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The map label for this gene is pfpI [H]

Identifier: 21243659

GI number: 21243659

Start: 3437472

End: 3438014

Strand: Reverse

Name: pfpI [H]

Synonym: XAC2932

Alternate gene names: 21243659

Gene position: 3438014-3437472 (Counterclockwise)

Preceding gene: 21243660

Following gene: 21243651

Centisome position: 66.43

GC content: 61.51

Gene sequence:

>543_bases
ATGTCTTATTCGCTTACAGGCAAGACGGTTGCCGTGCTGGCCACCGATGGCTTCGAGCAATCCGAACTGACCGAGCCCAA
GCGCCTGCTGGAAAGTTGGGGTGCCAAGGTCGAGGTGATCGCGCCAGGCGACAGCGCACAGATTCGCGCCTGGAATCACA
CAGATTGGGGCGATTCGGTAGCGGTCGATCGGCAGCTGGAACAGGCAACAGCCGAATCCTACGACGCACTGGTATTGCCT
GGCGGGGTGCTCAATCCCGATACGCTGCGCACCGATAAGCAGGCAATCGCGTTCATTCGCGCGTTTTCGACCGCACAAAA
ACCGGTGGCGGCGATCTGCCATGGGCCGTGGCTGTTGCTCGAAAGCGACTTGGTCCGTGACCGCGAGGTCACCTCATGGC
CGTCGGTCAAGACGGACCTGATCAATGCCGGCGCGCGCTGGCAGGATGCCGAAGTGGTGGTCGATGGCCAGCTGATTACC
AGCCGCAAACCGGACGACATTCCTGCATTCGCCGCGGCAGTGGCCAAGGCCTTGGCTGCATAG

Upstream 100 bases:

>100_bases
TGAAGGTGGCGTCATGCGCTGACGCCACGCACACATCGGTTCACGGGTGCGCAACGGCGCGCTTTCTAGGTTTGGGCTTC
TTTTTTAAGAGGAGCCCCGC

Downstream 100 bases:

>100_bases
GCTCTTCACTGGCCAGTGTCAGCTCGAAACAAGAAGGCCCGGCGCAGGTGCGTCGGGCCTTTCCATCTGGAGTGGTGCGT
GGGTTACGCCATCGACGCCA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSYSLTGKTVAVLATDGFEQSELTEPKRLLESWGAKVEVIAPGDSAQIRAWNHTDWGDSVAVDRQLEQATAESYDALVLP
GGVLNPDTLRTDKQAIAFIRAFSTAQKPVAAICHGPWLLLESDLVRDREVTSWPSVKTDLINAGARWQDAEVVVDGQLIT
SRKPDDIPAFAAAVAKALAA

Sequences:

>Translated_180_residues
MSYSLTGKTVAVLATDGFEQSELTEPKRLLESWGAKVEVIAPGDSAQIRAWNHTDWGDSVAVDRQLEQATAESYDALVLP
GGVLNPDTLRTDKQAIAFIRAFSTAQKPVAAICHGPWLLLESDLVRDREVTSWPSVKTDLINAGARWQDAEVVVDGQLIT
SRKPDDIPAFAAAVAKALAA
>Mature_179_residues
SYSLTGKTVAVLATDGFEQSELTEPKRLLESWGAKVEVIAPGDSAQIRAWNHTDWGDSVAVDRQLEQATAESYDALVLPG
GVLNPDTLRTDKQAIAFIRAFSTAQKPVAAICHGPWLLLESDLVRDREVTSWPSVKTDLINAGARWQDAEVVVDGQLITS
RKPDDIPAFAAAVAKALAA

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=178, Percent_Identity=29.2134831460674, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI31543380, Length=178, Percent_Identity=29.2134831460674, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI87082219, Length=175, Percent_Identity=42.2857142857143, Blast_Score=133, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571932, Length=178, Percent_Identity=27.5280898876405, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19412; Mature: 19281

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSLTGKTVAVLATDGFEQSELTEPKRLLESWGAKVEVIAPGDSAQIRAWNHTDWGDSV
CCEECCCCEEEEEEECCCCCHHCCCHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCH
AVDRQLEQATAESYDALVLPGGVLNPDTLRTDKQAIAFIRAFSTAQKPVAAICHGPWLLL
HHHHHHHHHHHHCCCEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCEEEE
ESDLVRDREVTSWPSVKTDLINAGARWQDAEVVVDGQLITSRKPDDIPAFAAAVAKALAA
ECHHCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SYSLTGKTVAVLATDGFEQSELTEPKRLLESWGAKVEVIAPGDSAQIRAWNHTDWGDSV
CEECCCCEEEEEEECCCCCHHCCCHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCH
AVDRQLEQATAESYDALVLPGGVLNPDTLRTDKQAIAFIRAFSTAQKPVAAICHGPWLLL
HHHHHHHHHHHHCCCEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCEEEE
ESDLVRDREVTSWPSVKTDLINAGARWQDAEVVVDGQLITSRKPDDIPAFAAAVAKALAA
ECHHCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377; 10568751 [H]