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The map label for this gene is prpL [H]

Identifier: 21243719

GI number: 21243719

Start: 3498258

End: 3499655

Strand: Direct

Name: prpL [H]

Synonym: XAC2992

Alternate gene names: 21243719

Gene position: 3498258-3499655 (Clockwise)

Preceding gene: 21243718

Following gene: 21243720

Centisome position: 67.59

GC content: 63.16

Gene sequence:

>1398_bases
ATGAATCGCAAGAACGCGATGTATCTGGCGTTGTTTTCCGCTATTTCCGGCACCGCAGCGGCCGCTCCACCGACCGAGAT
GGATGCAGCGCCGGTCACCACCGCGCCGCAGGCGGCCAAGCTTGGTGCGGCAACGTTGCAATCGGCGAGTTTACGCGGCG
GCGTTCTGCCCACGCGCGTGGTGCAACTTGCCGCACCCACCAGTGCCGAGATCGGCCGTGTGCGCGAGCGTCGCATTGCG
CAGGTCAAGCAGGGGCAGCCGTTGCAGATCGGTTTTTCGCGTGCAGTCGCACAGCCGACGGTGAACCTGTCCAGGCTCGA
TTGGCAGATGGCTCCCGATGGCTCGCGCGTGGCCAGCCTCAAAGTCAGTTCCGCACAGGCGGCATCGTTGCGTGCATCGC
TGATCCTGCGTGGCGCCGGTGCAACGCCTGGCGACCCGTCCAAGGCGACGCTGCGCTTTGCCGGCAACGATGGTCGCGTG
TTCGAGCAATCCGGCGCCAGCTTTGCTGCCAGCGGCAACGATATCGGGTGGTCGCCGACGGTGAGTGGCGAGGACCTGCT
GGTCGAACTGTCGCTGCCGGCCGGGCTGTATCCGGAGAACTTCAGCCTCAGCATCCCGCAGCTGTCGCATCTGGATATCA
GCCCCACTGCCAGCCCGCGCGACATGATGACCATTGCCATCGGCGAAAGCGATTCCTGTCAGAACGATATCGTCTGCCGT
GCCAACCCCACGACCGGCTTTACCAGCGCCGCAAAGGCAGTGGCGCGCATGGTGTTCACCACCAGCCAGGGCTCGTTCCT
GTGCACCGGCACCCTGCTCAACAATACCAATTCGCCCAAACGCAACCTGTTCTGGACTGCGGCGCATTGCATCAGCACGC
AGACCGTGGCCAACACGCTGCAGACATACTGGTTCTACGATGCGGCCAGCTGCAATGGCAGTACGGTCAGCTCGCAGGCA
ACCACACTGACGGGCGGCGCATTCCTGCGGCATGCCAACACCACGCGCGACACCGCATTGCTGGAGCTGAAGACCGCACC
GCCAAGCGGCGCATTCTACGCAGCGTGGAATAGCGCGGCGATCGGTTCTACCGGTACTTCGATTGTCGGCATCCATCACC
CATCGGGCGACGTCAAGAAGTATTCGCTGGGTACGGTGAATGCGCTGAGCAGCTCCATCGATGGCAAGAGCCCGCTCTAT
CGTGTGGTCTGGAACGACGGTGTCACCGAAGGCGGCTCGTCCGGCTCGGGCCTGTTCACCATCGCCAGCGGTGGCGCCTA
CCAGCTGCGTGGCGGCCTGTATGGCGGCTATTCGTTCTGCAGCGCGCAGACCGATCCGGATTACTACTCGCGCTTCTCGG
ACGTGTATTCCACCATTTCTACCTACTTCGGCCAGTAA

Upstream 100 bases:

>100_bases
CATCTTTGAACTTCCGCTAGGCTCGTTCGGCGCCAACGATGGCGCCCGCTTGTTGCAGCCCCCGCTGCAGCCTGACGATC
CCTGACGAGAAGGACTACCC

Downstream 100 bases:

>100_bases
GCGGCCAAGCCGCGTGGCAGGCGATGTTGCGCCTGCCACGCTTGATCGCGCTTGTTCCGGCAATCCGTTTGCCGGGCGAG
GCGTCTACGGTTCAGCGATG

Product: endoproteinase ArgC

Products: NA

Alternate protein names: Protease IV; pvdS-regulated endoprotease [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNRKNAMYLALFSAISGTAAAAPPTEMDAAPVTTAPQAAKLGAATLQSASLRGGVLPTRVVQLAAPTSAEIGRVRERRIA
QVKQGQPLQIGFSRAVAQPTVNLSRLDWQMAPDGSRVASLKVSSAQAASLRASLILRGAGATPGDPSKATLRFAGNDGRV
FEQSGASFAASGNDIGWSPTVSGEDLLVELSLPAGLYPENFSLSIPQLSHLDISPTASPRDMMTIAIGESDSCQNDIVCR
ANPTTGFTSAAKAVARMVFTTSQGSFLCTGTLLNNTNSPKRNLFWTAAHCISTQTVANTLQTYWFYDAASCNGSTVSSQA
TTLTGGAFLRHANTTRDTALLELKTAPPSGAFYAAWNSAAIGSTGTSIVGIHHPSGDVKKYSLGTVNALSSSIDGKSPLY
RVVWNDGVTEGGSSGSGLFTIASGGAYQLRGGLYGGYSFCSAQTDPDYYSRFSDVYSTISTYFGQ

