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The map label for this gene is lptA [H]

Identifier: 21243697

GI number: 21243697

Start: 3472916

End: 3473476

Strand: Direct

Name: lptA [H]

Synonym: XAC2970

Alternate gene names: 21243697

Gene position: 3472916-3473476 (Clockwise)

Preceding gene: 21243696

Following gene: 21243698

Centisome position: 67.1

GC content: 62.21

Gene sequence:

>561_bases
ATGAACCGAATGCTGCCCGCTAAACTGGCGTTTGCCGCACTGCTGCTGCCTGCGTTGGCAATGGCCAAGACCAGCGATCG
CAACCAGCCGATGGCGATCGACTCCAATGCCAACGATTGCAACATGCTCGACGACAGCGGCAAGTGCCGTTTCAGCGGCA
ATGTGGTGATCACCCAGGGCACGCTGGAAATCCACGCCGACACCGCCGACATCTTCCAGAAGAACGGCCAGACCGATCGC
GTGGTGCTCAACGGCAAGCAGGCCACGCTCAAGCAGGAGATGGACGACGGCGCCACGATGCACGGCCAGGCCGACAACAT
CGAATACAAGGTCGCCGATGAGATCATCATCCTGACCGGCAATTACAAGGTCGATTCGCCCAAGGGCACCAACGCCGGCC
AGCGCATGGTCTACAACACCAAGACCGGCAACATGCAGAGCGGCGGCGATGGCAGCCGGGTGCGCACCATCATCCAGCCG
AAAAATGCGGCGCCTGCCGCTGCAACGCCTGCGGCGACACCGGCCGCCAAGCCCGCTGCCAAGCCGCAGGGGAAGAAGTA
A

Upstream 100 bases:

>100_bases
GTGACCATGACCCGCCCGGGTATCATGCAGAGCGGCGTCGGCTTCGAAGCCGACCTCAAATCACGCCAGTACAAGCTCCT
CTCTCAGGTCAAGACCCGCT

Downstream 100 bases:

>100_bases
TGCTGGTCGCCACCGGTCTGCGCAAGAAGTACAAGCAACGCGAAGTGGTCAAGGAGTTCGGCCTCACGCTCGAGTCCGGC
GAAGTGGTCGGTCTGCTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMAIDSNANDCNMLDDSGKCRFSGNVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGATMHGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KNAAPAAATPAATPAAKPAAKPQGKK

Sequences:

>Translated_186_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMAIDSNANDCNMLDDSGKCRFSGNVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGATMHGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KNAAPAAATPAATPAAKPAAKPQGKK
>Mature_186_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMAIDSNANDCNMLDDSGKCRFSGNVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGATMHGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KNAAPAAATPAATPAAKPAAKPQGKK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=161, Percent_Identity=33.5403726708075, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19702; Mature: 19702

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMAIDSNANDCNMLDDSGKCRFSGNVVITQG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCEEEECCEEEEEC
TLEIHADTADIFQKNGQTDRVVLNGKQATLKQEMDDGATMHGQADNIEYKVADEIIILTG
EEEEECCHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEECCCCCCEEEEEECEEEEEEC
NYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQPKNAAPAAATPAATPAAKPAA
CEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
KPQGKK
CCCCCC
>Mature Secondary Structure
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMAIDSNANDCNMLDDSGKCRFSGNVVITQG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCEEEECCEEEEEC
TLEIHADTADIFQKNGQTDRVVLNGKQATLKQEMDDGATMHGQADNIEYKVADEIIILTG
EEEEECCHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEECCCCCCEEEEEECEEEEEEC
NYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQPKNAAPAAATPAATPAAKPAA
CEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
KPQGKK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]