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The map label for this gene is cls [H]

Identifier: 21243598

GI number: 21243598

Start: 3369092

End: 3370654

Strand: Reverse

Name: cls [H]

Synonym: XAC2871

Alternate gene names: 21243598

Gene position: 3370654-3369092 (Counterclockwise)

Preceding gene: 21243599

Following gene: 21243590

Centisome position: 65.13

GC content: 64.68

Gene sequence:

>1563_bases
GTGACAAAGCGGAAATTTTTCAAATGGTTCGGCATTGCGCTGCTGGTGCTGGTGCTGGCCAGCGCGTTATCGCTGTACGG
CTACGGGCGCTTTGCCGACCGCCAACGCGGGCCGGTCAGTCATGTGCTGCCTGCCACGGCGGTCGCGACGCCCATCGACA
AGGTGGTGGCGCCATTGCAACAGGCGCATGCCGATCAGACCGGCATGGTGATCCTGCCGGACAACGTCGATGCATTTGCG
GTACGTGCGCTCACCGCGCGTGCGGCCGGGCGCAGCCTGGATCTGCAGTACTACATCTGGCACGCCGATTTCACCGGCAA
CCTGCTGCACAACGAGTTGCTGCGCGCGGCCGATCGCGGCGTACGCGTGCGATTGCTGCTGGACGACATGAATATCCATG
GCAGCGATTCGGTGCTGGCCGCCCTGGATAGCCATCCGCTGATCGAGATTCGCCTGTTCAACCCGACCCGCGCGCGCGAA
GGCACCTTGATGCGCGGCGTGGAGATGGTGCTGCGCATGTTCAGCATCAACCGCCGCATGCACAACAAGGCCTGGATTGC
CGATGGCCGCATCGCGGTGGTGGGTGGGCGCAACGTGGGCGACGAATATTTCGATGCGGCGCGCGACACCAATTTCATGG
ATATGGATGCGGCGCTGATGGGGCCGGCGGTGGGCCAGGCCGAGCAGGTATTCGATGCGTACTGGAATAGCCCCAATGCC
TTGCCGCTGTCTGCGCTGGTCACCGCAAAACCGCAGGCACTGGAGGCCTTGCGTGGCAGCCTGGACGCCGGCATGGCATC
GGTGCGCGCGCATCCGTATGTGGAGCGGCTCAAGCGCTCCCCAAGCGTGCGCGAACTGATGCAGGGCGACCGCCCGGTGC
ACTGGGTGTCGCAGGCGCGCATCGTTTCCGACCCGCCGGAAAAAGCCGAAGGTGCGCCGCCGCAAGCCGATTGGATGACG
CCAGTGCTGATCGGCGAAATGGCGCACGCACAGCGCGAACTGAAAGTGATTTCGCCGTATTTCGTGCCGGGCGACGAGGG
CATGCGCTGGATCGGCCATCTGCGCCAGCGCAACGTGCGCGTGAGCATTCTGACCAATTCGCTGGCAGCCAACGACGTGG
TGGCAGTGCACAGCGGCTACGCCGGCTATCGCGTGCCGCTTCTGCAGCTGGGCGTGCGCCTGCATGAGCTCAAGCCGATG
GGCAAGCCGGACGGCAGCCTGTTCGGTTCCAGCGGTGCCAGCTTGCATACCAAGGCGTTTGTCGTGGACGACAGCAGCGG
TTTCATCGGCTCGTTCAACCTGGACCCGCGTTCGATGAACCTCAATACCGAAATGGGCCTGTTGTTCAACGACCGTGTGG
TCACCGCGGAGCTGGAGCGGCTGTACAACCACAAGGTCAGTGCGCCAGTGAGTTACCGCGTCACCCTGGACCGGGGCGAA
CTGCGTTGGCACGACGATGCCGCGCAGCCGCCCGAGGTGTGGTCGCGCGAGCCGGCCGCGAGCGTGTGGCGACGTGGTGC
AGCAGCGGTGATGGGCTGGTTGCCGCTGGAGTCGCAGCTGTAG