Sequences:

>Translated_465_residues
MNRKNAMYLALFSAISGTAAAAPPTEMDAAPVTTAPQAAKLGAATLQSASLRGGVLPTRVVQLAAPTSAEIGRVRERRIA
QVKQGQPLQIGFSRAVAQPTVNLSRLDWQMAPDGSRVASLKVSSAQAASLRASLILRGAGATPGDPSKATLRFAGNDGRV
FEQSGASFAASGNDIGWSPTVSGEDLLVELSLPAGLYPENFSLSIPQLSHLDISPTASPRDMMTIAIGESDSCQNDIVCR
ANPTTGFTSAAKAVARMVFTTSQGSFLCTGTLLNNTNSPKRNLFWTAAHCISTQTVANTLQTYWFYDAASCNGSTVSSQA
TTLTGGAFLRHANTTRDTALLELKTAPPSGAFYAAWNSAAIGSTGTSIVGIHHPSGDVKKYSLGTVNALSSSIDGKSPLY
RVVWNDGVTEGGSSGSGLFTIASGGAYQLRGGLYGGYSFCSAQTDPDYYSRFSDVYSTISTYFGQ
>Mature_465_residues
MNRKNAMYLALFSAISGTAAAAPPTEMDAAPVTTAPQAAKLGAATLQSASLRGGVLPTRVVQLAAPTSAEIGRVRERRIA
QVKQGQPLQIGFSRAVAQPTVNLSRLDWQMAPDGSRVASLKVSSAQAASLRASLILRGAGATPGDPSKATLRFAGNDGRV
FEQSGASFAASGNDIGWSPTVSGEDLLVELSLPAGLYPENFSLSIPQLSHLDISPTASPRDMMTIAIGESDSCQNDIVCR
ANPTTGFTSAAKAVARMVFTTSQGSFLCTGTLLNNTNSPKRNLFWTAAHCISTQTVANTLQTYWFYDAASCNGSTVSSQA
TTLTGGAFLRHANTTRDTALLELKTAPPSGAFYAAWNSAAIGSTGTSIVGIHHPSGDVKKYSLGTVNALSSSIDGKSPLY
RVVWNDGVTEGGSSGSGLFTIASGGAYQLRGGLYGGYSFCSAQTDPDYYSRFSDVYSTISTYFGQ

Specific function: Lysine-specific endoprotease. Involved in corneal virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003 [H]

Pfam domain/function: NA

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 48470; Mature: 48470

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKNAMYLALFSAISGTAAAAPPTEMDAAPVTTAPQAAKLGAATLQSASLRGGVLPTRV
CCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VQLAAPTSAEIGRVRERRIAQVKQGQPLQIGFSRAVAQPTVNLSRLDWQMAPDGSRVASL
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHEEEEECCCCCEEEEE
KVSSAQAASLRASLILRGAGATPGDPSKATLRFAGNDGRVFEQSGASFAASGNDIGWSPT
EECCCHHHHEEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCC
VSGEDLLVELSLPAGLYPENFSLSIPQLSHLDISPTASPRDMMTIAIGESDSCQNDIVCR
CCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
ANPTTGFTSAAKAVARMVFTTSQGSFLCTGTLLNNTNSPKRNLFWTAAHCISTQTVANTL
ECCCCCHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHH
QTYWFYDAASCNGSTVSSQATTLTGGAFLRHANTTRDTALLELKTAPPSGAFYAAWNSAA
HHHEEEEECCCCCCEECCCCEEEECCCEEEECCCCCCEEEEEEECCCCCCCEEEEECCCC
IGSTGTSIVGIHHPSGDVKKYSLGTVNALSSSIDGKSPLYRVVWNDGVTEGGSSGSGLFT
CCCCCCEEEEEECCCCCCEEEECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEE
IASGGAYQLRGGLYGGYSFCSAQTDPDYYSRFSDVYSTISTYFGQ
EECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRKNAMYLALFSAISGTAAAAPPTEMDAAPVTTAPQAAKLGAATLQSASLRGGVLPTRV
CCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VQLAAPTSAEIGRVRERRIAQVKQGQPLQIGFSRAVAQPTVNLSRLDWQMAPDGSRVASL
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHEEEEECCCCCEEEEE
KVSSAQAASLRASLILRGAGATPGDPSKATLRFAGNDGRVFEQSGASFAASGNDIGWSPT
EECCCHHHHEEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCC
VSGEDLLVELSLPAGLYPENFSLSIPQLSHLDISPTASPRDMMTIAIGESDSCQNDIVCR
CCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
ANPTTGFTSAAKAVARMVFTTSQGSFLCTGTLLNNTNSPKRNLFWTAAHCISTQTVANTL
ECCCCCHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHH
QTYWFYDAASCNGSTVSSQATTLTGGAFLRHANTTRDTALLELKTAPPSGAFYAAWNSAA
HHHEEEEECCCCCCEECCCCEEEECCCEEEECCCCCCEEEEEEECCCCCCCEEEEECCCC
IGSTGTSIVGIHHPSGDVKKYSLGTVNALSSSIDGKSPLYRVVWNDGVTEGGSSGSGLFT
CCCCCCEEEEEECCCCCCEEEECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEE
IASGGAYQLRGGLYGGYSFCSAQTDPDYYSRFSDVYSTISTYFGQ
EECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12419815; 10984043 [H]