]

Synonym: XAC3209

Alternate gene names: 21243935

Gene position: 3779046-3779804 (Clockwise)

Preceding gene: 21243934

Following gene: 21243936

Centisome position: 73.02

GC content: 69.96

Gene sequence:

>759_bases
ATGGCAGACGCGCAATCCCCCCTACCGTCGCCGCCATTGCTGGACGATGCCTGTGCATTGTTTCTGGACGTGGACGGCAC
CCTCATCGACTTTGCCGACCGCCCCGAGGCGGTGCAGCTATTGCCCGACGTGCGCGAGGCCATCGGCCTGCTGAGCGAGC
GCCTCAAGGGCGCCGTCGCACTGGTCAGCGGCCGGCCACTCGCCCAGCTGGATGCCCTGTTCGCTCCCTTGCTGCTGCCG
GCCGCCGGTCTGCACGGGCATGAGCTGCGCAGCGATCTCGCGGCACGCGCGGCAATGCCCCAAGACACGTCCCAGTGGCT
GCACGGCCTGCATCAACGCGCCGCGGCGCTGACGCACCACCACCCCGGCGTGCTGGTCGAAGACAAGGGCGCCAGCGTGG
CGCTGCACTGGCGCGCCCGGCCGCAGGCCGGCCCCGAGGTGCTCGCCTTCGCGCAGCAGGAAATCGCACAGCTTTCCGGC
TATCGCCTGCAGCCTGGCGACCACGTGGTGGAATTCGTTCCCGAAGGCAGCAACAAGGGTCTGGCGGTCGAGCAGCTGAT
GCAGCACGGCACCTTCGCCGGTCGCACGCCGGTGTTCGTCGGCGACGACCTTACCGACGAATTCGGCTTCGACGCCGCCA
ACCGGCTCGGCGGCTGGAGCGTGCTCGTCGGCGATCGCGCGCAGACCAGCGCGCGCTTTCGCGTCGGCGGCACCCCCGAC
GTACACGCGTGGTTGCAACGCAACGCACGCAGCCGCTGA

Upstream 100 bases:

>100_bases
CCTTCTCTCCCATGAAGGAGGACAATGCCCCAGCGGGAGAAGGAGCAATCCCCGCCGTTCCATAACCTGAATCTCACACC
CCATTGCGCACACTAGCGCA

Downstream 100 bases:

>100_bases
GCACAGCGCACCTGCTCTCATTCACTTCAACAGGATCGTTTGCACTCCATGACCGAGCCAAACCTGGATCTGGGCGTCAT
CGGCAACTGCAGTTTCGGTG

Product: trehalose-6-phosphate phosphatase

Products: NA

Alternate protein names: TPP; Osmoregulatory trehalose synthesis protein B; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MADAQSPLPSPPLLDDACALFLDVDGTLIDFADRPEAVQLLPDVREAIGLLSERLKGAVALVSGRPLAQLDALFAPLLLP
AAGLHGHELRSDLAARAAMPQDTSQWLHGLHQRAAALTHHHPGVLVEDKGASVALHWRARPQAGPEVLAFAQQEIAQLSG
YRLQPGDHVVEFVPEGSNKGLAVEQLMQHGTFAGRTPVFVGDDLTDEFGFDAANRLGGWSVLVGDRAQTSARFRVGGTPD
VHAWLQRNARSR

Sequences:

>Translated_252_residues
MADAQSPLPSPPLLDDACALFLDVDGTLIDFADRPEAVQLLPDVREAIGLLSERLKGAVALVSGRPLAQLDALFAPLLLP
AAGLHGHELRSDLAARAAMPQDTSQWLHGLHQRAAALTHHHPGVLVEDKGASVALHWRARPQAGPEVLAFAQQEIAQLSG
YRLQPGDHVVEFVPEGSNKGLAVEQLMQHGTFAGRTPVFVGDDLTDEFGFDAANRLGGWSVLVGDRAQTSARFRVGGTPD
VHAWLQRNARSR
>Mature_251_residues
ADAQSPLPSPPLLDDACALFLDVDGTLIDFADRPEAVQLLPDVREAIGLLSERLKGAVALVSGRPLAQLDALFAPLLLPA
AGLHGHELRSDLAARAAMPQDTSQWLHGLHQRAAALTHHHPGVLVEDKGASVALHWRARPQAGPEVLAFAQQEIAQLSGY
RLQPGDHVVEFVPEGSNKGLAVEQLMQHGTFAGRTPVFVGDDLTDEFGFDAANRLGGWSVLVGDRAQTSARFRVGGTPDV
HAWLQRNARSR

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=247, Percent_Identity=40.4858299595142, Blast_Score=164, Evalue=7e-42,
Organism=Drosophila melanogaster, GI221473368, Length=247, Percent_Identity=25.5060728744939, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129307, Length=247, Percent_Identity=25.5060728744939, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582490, Length=247, Percent_Identity=25.5060728744939, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 27030; Mature: 26899

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAQSPLPSPPLLDDACALFLDVDGTLIDFADRPEAVQLLPDVREAIGLLSERLKGAVA
CCCCCCCCCCCCCHHHHHEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCEEE
LVSGRPLAQLDALFAPLLLPAAGLHGHELRSDLAARAAMPQDTSQWLHGLHQRAAALTHH
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
HPGVLVEDKGASVALHWRARPQAGPEVLAFAQQEIAQLSGYRLQPGDHVVEFVPEGSNKG
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
LAVEQLMQHGTFAGRTPVFVGDDLTDEFGFDAANRLGGWSVLVGDRAQTSARFRVGGTPD
HHHHHHHHCCCCCCCCCEEECCCCCHHHCCCHHHHCCCEEEEECCCCCCCCEEECCCCCH
VHAWLQRNARSR
HHHHHHHHCCCC
>Mature Secondary Structure 
ADAQSPLPSPPLLDDACALFLDVDGTLIDFADRPEAVQLLPDVREAIGLLSERLKGAVA
CCCCCCCCCCCCHHHHHEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCEEE
LVSGRPLAQLDALFAPLLLPAAGLHGHELRSDLAARAAMPQDTSQWLHGLHQRAAALTHH
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
HPGVLVEDKGASVALHWRARPQAGPEVLAFAQQEIAQLSGYRLQPGDHVVEFVPEGSNKG
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
LAVEQLMQHGTFAGRTPVFVGDDLTDEFGFDAANRLGGWSVLVGDRAQTSARFRVGGTPD
HHHHHHHHCCCCCCCCCEEECCCCCHHHCCCHHHHCCCEEEEECCCCCCCCEEECCCCCH
VHAWLQRNARSR
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045430; 9097040; 9278503 [H]