Upstream 100 bases:

>100_bases
GGTGCTTGTGGGAATTGTCGAGGTTGCTTGTGGCGGCGTCTGCACACCGGTCTGCCCGCGTGGGCTCTACACTGCCGCGC
TGCGCATCGCGGAATCGGCA

Downstream 100 bases:

>100_bases
GTCTGCTCAGGGTGTTGCCCTCATCCGCCCTTCGGGCACCTTCTCCCGCGGGCGGGAGAAGGGAATGTGGCGGTCTTTCA
TGGACGGGAGAAATGCGCGT

Product: cardiolipin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTKRKFFKWFGIALLVLVLASALSLYGYGRFADRQRGPVSHVLPATAVATPIDKVVAPLQQAHADQTGMVILPDNVDAFA
VRALTARAAGRSLDLQYYIWHADFTGNLLHNELLRAADRGVRVRLLLDDMNIHGSDSVLAALDSHPLIEIRLFNPTRARE
GTLMRGVEMVLRMFSINRRMHNKAWIADGRIAVVGGRNVGDEYFDAARDTNFMDMDAALMGPAVGQAEQVFDAYWNSPNA
LPLSALVTAKPQALEALRGSLDAGMASVRAHPYVERLKRSPSVRELMQGDRPVHWVSQARIVSDPPEKAEGAPPQADWMT
PVLIGEMAHAQRELKVISPYFVPGDEGMRWIGHLRQRNVRVSILTNSLAANDVVAVHSGYAGYRVPLLQLGVRLHELKPM
GKPDGSLFGSSGASLHTKAFVVDDSSGFIGSFNLDPRSMNLNTEMGLLFNDRVVTAELERLYNHKVSAPVSYRVTLDRGE
LRWHDDAAQPPEVWSREPAASVWRRGAAAVMGWLPLESQL

Sequences:

>Translated_520_residues
MTKRKFFKWFGIALLVLVLASALSLYGYGRFADRQRGPVSHVLPATAVATPIDKVVAPLQQAHADQTGMVILPDNVDAFA
VRALTARAAGRSLDLQYYIWHADFTGNLLHNELLRAADRGVRVRLLLDDMNIHGSDSVLAALDSHPLIEIRLFNPTRARE
GTLMRGVEMVLRMFSINRRMHNKAWIADGRIAVVGGRNVGDEYFDAARDTNFMDMDAALMGPAVGQAEQVFDAYWNSPNA
LPLSALVTAKPQALEALRGSLDAGMASVRAHPYVERLKRSPSVRELMQGDRPVHWVSQARIVSDPPEKAEGAPPQADWMT
PVLIGEMAHAQRELKVISPYFVPGDEGMRWIGHLRQRNVRVSILTNSLAANDVVAVHSGYAGYRVPLLQLGVRLHELKPM
GKPDGSLFGSSGASLHTKAFVVDDSSGFIGSFNLDPRSMNLNTEMGLLFNDRVVTAELERLYNHKVSAPVSYRVTLDRGE
LRWHDDAAQPPEVWSREPAASVWRRGAAAVMGWLPLESQL
>Mature_519_residues
TKRKFFKWFGIALLVLVLASALSLYGYGRFADRQRGPVSHVLPATAVATPIDKVVAPLQQAHADQTGMVILPDNVDAFAV
RALTARAAGRSLDLQYYIWHADFTGNLLHNELLRAADRGVRVRLLLDDMNIHGSDSVLAALDSHPLIEIRLFNPTRAREG
TLMRGVEMVLRMFSINRRMHNKAWIADGRIAVVGGRNVGDEYFDAARDTNFMDMDAALMGPAVGQAEQVFDAYWNSPNAL
PLSALVTAKPQALEALRGSLDAGMASVRAHPYVERLKRSPSVRELMQGDRPVHWVSQARIVSDPPEKAEGAPPQADWMTP
VLIGEMAHAQRELKVISPYFVPGDEGMRWIGHLRQRNVRVSILTNSLAANDVVAVHSGYAGYRVPLLQLGVRLHELKPMG
KPDGSLFGSSGASLHTKAFVVDDSSGFIGSFNLDPRSMNLNTEMGLLFNDRVVTAELERLYNHKVSAPVSYRVTLDRGEL
RWHDDAAQPPEVWSREPAASVWRRGAAAVMGWLPLESQL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87081826, Length=469, Percent_Identity=40.0852878464819, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 57438; Mature: 57306

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRKFFKWFGIALLVLVLASALSLYGYGRFADRQRGPVSHVLPATAVATPIDKVVAPLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHH
QAHADQTGMVILPDNVDAFAVRALTARAAGRSLDLQYYIWHADFTGNLLHNELLRAADRG
HHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCC
VRVRLLLDDMNIHGSDSVLAALDSHPLIEIRLFNPTRAREGTLMRGVEMVLRMFSINRRM
CEEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
HNKAWIADGRIAVVGGRNVGDEYFDAARDTNFMDMDAALMGPAVGQAEQVFDAYWNSPNA
CCCEEEECCEEEEEECCCCCHHHHHHHCCCCCEECCHHHHCCCCCHHHHHHHHHCCCCCC
LPLSALVTAKPQALEALRGSLDAGMASVRAHPYVERLKRSPSVRELMQGDRPVHWVSQAR
CCCHHEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCEEEHHCCE
IVSDPPEKAEGAPPQADWMTPVLIGEMAHAQRELKVISPYFVPGDEGMRWIGHLRQRNVR
ECCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHCCEE
VSILTNSLAANDVVAVHSGYAGYRVPLLQLGVRLHELKPMGKPDGSLFGSSGASLHTKAF
EEEEECCCCCCCEEEEECCCCCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCCCEEEEEE
VVDDSSGFIGSFNLDPRSMNLNTEMGLLFNDRVVTAELERLYNHKVSAPVSYRVTLDRGE
EEECCCCCEEEECCCCCCCCCCCCCCEEECCEEHHHHHHHHHCCCCCCCEEEEEEEECCC
LRWHDDAAQPPEVWSREPAASVWRRGAAAVMGWLPLESQL
EEECCCCCCCCHHHCCCHHHHHHHCCHHHHHEECCCCCCC
>Mature Secondary Structure 
TKRKFFKWFGIALLVLVLASALSLYGYGRFADRQRGPVSHVLPATAVATPIDKVVAPLQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHH
QAHADQTGMVILPDNVDAFAVRALTARAAGRSLDLQYYIWHADFTGNLLHNELLRAADRG
HHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCC
VRVRLLLDDMNIHGSDSVLAALDSHPLIEIRLFNPTRAREGTLMRGVEMVLRMFSINRRM
CEEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
HNKAWIADGRIAVVGGRNVGDEYFDAARDTNFMDMDAALMGPAVGQAEQVFDAYWNSPNA
CCCEEEECCEEEEEECCCCCHHHHHHHCCCCCEECCHHHHCCCCCHHHHHHHHHCCCCCC
LPLSALVTAKPQALEALRGSLDAGMASVRAHPYVERLKRSPSVRELMQGDRPVHWVSQAR
CCCHHEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCEEEHHCCE
IVSDPPEKAEGAPPQADWMTPVLIGEMAHAQRELKVISPYFVPGDEGMRWIGHLRQRNVR
ECCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHCCEE
VSILTNSLAANDVVAVHSGYAGYRVPLLQLGVRLHELKPMGKPDGSLFGSSGASLHTKAF
EEEEECCCCCCCEEEEECCCCCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCCCEEEEEE
VVDDSSGFIGSFNLDPRSMNLNTEMGLLFNDRVVTAELERLYNHKVSAPVSYRVTLDRGE
EEECCCCCEEEECCCCCCCCCCCCCCEEECCEEHHHHHHHHHCCCCCCCEEEEEEEECCC
LRWHDDAAQPPEVWSREPAASVWRRGAAAVMGWLPLESQL
EEECCCCCCCCHHHCCCHHHHHHHCCHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]